Fluorescence

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ORNL Scientists Develop Fluorescent Biosensor to Track RNA in Plants

Scientists at Oak Ridge National Laboratory have developed a first-ever method of detecting ribonucleic acid, or RNA, inside plant cells using a technique that results in a visible fluorescent signal.

16 Apr 2025

New Chromosome Identification System Revolutionizes Alfalfa Research

In a recent study, scientists have developed a revolutionary chromosome identification system for alfalfa, one of the world's most economically vital forage crops.

19 Mar 2025

Novel Tool Uses DNA Barcode System for Deep-Tissue RNA and Protein Imaging

For the Liu Lab, necessity is truly the mother of invention. The researchers were examining how the 3D organization of the genome controls development and needed to image hundreds of RNA molecules in a thick tissue sample to understand where and how genes were being expressed in cells.

13 Mar 2025

Breakthrough Fluorescent Dye Sets New Standard for Long-Term Cellular Imaging

A research team at POSTECH (Pohang University of Science and Technology) has successfully developed a super-photostable organic dye after two years of dedicated research-demonstrating perseverance akin to that of Marie Curie, who painstakingly extracted just 0.1 grams of radium from eight tons of ore to earn her Nobel Prize.

28 Feb 2025

New Method Enables 20 Color Bioluminescent Imaging for Live Cells

Imaging live cells with fluorescent proteins has long been a crucial technique for understanding cellular behavior. While bioluminescent proteins offer several advantages over fluorescent proteins, the limited availability of color variants has made it difficult to observe multiple targets simultaneously.

23 Jan 2025

New Method Improves Quantification of Endocytosis in Living Cells

Living cells and tissues show a high capacity to absorb various chemical compounds from the surrounding environment.

23 Dec 2024

Scientists Use Cell Density to Control Tissue Formation

Genes aren't the sole driver instructing cells to build multicellular structures, tissues, and organs.

20 Nov 2024

New Bioluminescent Proteins Enable Excitation-Free Imaging in Living Organisms

Bioluminescence is the natural chemical process of light creation in some living creatures that makes fireflies flicker and some jellyfish glow.

14 Nov 2024

Discover Photon etc.'s latest innovation: LightIR

Photon etc. announces the launch of its newest instrument, the LightIR system, designed for preclinical fluorescence imaging and clinical research.

From Photon etc. 31 Oct 2024

Research Sheds Light on Biofilm Bacteria Interactions and Competition

Biofilms -; slimy communities of bacteria -; grow on all sorts of surfaces: from glaciers and hot springs to plant roots, your bathtub and fridge, wounds, and medical devices such as catheters.

18 Oct 2024

Researchers Develop Fluorescent Biosensor to Study PKC Activity

Working in organoid models, researchers at University of California San Diego School of Medicine have developed a new tool to study protein-kinase C (PKC) enzymes, which play a critical role in cell growth, differentiation and survival.

14 Oct 2024

Uncovering Hidden Bacteria in Antibiotic Resistance

Imagine a country with a billion people, where every individual has different interests and different goals. You will never know their interests and goals until you ask them, but asking a billion people is not an easy task.

7 Oct 2024

A Novel Biosensor for Calcium Detection in Fruit Flies, Zebrafish, and Mice

In 2021, the Janelia group leaders reported that they had developed a way to combine Schreiter's engineered protein biosensors and Lavis's bright, fluorescent Janelia Fluor dyes.

23 Sep 2024

New Insights into How Mutant p53 Promotes Tumor Growth

Research from the Federal University of Rio de Janeiro (UFRJ) and the National Institute of Science and Technology for Structural Biology and Bioimaging (INBEB) in Brazil has uncovered a critical mechanism by which mutations in the p53 protein-;a key tumor suppressor known as the "guardian of the genome"-;turn other proteins into cancer-promoting agents

17 Sep 2024

Developing Techniques for Imaging Biomolecules

Scientists are working to create quicker, more quantitative, and more publicly available methods of seeing biomolecules in living cells to speed up biotechnology discoveries, such as the production of lifesaving drugs.

11 Sep 2024

New Imaging Technique Offers Clearer View of Brain Function

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue than traditional two-photon microscopy, the new approach could provide a clearer view of how neurons communicate in real time, leading to new insights into brain function and neurological diseases.

16 Aug 2024