Proteomics

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Massive study on plasma proteome enhances understanding of human diseases

Recent research by investigators from deCODE genetics revealed how proteins drastically enhance the understanding of human diseases.

7 Dec 2021

Researchers find that the VCP/p97 protein unfolds, separates other protein structures

Thanks to an old needlework trick that a protein in the human body is aware of, rather than threading yarn into the eye from the end, it could be simpler to pass a loop through it.

2 Dec 2021

Study unearths novel mechanism coordinating the assembly of cell components

A group of researchers recently unearthed vital information on how gene expression is orchestrated.

2 Dec 2021

Deep learning can generate real insights into how proteins interact

Scientist are now combining recent advances in evolutionary analysis and deep learning to build three-dimensional models of how most proteins in eukaryotes interact.

23 Nov 2021

Scientists use AI and evolutionary analysis to produce 3D models of eukaryotic protein interactions

UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions.

17 Nov 2021

Novel technique enhances the predictability of protein manufacturing

Researchers from VIB and Ghent University devised a new technique to analyze the secretability of hundreds of thousands of protein sequences at once.

10 Nov 2021

Experts determine the molecular structure of a gut protein

Researchers from EMBL Hamburg and the Centre for Structural Systems Biology (CSSB) identified the molecular structure of a gut protein that aids the absorption of various drugs. This finding can help produce drugs that reach target tissues more effectively.

8 Nov 2021

Study employs AI to comprehend sugar surrounding proteins in the human body

Novel studies on artificial intelligence (AI) algorithms facilitated researchers to develop more complete models of the protein structures in human bodies.

8 Nov 2021

Researchers predict protein binding based on shape using fastest supercomputer

Proteins attach to one another through a complex mixture of chemical interactions, but what if the process is simpler—like binding due to their shapes?

8 Nov 2021

Simultaneously Measuring 7,000 Proteins: Groundbreaking Proteomics from SomaLogic

In this interview, we speak to Roy Smythe, CEO of SomaLogic, about their groundbreaking proteomics technology that can simultaneously measure 7,000 proteins.

From SomaLogic 4 Nov 2021

Researchers develop new approach to selectively turn on gene therapies in target cells

Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences in cells, and that detection then triggers production of a specific protein from a transgene, or artificial gene.

From Massachusetts Institute of Technology (MIT) 29 Oct 2021

Discovery of long-lived mitochondrial proteins reveals increased stability of the electron transport chain

Mitochondria are known as the powerhouses of the cell, generating the energy that's needed to fuel the functions that our cells carry out.

29 Oct 2021

New eToeholds could make RNA therapeutics more safer and effective

RNAs are best known as the molecules that translate information encoded in genes into proteins with their myriad of activities.

29 Oct 2021

Low dose of pollutants in food leads to high activation of antibodies that cause allergic response

Exposure to the heavy metal cadmium is known to irritate the stomach and lungs or cause kidney disease, but new research links another health issue to inadvertently ingesting low doses of the pollutant: high activation of the antibodies that cause an allergic response.

27 Oct 2021

Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Parkinson's disease (PD) is the most common neurodegenerative movement disorder, afflicting more than 10 million people worldwide and more than one million Americans. While there is no cure for PD, current therapies focus on treating motor symptoms and fail to reverse, or even address, the underlying neurological damage.

26 Oct 2021

Scientists use DNA to create what may be the world's tiniest ruler for measuring proteins

As scientists have probed the mysteries of life down to smaller and smaller scales, they have invented tools to help them understand what they observe.

22 Oct 2021

Viral diseases likely to contribute to neurodegeneration, says study

Scientists from DZNE revealed that certain viral diseases can contribute to neurodegeneration.

21 Oct 2021

Neuroinflammation protein associated with sex-specific survival differences in glioblastoma patients

Scientists have discovered a new link that could bring the scientific and medical community closer to understanding why glioblastoma, the most common malignant brain tumor, is deadlier in males than females.

19 Oct 2021

Researchers map proteo-genomic connections between different human diseases

Hundreds of connections between different human diseases have been uncovered through their shared origin in our genome by an international research team led by scientists from the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge, challenging the categorisation of diseases by organ, symptoms, or clinical speciality.

18 Oct 2021

Research reveals involvement of secretory granules in Parkinson’s disease

Recent research states that the number of secretory granules (SGs) in tyrosine hydroxylase-positive neurons and the marker proteins secretogranin III substantially lowered in the substantia nigra and striatum regions of mice exposed to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine.

13 Oct 2021

Proteomics

Massive study on plasma proteome enhances understanding of human diseases

Researchers find that the VCP/p97 protein unfolds, separates other protein structures

Study unearths novel mechanism coordinating the assembly of cell components

Deep learning can generate real insights into how proteins interact

Scientists use AI and evolutionary analysis to produce 3D models of eukaryotic protein interactions

Novel technique enhances the predictability of protein manufacturing

Experts determine the molecular structure of a gut protein

Study employs AI to comprehend sugar surrounding proteins in the human body

Researchers predict protein binding based on shape using fastest supercomputer

Simultaneously Measuring 7,000 Proteins: Groundbreaking Proteomics from SomaLogic

Researchers develop new approach to selectively turn on gene therapies in target cells

Discovery of long-lived mitochondrial proteins reveals increased stability of the electron transport chain

New eToeholds could make RNA therapeutics more safer and effective

Low dose of pollutants in food leads to high activation of antibodies that cause allergic response

Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Scientists use DNA to create what may be the world's tiniest ruler for measuring proteins

Viral diseases likely to contribute to neurodegeneration, says study

Neuroinflammation protein associated with sex-specific survival differences in glioblastoma patients

Researchers map proteo-genomic connections between different human diseases

Research reveals involvement of secretory granules in Parkinson’s disease

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