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Novel Approach Provides a Flexible Foundation for Measuring Coronavirus Protease Activity

A research team has computationally designed a synthetic peptide that enables modular detection of the enzymatic activity of coronavirus 3C-like protease (3CLPro), an enzyme essential for viral replication and maturation.

13 Aug 2026

Scientists Map Overlapping Fluorescent Proteins Using Advanced Lifetime Microscopy Techniques

Fluorescent protein imaging is an indispensable tool in life science research, enabling visualization of protein movement and localization, gene expression, signaling pathways, protein-protein interactions, and more.

12 Aug 2026

New Imaging Workflow Tracks Nanoplastics Distribution in Neonatal Mouse Brains

Nanoplastics-plastic particles smaller than one micrometer-are generated through the degradation and abrasion of plastic products and are increasingly detected in food, drinking water, air, and biological tissues.

30 Jul 2026

Scientists Discover How Heart Muscle Cells Remodel Actin Filaments

Biophysicists unraveled a mystery of how muscles form at the molecular level and how they maintain their function.

30 Jul 2026

Scientists Use Advanced 3D Imaging to Visualize Joint Nerves

Temporomandibular disorders (TMDs) are a group of more than 30 conditions that cause pain and dysfunction in the jaw.

8 Jul 2026

Extracellular Acidosis Disrupts Internal Transport Systems of Living Cells

A new scientific study led by the Universidad Carlos III de Madrid (UC3M) describes the mechano-chemical mechanism by which the acidity of the cellular environment destabilizes microtubules, the "avenues" that organize internal cellular traffic.

27 May 2026

New VIS-Fbs Technology Offers Sharper Images of Living Cellular Processes

Fluorescent proteins have revolutionized science, enabling researchers to tag and visualize individual molecules in living cells, tissues, and animals.

23 Apr 2026

New Molecular Imaging Technology Illuminates Proteins Inside Living Cells

Fluorescent probes have transformed modern biology by allowing researchers to tag and visualize individual molecules in living cells, tissues, and animals.

22 Apr 2026

New Technology Uses Genetic Passcodes to Protect High-Value Engineered Cell Lines

In recent years, the Centers for Disease Control and Prevention, the Department of Homeland Security, and other authorities have flagged a record number of unauthorized shipments of biological materials.

11 Apr 2026

New Multicolor Electron Microscopy Reveals Cell Structure and Proteins in Vivid Detail

Scientists have developed a new imaging technique that uses a novel contrast mechanism in bioimaging to merge the strengths of two powerful microscopy methods, allowing researchers to see both the intricate architecture of cells and the specific locations of proteins-all in vivid color and at nanometer resolution.

23 Feb 2026

Artificial Intelligence Enables Stable Intrabody Design in Cells

A new artificial intelligence-driven pipeline developed in a collaborative research combines protein structure prediction, sequence design, and live-cell screening together to enable rapid conversion of antibody sequences into functional intracellular antibodies (intrabodies) that are stable within living cells.

16 Feb 2026

Selective Mitophagy Enables Invasive Growth of Anthracnose Pathogen

Anthracnose is one of the most damaging fungal diseases affecting woody oil crops and many other plants, causing severe yield losses worldwide.

4 Feb 2026

Integrated Micro-Optical System Revolutionizes Tissue Monitoring

Microphysiological systems and organ-on-chip technologies are increasingly used to model human tissues outside the body, offering alternatives to animal experiments and traditional cell cultures.

2 Feb 2026

Engineered Human Skin Acts as a Living Biosensor for Inflammation

Implanted living skin-based biosensors offer a breakthrough in inflammation tracking, providing real-time biomarker monitoring without invasive procedures.

21 Jan 2026

Passive Adaptation Balances Protein Synthesis and Degradation in Cells

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids but cannot simply accumulate inside the cell forever.

23 Dec 2025

MiniVolt Microscope Captures Neuron Voltage Signals in Freely Moving Animals

Researchers have built a tiny, lightweight microscope that captures neuron activity with unprecedented speed that can be used in freely moving animals.

8 Dec 2025

UBQLN2 Liquid Droplets Found to Catalyze Early α-Synuclein Aggregation

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons and leading to the motor symptoms of the disease. α-synuclein (α-syn), a misfolded protein, aggregates and forms fibrils, which leads to the formation of LBs.

27 Nov 2025