Cell Biology

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Study Finds Protein Cleavage Essential for Healthy Cilia and Cell Signaling

Study Finds Protein Cleavage Essential for Healthy Cilia and Cell Signaling

New research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, Joubert syndrome and other ciliopathies is cut in half to perform two separate functions, both of which are fundamental to the healthy development of children.

30 Jun 2025

Reactivating a Genetic Switch Restores Ear Regeneration in Mice

Reactivating a Genetic Switch Restores Ear Regeneration in Mice

By flipping an evolutionarily disabled genetic switch involved in Vitamin A metabolism, researchers have enabled ear tissue regeneration in mice. Unlike some animals such as fish and salamanders, mammals have limited capacity to regenerate damaged tissues or organs fully.

27 Jun 2025

Worm Species Reveal Deep Genetic Similarities Across Evolutionary Time

Worm Species Reveal Deep Genetic Similarities Across Evolutionary Time

Two species of worms, separated by 20 million years of evolution, have been found to activate their genes in nearly identical ways as they develop from a single cell to a fully formed organism.

27 Jun 2025

Tracing the Genetic Mosaic of India Through Ancient Ancestry and Modern Genomes

Tracing the Genetic Mosaic of India Through Ancient Ancestry and Modern Genomes

India's population is genetically one of the most diverse in the world, yet it remains underrepresented in global datasets.

27 Jun 2025

LMU Study Reveals How Life Could Begin Without Cell Membranes

LMU Study Reveals How Life Could Begin Without Cell Membranes

LMU researchers have demonstrated a possible mechanism for metabolic processes without cell membranes in water-filled pores.

27 Jun 2025

Scientists Grow Liver Organoids with Functional Blood Vessels

Scientists Grow Liver Organoids with Functional Blood Vessels

Scientists from Cincinnati Children's and colleagues based in Japan report achieving a major step forward in organoid technology--producing liver tissue that grows its own internal blood vessels.

26 Jun 2025

Nucleus Identified as the Pacemaker of Cell Division

Nucleus Identified as the Pacemaker of Cell Division

Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought.

26 Jun 2025

Genetically Similar Bacteria Show Unexpected Diversity in Shape and Behavior

Genetically Similar Bacteria Show Unexpected Diversity in Shape and Behavior

Genetically similar bacteria can differ in shape and behavior, even in lab settings. A recent study shows that this variability impacts microbial fitness, virulence, and our understanding of gut microbiota.

26 Jun 2025

Fruit Fly Study Uncovers Key Mechanisms Behind Collective Cell Migration

Fruit Fly Study Uncovers Key Mechanisms Behind Collective Cell Migration

Researchers uncover how Plexin A and Semaphorin 1b regulate collective cell migration in fruit fly testes, offering insights into organ development, cancer metastasis, and tissue engineering.

26 Jun 2025

Fluorescent Molecules Offer Unprecedented Insight into Cell Structures

Fluorescent Molecules Offer Unprecedented Insight into Cell Structures

Scientists have long used fluorescent dyes—which emit light—to research cell structures and activities.

25 Jun 2025

Newly Evolved Genes Found to Influence Human Cell Division

Newly Evolved Genes Found to Influence Human Cell Division

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria.

24 Jun 2025

Mapping Life’s Origins with Billions of DNA Barcodes

Mapping Life’s Origins with Billions of DNA Barcodes

A landmark study by WEHI scientists has shed new light on one of the most fundamental mysteries of biology: how cells divide and grow into the complex structures that make up our bodies.

24 Jun 2025

Combating Tumor Resistance and Exhaustion in Lymphoma

Combating Tumor Resistance and Exhaustion in Lymphoma

The study reviews CAR-T cell advancements in lymphoma treatment, addressing T cell exhaustion and tumor immune evasion with next-generation CAR modifications.

24 Jun 2025

Anthrobots Reveal How Cells Can Build New Shapes Without Genetic Edits

Anthrobots Reveal How Cells Can Build New Shapes Without Genetic Edits

Modern humans have existed for over 200,000 years, and each new generation has begun with a single cell-dividing, changing shape and function, organizing into tissues, organs, and limbs.

23 Jun 2025

New Technique Enhances Three Dimensional Immunolabeling in Thick Tissues

New Technique Enhances Three Dimensional Immunolabeling in Thick Tissues

Three dimensional immunohistochemistry (3D-IHC) has transformed our ability to visualize the spatial arrangement of cells and molecules in intact tissues.

20 Jun 2025

In Vivo CAR T Cell Generation Shows Promise for Cancer and Autoimmune Diseases

In Vivo CAR T Cell Generation Shows Promise for Cancer and Autoimmune Diseases

Researchers present a new method to safely and preferentially generate CAR T cells directly inside the body using targeted lipid nanoparticles that deliver mRNA directly to T cells.

20 Jun 2025

Do Genetic Variants That Affect DNA Methylation Influence Colorectal Cancer Risk or Outcomes?

Do Genetic Variants That Affect DNA Methylation Influence Colorectal Cancer Risk or Outcomes?

The study identifies genetic variants influencing colorectal cancer risk through DNA methylation, suggesting new avenues for targeted screening and prevention.

20 Jun 2025

New Study Reveals Varied CAR T-Cell Therapy Benefits in Large B-Cell Lymphoma

New Study Reveals Varied CAR T-Cell Therapy Benefits in Large B-Cell Lymphoma

A study identifies three patient subgroups in large B-cell lymphoma, revealing distinct responses to CD19 CAR T cell therapy and enhancing precision medicine.

20 Jun 2025

Organotypic Model of the Human Gut Epithelium Demonstrates Genetic Determinants of Shigella Colonization

Organotypic Model of the Human Gut Epithelium Demonstrates Genetic Determinants of Shigella Colonization

A study in Nature Genetics uses organotypic gut models to reveal genome-wide genetic determinants of Shigella colonization, spotlighting type III secretion system effectors as crucial for early infection.

20 Jun 2025

UQ Tech Bringing Regenerative Medicines Closer Than Ever

UQ Tech Bringing Regenerative Medicines Closer Than Ever

Tiny gel droplets enhanced with University of Queensland technology could open new pathways to repairing and replacing damaged organs.

20 Jun 2025

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