Fluorescence

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High-speed cell sorter rapidly isolates and quantifies cells with complex cellular phenotypes

Isolating individual cells with complex phenotypes – which is key to understanding how these cells function, including to inform disease – is a technological challenge. Now, overcoming this hurdle, researchers present a high-speed cell sorter that uses fluorescence imaging to enable genome-scale studies of complex phenotypes.

21 Jan 2022

Label-free device enables in-situ tracking of cell development and maturation

The biological intracellular microenvironment is diverse, consisting of several cell compartments and intracellular components.

20 Jan 2022

Researchers discover a key mechanism used by Zika virus to evade cell’s antiviral response

The world knows SARS-CoV-2 intimately now, but there are more than 200 virus species capable of infecting humans and causing disease.

19 Jan 2022

Scientists develop molecules for myocardial PET and fluorescence bimodal imaging

Heart disease continues to be a leading cause of mortality and morbidity across the globe. Positron emission tomography (PET) has slowly become a remarkable technology of a non-invasive technique for accurately diagnosing cardiac diseases.

11 Jan 2022

Scientists use fruit fly embryos to study immune cell invasion

To fight infections and heal injuries, immune cells need to enter tissue. They also need to invade tumors to fight them from within.

7 Jan 2022

Live-cell probes enable visualization of the elongation phase of transcription

A genetically encoded “live-cell” probe developed by scientists from Tokyo Tech pinpointed phosphorylated Ser2 in the enzyme RNA polymerase II.

7 Dec 2021

New two-photon microscope provides unprecedented brain-imaging ability

Advancing our understanding of the human brain will require new insights into how neural circuitry works in mammals, including laboratory mice.

3 Dec 2021

New 3D map provides precise locations of blood vessels and stem cells in a a mouse skull

Johns Hopkins Medicine scientists have used glowing chemicals and other techniques to create a 3D map of the blood vessels and self-renewing "stem" cells that line and penetrate a mouse skull.

19 Nov 2021

Researchers devise simple and rapid method for detecting bovine amyloid

Amyloidosis, a multifaceted disease group results due to the misfolded “amyloid” protein deposits in different tissues.

8 Oct 2021

Rapid, more accurate test to detect antibodies against SARS-CoV-2 spike protein

Japanese researchers have come up with a highly accurate, rapid test for identifying antibodies against the SARS-CoV-2 spike protein in human serum.

19 Jul 2021

Developing a portable tool to detect street drug ‘spice’

AZoLifeSciences speaks to researchers from the University of Bath about their latest research that led to the development of a device that can detect 'spice'.

From University of Bath 28 Apr 2021

New fluorescent polymer binds to blood in fingerprint to create high-contrast images

Criminals who are very cautious often clean a crime scene by wiping away visible blood and fingerprints.

23 Apr 2021

New fluorescent probe that can discriminate B lymphocytes over T lymphocytes

Human blood contains several different components, including plasma, red blood cells (RBCs), white blood cells (WBCs), and platelets.

15 Apr 2021

Microfluidic probe sends free radicals on live cells

Is there a way to chemically manipulate small, confined areas on cellular surfaces? Scientists have developed a microfluidic probe to send a flow of free radicals on live cells and track the outcome using fluorescence imaging.

7 Apr 2021

Unique mini-microscope enables imaging of brain activity in freely moving mice

Researchers from the University of Minnesota Twin Cities College of Science and Engineering and Medical School have developed a unique head-mounted mini-microscope device that allows them to image complex brain functions of freely moving mice in real time over a period of more than 300 days.

6 Apr 2021

New technique based on AI can automate and streamline seed quality analysis

In Brazil, researchers affiliated with the Center for Nuclear Energy in Agriculture (CENA) and the Luiz de Queiroz College of Agriculture (ESALQ), both part of the University of São Paulo (USP), have developed a methodology based on artificial intelligence to automate and streamline seed quality analysis, a process required by law and currently done manually by analysts accredited with the Ministry of Agriculture.

22 Mar 2021

Novel microscopy system for scanless 3D measurement with submicron resolution

The National Institute of Information and Communications Technology (NICT), Tohoku University, Toin University of Yokohama, and Japan Science and Technology Agency (JST) have succeeded in developing a scanless high-speed holographic fluorescence microscopy system with submicron resolution for a 3D space.

1 Feb 2021

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.

27 Jan 2021

Altered sugar composition impacts cell-to-surface adhesion

Biotechnologists measure the forces with which algae cells adhere to surfaces and move on them. How can cells adhere to surfaces and move on them? This is a question that was investigated by an international team of researchers headed by Prof. Michael Hippler from the University of Münster and Prof. Kaiyao Huang from the Institute of Hydrobiology (Chinese Academy of Sciences, Wuhan, China).

4 Jan 2021

A protein encourages cell stickiness during development

Tohoku University scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development.

28 Dec 2020