Cell Biology

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Human Kidney Organoids Offer New Insights into APOL1-Mediated Kidney Disease

Chronic kidney disease (CKD) impacts over 700 million individuals globally and arises from a combination of genetic and environmental influences, along with pre-existing health conditions.

3 Oct 2025

New Insights Into How Pathogens Build Protein Machinery for Survival in the Gut

A new study, led by researchers at the University of Liverpool, has revealed how pathogenic bacteria construct tiny protein-based compartments, known as Eut microcompartments, which enable them to digest ethanolamine - a nutrient commonly found in the gut.

3 Oct 2025

Scientists Derive Authentic Embryonic Stem Cells From Chickens and Other Birds

Egg whites may be perfect for a health-conscious breakfast, but egg yolks turned out to be the key ingredient for cultivating bird embryonic stem cells (ESCs) in the lab.

30 Sep 2025

Actin Scaffold Protects Cancer Cell Nuclei Under Mechanical Stress

Researchers from the Cluster of Excellence CIBSS have demonstrated that an actin scaffold stabilizes the cell nucleus upon mechanical stress.

30 Sep 2025

Scientists Discover Genetic Switch that Controls Candida's Toxin Production

The yeast fungus Candida albicans employs the toxin candidalysin not only to cause infections but also to inconspicuously colonize the oral mucosa—though only in precisely regulated amounts.

29 Sep 2025

Chromosome Zippers Rely on DNA Junctions to Safeguard Fertility

Every new life begins after a genetic shuffle. When organisms make eggs or sperm, maternal and paternal chromosomes pair up and swap pieces of DNA in a process called crossing over.

26 Sep 2025

RyR1-Mediated CICR Plays Minimal Role in Normal Skeletal Muscle Contraction

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release.

26 Sep 2025

Study Reveals How Lymphatic Cells Preserve Immune Memory

A study published today in Nature Communications describes how lymphatic endothelial cells assist in generating robust immune memory, offering new insights into how the immune system functions.

26 Sep 2025

Protein Networks Expose New Therapeutic Targets for Alzheimer's

A recent study conducted by the Icahn School of Medicine at Mount Sinai provides one of the most thorough insights to date regarding the interactions of brain cells in Alzheimer’s disease, illustrating protein networks that expose communication breakdowns and highlight potential new therapeutic avenues for treatment.

26 Sep 2025

Discovery Reveals Spinal Neurons as Active Players in Sexual Behavior

For decades, it was thought that while the brain orchestrated male sexual behavior – arousal, courtship, and copulation – the spinal cord merely executed the final act: ejaculation. But a study from the Champalimaud Foundation (CF) challenges that tidy division.

25 Sep 2025

Astrocytes Found to Integrate Signals from Multiple Neurons

A collaborative French-Swiss study reveals a previously unknown role for astrocytes in the brain's information processing.

25 Sep 2025

Study Identifies a Cellular Mechanism That Alters the Gut Microbiome

It is well established that gut microbiome composition plays a pivotal role in human health – yet the precise connections are still not fully elucidated.

24 Sep 2025

Breakthrough in Treating Age-Related Macular Degeneration with Retinal Stem Cells

In the United States, age-related macular degeneration is a leading cause of irreversible vision loss in people who are 60 and older.

24 Sep 2025

Aurora A Enzyme Guides Proper Nuclear Formation in Dividing Cells

Every time a eukaryotic cell divides, it faces a monumental challenge: It must carefully duplicate and divide its genetic material (chromosomes) equally, and then rebuild the nuclear envelope around the separated halves.

24 Sep 2025

New Research Challenges the Static View of Chromosome Shape

An international team of researchers from the Francis Crick Institute, Imperial College London, Waseda University, and the Cancer Institute of the Japanese Foundation for Cancer Research has reshaped the concept of chromosome shape, discovering that they are not always stable X-shaped structures but are constantly in flux as cell division occurs.

24 Sep 2025

Lipids Play a Regulatory Role in LC3-Associated Phagocytosis

LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles.

23 Sep 2025

Metabolic Signals Shape the Rhythm of Embryonic Segmentation

Pregnant women rely on a balanced diet and supplements to deliver proper nutrients to their babies, to ensure they grow healthfully.

22 Sep 2025

Alpha Cells may Produce More Bioactive GLP-1 Than Previously Believed

A new study from Duke University School of Medicine is challenging long-standing views on blood sugar regulation - and pointing to a surprising new ally in the fight against type 2 diabetes.

22 Sep 2025

Novel Chromosome Identification System Overcomes Longstanding Bottleneck in Alfalfa Cytogenetics

Karyotype analysis is fundamental to understanding genetic makeup, diversity, and adaptation in plants. Yet, distinguishing individual chromosomes remains challenging in species with small, uniform chromosomes and complex polyploid genomes such as alfalfa.

22 Sep 2025

Study Uncovers How Cell Clustering Affects Glioblastoma Aggressiveness

A new study, led by researchers at Sylvester Comprehensive Cancer Center part of the University of Miami Miller School of Medicine, captured details of glioblastoma that had never before been seen and revealed a surprise finding: Glioblastoma cells that "cluster" together with other cells of the same type are less deadly than those that disperse from these clusters.

22 Sep 2025