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Cancer Stem Cells Induce Macrophage Senescence, Creating Conditions for Tumor Formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

15 Nov 2023

Rare Genetic Variant Found to Protect Against Alzheimer's Disease

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

14 Nov 2023

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.

14 Nov 2023

Stanford Researchers Discover New Mechanism for Breast Cancer Invasion

The majority of breast cancers start in the lining of a breast milk duct and, if they remain there, are very treatable.

14 Nov 2023

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

14 Nov 2023

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

10 Nov 2023

SPT5 Identified as a Potential Target Protein for Treatment of MYC-Dependent Cancers

MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins - with clear consequences for the tumor.

8 Nov 2023

Epigenetic Changes Drive Cancer Development

Every cell makes its own proteins by accessing the genetic information on its genes. Changes in this information, called mutations, may ruin the function of the affected proteins.

7 Nov 2023

Researchers Enhance CAR-T Cell Therapy by Preventing T-Cell Exhaustion

CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful.

7 Nov 2023

Prime Editing and Base Editing Could Revolutionize Treatment for Phenylketonuria

Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals' genetic ancestry. PKU causes an amino acid-;called phenylalanine (Phe)-;to build up in the bloodstream.

3 Nov 2023

Study Identifies Risk Genes and Regulatory Variants for Colorectal Cancer by Integrating Multi-Omics Data

This study was led by Prof. Xiao-Ping Miao' team from the School of Public Health, Wuhan University, in collaboration with Prof. Shaokai Zhang from the Henan Cancer Hospital.

2 Nov 2023

Obesity Susceptibility may be Written Into Molecular Processes of Human Cells

A susceptibility to gain weight may be written into molecular processes of human cells, a Washington State University study indicates.

2 Nov 2023

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

Enhancing treatment options for triple-negative breast cancer (TNBC), a highly aggressive tumor with a grim prognosis and limited therapeutic possibilities has proven to be a formidable challenge.

31 Oct 2023

New Way to Visualize Tumors During Surgery

Surgeons often face the challenge of achieving precise tumor removal while preserving healthy tissue. Traditionally, they rely on their visual and tactile senses to determine where to make incisions.

17 Oct 2023

Researchers Develop Drug Targeting lncRNA TUG1 to Control Brain Tumor Growth in Mice

A new study has unraveled a crucial link between how cancer cells cope with replication stress and the role of Taurine Upregulated Gene 1 (TUG1). By targeting TUG1 with a drug, the researchers were able to control brain tumor growth in mice, suggesting a potential strategy to combat aggressive brain tumors such as glioblastomas.

13 Oct 2023

Lactate Oxidase Nanocapsules Help the Immune System to Fight and Kill Solid Tumors

UCLA researchers have developed a new treatment method using a tiny nanocapsule to help boost the immune response, making it easier for the immune system to fight and kill solid tumors.

13 Oct 2023

New Microscopy Technique Reveals Unprecedented Details of Amyloid Plaques in Alzheimer's Disease

Researchers from the Universitat Autònoma de Barcelona (UAB), the Karolinska Institute (KI), and the biotechnology company BioArctic, both in Sweden, have combined STED microscopy, a technology that allows super-resolution visualization, and a new antibody recently created to observe the amyloidogenic aggregates characteristic of Alzheimer's disease.

12 Oct 2023

Study Uncovers Novel Genes Linked to Coronary Artery Calcification

An international team of scientists has identified nearly a dozen genes that contribute to calcium buildup in our coronary arteries that can lead to life-threatening coronary artery disease, a condition responsible for up to one in four deaths in the United States.

12 Oct 2023

Researchers Develop Bio-Inspired Drug to Boost Efficacy of Cancer Immunotherapy

A new, bio-inspired drug restores the effectiveness of immune cells in fighting cancer, a team led by researchers at The University of Texas at Austin has found.

10 Oct 2023

Study Links Autism Gene to Broad Spectrum of Molecular and Cellular Defects

Researchers have used CRISPR gene editing, stem cells and human neurons to study the impact of a gene that is commonly mutated in autism.

6 Oct 2023

Medical Condition News

Cancer Stem Cells Induce Macrophage Senescence, Creating Conditions for Tumor Formation

Rare Genetic Variant Found to Protect Against Alzheimer's Disease

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Stanford Researchers Discover New Mechanism for Breast Cancer Invasion

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

SPT5 Identified as a Potential Target Protein for Treatment of MYC-Dependent Cancers

Epigenetic Changes Drive Cancer Development

Researchers Enhance CAR-T Cell Therapy by Preventing T-Cell Exhaustion

Prime Editing and Base Editing Could Revolutionize Treatment for Phenylketonuria

Study Identifies Risk Genes and Regulatory Variants for Colorectal Cancer by Integrating Multi-Omics Data

Obesity Susceptibility may be Written Into Molecular Processes of Human Cells

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

New Way to Visualize Tumors During Surgery

Researchers Develop Drug Targeting lncRNA TUG1 to Control Brain Tumor Growth in Mice

Lactate Oxidase Nanocapsules Help the Immune System to Fight and Kill Solid Tumors

New Microscopy Technique Reveals Unprecedented Details of Amyloid Plaques in Alzheimer's Disease

Study Uncovers Novel Genes Linked to Coronary Artery Calcification

Researchers Develop Bio-Inspired Drug to Boost Efficacy of Cancer Immunotherapy

Study Links Autism Gene to Broad Spectrum of Molecular and Cellular Defects

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