Proteomics

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RNA Binding Proteins and EVs Offer Clues to Cancer's Evasion of Immune Response

Certain types of biochemical processes can impair the immune system's ability to recognize and kill cancer cells. Purdue University's W. Andy Tao and his associates have developed a new way to study these processes.

27 Aug 2025

Scientists Use Single-Cell Proteomics to Track Blood Cell Differentiation

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through the course of health or disease.

25 Aug 2025

New Technology Maps Over 140 Proteins Across Human Tissues

Each organ in the human body contains different types of cells arranged in specific ways.

20 Aug 2025

MIT Researchers Unlock the Hidden Features of Protein Language Models

Within the past few years, models that can predict the structure or function of proteins have been widely used for a variety of biological applications, such as identifying drug targets and designing new therapeutic antibodies.

20 Aug 2025

Atomic-Level Models Reveal New Class Of Protein Misfolding

New computer simulations that model every atom of a protein as it folds into its final three-dimensional form support the existence of a recently identified type of protein misfolding.

11 Aug 2025

Integrating Microfluidics and Mass Spectrometry to Unlock Cellular Complexity

Understanding cellular heterogeneity is essential for deciphering the complexities of cellular subpopulations, differentiation processes, and microenvironmental influences.

8 Aug 2025

Salk Scientists Use CRISPR to Uncover Microproteins Linked to Obesity

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide.

8 Aug 2025

New PCE Systems Enable Precise Genome Engineering Across Kilobase to Megabase Scales

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.

5 Aug 2025

AI Tool Accelerates Hunt for Elusive Genome‐Encoded Microproteins

Proteins sustain life as we know it, serving many important structural and functional roles throughout the body.

1 Aug 2025

Stability in Proteins Is More Like Lego Than Jenga

Proteins are life's molecular workhorses, doing everything from turning sunlight into food to fighting viruses.

29 Jul 2025

GlycoPro Platform Enhances High-Throughput Glycosylation Analysis

A recent study published in Engineering introduces GlycoPro, a novel high-throughput sample-processing platform that aims to transform the field of multi-glycosylation-omics analysis.

18 Jul 2025

New Research Highlights Vascular Role in Alzheimer’s

The Aβ/fibrinogen complex is implicated in Alzheimer's progression, highlighting vascular health's role and offering new avenues for therapeutic intervention.

23 Jun 2025

New Frontier in Combating Musculoskeletal Aging Through Exercise

Study identifies CLCF1 as a key protein in exercise, enhancing muscle strength and bone density, and providing a biological basis for aging effects on fitness.

23 Jun 2025

Novel Strategy for Combating High-Fat Diet-Induced Metabolic Dysfunction

Research on receptor FFA2 reveals how different activators influence metabolic processes, paving the way for innovative treatments for diabetes and obesity.

20 Jun 2025

Novel Tool moPepGen Uncovers Hidden Genetic Variants at the Protein Level

Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.

17 Jun 2025

Targeting iRhom2 to Control ADAM17-Related Diseases

The atomic structures of ADAM17 and iRhom2, revealed by UC researchers, offer new avenues for developing precise treatments for chronic inflammatory conditions.

16 Jun 2025

Femtosecond Crystallography Reveals Cryptochrome Mechanisms

Research on cryptochromes using femtosecond crystallography uncovers rapid structural changes, enhancing our understanding of light-driven biological processes.

11 Jun 2025

Proteomic Signature in Blood Predicts Dementia and Diabetes Risk

A blood-based proteomic signature predicts healthspan, linking protein levels to disease risk and mortality, paving the way for targeted aging interventions.

10 Jun 2025

Novel Peptide Shows Promise in Fighting Deadly, Drug-Resistant Bacteria

A study identifies a new antimicrobial peptide that effectively targets gram-negative bacteria, highlighting its potential in combating antibiotic resistance.

5 Jun 2025

Study Reveals Key Proteins Behind CAR-T Cell Therapy Effectiveness

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).

4 Jun 2025