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Fruit Fly Immune Responses May Help Predict Human Susceptibility to New Viruses

Study on Drosophilidae shows positive correlations in viral susceptibility, highlighting evolutionary trends that may predict novel virus threats to humans.

12 Feb 2025

Researchers Uncover Genomic Drivers Behind Aggressive Breast Cancer

Breast cancers can be classified into subgroups that hint at the aggressiveness of the cancer and the likelihood that the patient will experience a recurrence years after their initial diagnosis.

11 Feb 2025

Study Uncovers Immune Cell Interaction Driving Aggressive Brain Tumor Growth

A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, according to new research led by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins University School of Medicine.

11 Feb 2025

Understanding Plant Repair of Light-Damaged Photosystems

More than two billion years ago, cyanobacteria started to produce oxygen in the primarily toxic atmosphere of Earth.

11 Feb 2025

Breakthrough Research Unlocks Key Genetic Insights into Multimorbidity

The largest study to date to analyze millions of both genetic and patient records on the long-term health conditions of later life has identified opportunities for new ways to prevent and treat multiple overlapping conditions.

10 Feb 2025

BioMed X and Merck Partnership Makes Significant Strides in Understanding ecDNA Biology

German independent research institute BioMed X announces the successful completion of its oncology research project in partnership with Merck. The data generated by this project has been acquired by Merck for further development, potentially leading to new therapeutic approaches in precision oncology.

10 Feb 2025

New Research Identifies Brain Cells Linked to Alcohol-Induced Insomnia

Alcohol use disorder, which affects over 10% of Americans, can lead to persistent and serious insomnia.

8 Feb 2025

Researchers Identify Key Mechanism in Transformation of Stem Cells to Cancer Cells

Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise.

5 Feb 2025

Study Shows How Anticancer Drug is Drawn into Cancer Cells

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell.

5 Feb 2025

CRISPR-Engineered Fat Cells Show Promise in Preclinical Cancer Models

Cancer is rarely discussed in the same breath as liposuction or plastic surgery.

5 Feb 2025

Revolutionary Model Identifies Tumor-Fighting Immune Cells in Lung Cancer

Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg~Kimmel Institute for Cancer Immunotherapy have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune checkpoint inhibitors.

4 Feb 2025

Scientists Decode ApoB100 Structure for Targeted Heart Disease Treatments

Low-density lipoproteins (LDL) - commonly known as bad cholesterol - have long been on scientists' radar as a major contributor to heart disease.

4 Feb 2025

Gut Microbes May Explain Link Between Sugar-Sweetened Beverages and Diabetes

It is well known that consuming sugary drinks increases the risk of diabetes, but the mechanism behind this relationship is unclear.

3 Feb 2025

Understanding How α2δ Protein Mutations Influence Brain Development in Autism

A recent study has uncovered how specific genetic mutations in α2δ-1 and α2δ-3 proteins linked to autism spectrum disorders (ASD) alter neuronal functionality. These mutations significantly reduce the proteins’ membrane expression and synaptic targeting but do not impair calcium channel activity or trans-synaptic signalling.

3 Feb 2025

First Cell Atlas of Focal Cortical Dysplasia Offers New Insights for Treatment

Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia (FCD), a malformation of the cerebral cortex that leads to drug-resistant epilepsy.

31 Jan 2025

Research Paves Way for Off-the-Shelf CAR T Cells for Cancer Treatment

CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a patient's own immune T cells and engineering them to recognize specific targets on the surface of the cancer cell.

31 Jan 2025

Researchers Apply Advanced AI Genetics Models to Study Parkinson's Disease

Researchers from the Cleveland Clinic Genome Center have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that can potentially be repurposed for PD treatment.

29 Jan 2025