Disease/Infection News

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New host protease determinants facilitating the infection of SARS-CoV-2 identified

Researchers from Department of Microbiology, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified novel host protease determinants, that facilitate the infection of SARS-CoV-2, including the Omicron variant, which provided new targets for combating the pandemic.

22 Feb 2023

Accelerating the structure-guided discovery of chemogenetic tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells. One way is by using a tool called DREADDs, which stands for Designer Receptors Activated by Designer Drugs.

21 Feb 2023

Role of probiotics and functional materials in the treatment of intestinal inflammation

Maintenance of sulfomucin is a key end point in the treatment of diarrhea and inflammatory bowel disease (IBD). However, the mechanism underlying the microbial sense to sulfomucin are poorly understood, and to date, there are no therapies targeting the secretion and maturation of sulfomucin in IBD. Considering the important role of gut microbiota in host immune regulation, maintain sulfomucin by modulating the gut microbiota is inspired.

20 Feb 2023

Novel molecule prevents cells from infection with SARS-COV-2

The virus that causes COVID-19, called SARS-CoV-2, uses its spike protein in order to stick to and infect our cells. The final step for the virus to enter our cells is for part of its spike protein to act like a twist tie, forcing the host cell's outer membrane to fuse with the virus.

20 Feb 2023

Expert releases open-source compilation of the SARS-CoV-2 molecular structure

A biomedical researcher at the Lankenau Institute for Medical Research (LIMR), part of Main Line Health, has created a groundbreaking resource for scientists seeking to develop new and better vaccines in the fight against COVID-19.

19 Feb 2023

Study identifies cell type crucial for successful immunotherapies for chronic viral infections

An international study led by researchers from the Infection Biology Laboratory at the UPF Department of Medicine and Life Sciences (MELIS) establishes that one type of dendritic cells is crucial for the success of immunotherapeutic treatments to control chronic viral infections.

17 Feb 2023

Researchers reveal link immune system genetics and a person's ability to resist new COVID-19 variants

An international team including researchers from the HSE University Faculty of Biology and Biotechnology has found a link between certain genetic features of the immune system and one's ability to effectively resist new waves of COVID-19.

17 Feb 2023

AutoPLP helps detect mutating pathogenic variants quickly and accurately

As we now know from our experience with the COVID-19 pandemic, the microbes responsible for some infections can rapidly mutate into variants that evade detection and treatment.

16 Feb 2023

Extracts from two common wild plants block SARS-CoV-2 from entering human cells

Two common wild plants contain extracts that inhibit the ability of the virus that causes COVID-19 to infect living cells, an Emory University study finds.

13 Feb 2023

Measurement of plasma D-dimer levels can be useful when diagnosing periprosthetic joint infection

Measurement of plasma D-dimer levels – a test more commonly used to detect blood-clotting disorders – can provide useful information when making the difficult diagnosis of periprosthetic joint infection (PJI), reports a study in The Journal of Bone & Joint Surgery.

13 Feb 2023

A protein in the lung forms a natural protective barrier against SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

10 Feb 2023

Novel compound curtails influenza virus replication

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to exploit this for the treatment of influenza.

10 Feb 2023

Psychological trauma related to HIV could make it difficult to end the AIDS epidemic

Failing to address the psychological trauma experienced by many older people living with HIV/AIDS will make it difficult, if not impossible, to end the epidemic, according to a Rutgers study.

8 Feb 2023

Microbiome therapeutic linked to quality of life improvement in patients with recurrent C. diff infection

Kevin Garey, professor of pharmacy practice and translational research at the University of Houston College of Pharmacy is reporting the first well-controlled study to demonstrate that a microbiome therapeutic, SER-109, is associated with significant quality of life improvement in patients with the debilitating recurrent infection and disease caused by Clostridium difficile (or C. diff).

1 Feb 2023

Disease/Infection News

New host protease determinants facilitating the infection of SARS-CoV-2 identified

Accelerating the structure-guided discovery of chemogenetic tools

Role of probiotics and functional materials in the treatment of intestinal inflammation

Novel molecule prevents cells from infection with SARS-COV-2

Expert releases open-source compilation of the SARS-CoV-2 molecular structure

Study identifies cell type crucial for successful immunotherapies for chronic viral infections

Researchers reveal link immune system genetics and a person's ability to resist new COVID-19 variants

AutoPLP helps detect mutating pathogenic variants quickly and accurately

Extracts from two common wild plants block SARS-CoV-2 from entering human cells

Measurement of plasma D-dimer levels can be useful when diagnosing periprosthetic joint infection

A protein in the lung forms a natural protective barrier against SARS-CoV-2 infection

Novel compound curtails influenza virus replication

Psychological trauma related to HIV could make it difficult to end the AIDS epidemic

Microbiome therapeutic linked to quality of life improvement in patients with recurrent C. diff infection

UNC research describes another layer to the challenge of HIV latency

Genomic study helps retrace origin and spread of Shigellosis outbreak in Seattle

Research supports the safety and efficacy of COVID-19 vaccination in cancer patients receiving immunotherapy

The Native Antigen Company expands infectious disease portfolio to include Sudan Ebolavirus Boniface 1976 Glycoprotein

New framework for developing ecological countermeasures to prevent pandemics

Unraveling sex determination in Bursaphelenchus nematodes: A path towards pest-control

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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