Proteomics

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Csx28 Membrane Protein Enhances CRISPR's Anti-Viral Defense

CRISPR achieved scientific popularity for its capacity to quickly and precisely edit genes. At the core, however, CRISPR systems are immune systems that aid bacteria to safeguard themselves from viruses through targeting and abolishing viral RNA and DNA.

28 Apr 2023

Membrane-Remodeling Proteins in Cyanobacteria are Similar to Protein Found in Higher Organisms

The cells of living organisms are equipped with proteins that are involved in the shaping and remodeling of cellular membranes, thereby performing important tasks.

26 Apr 2023

Study Uncovers a Protein-Protein Interaction Related to Parkinson's Disease

In a study published in Nature Communications, a team led by Krembil Brain Institute Senior Scientists, Drs. Lorraine Kalia and Suneil Kalia, and University of Toronto (U of T) Professor, Dr. Philip M. Kim, identified a protein-protein interaction that contributes to Parkinson's disease.

24 Apr 2023

New Method Uses Light to Activate Protein Functions

Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail.

18 Apr 2023

Comparison of De Novo Proteins and Computer-Generated Proteins

Proteins are components of every cell. How they have changed in the course of evolution for the purpose of taking on new functions in the body, has long been a subject of research.

13 Apr 2023

Evolutionary Encounter of Two Protein Components Could Occur Entirely by Chance

Proteins are the key players for virtually all molecular processes within the cell. To fulfil their diverse functions, they have to interact with other proteins.

7 Apr 2023

Study Paves the Way to Targeted Treatments for Stargardt Disease

A recent study in the Journal of Biological Chemistry revealed the key to a protein that commonly causes blindness.

5 Apr 2023

Identification of Unique Proteins That Might be Body Weight Regulators

Genetic factors may account for up to 50% of the diversity in body mass index, or BMI, in the population.

5 Apr 2023

DELLA Proteins: The Road to the Next Green Revolution

Despite being largely unchanged for over 450 million years, a family of “promiscuous” proteins that are present in all land plants is responsible for a wide range of plant activities.

5 Apr 2023

Experts Unravel the Crystal Structure of CENP-E

Anticancer drugs are essential in cancer treatment, but their toxicity is not always restricted to cancer cells, resulting in serious side effects.

5 Apr 2023

Vegan protein helps develop muscle just as well as animal protein

According to recent research from the University of Exeter, fungi-derived mycoprotein is just as efficient as animal protein in promoting muscle growth during resistance training.

From University of Exeter 5 Apr 2023

Insights into mechanisms impacting NSCLC disease progression

Proteomics is the study and analysis of proteins in a biological system, including their structures, functions, associations, and alterations.

5 Apr 2023

Revealing how cohesin attaches to the DNA and forms loops

Ana Losada, a scientist at the Spanish National Cancer Research Centre (CNIO) and then at the Cold Spring Harbor Laboratory, identified cohesin, a protein essential to the process of cell division, in Xenopus frogs at the end of the 1990s.

5 Apr 2023

Cold Temperature Increases Human Life Expectancy

Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging.

4 Apr 2023

MET+LEU Cocktail Prevents Cellular Senescence and Disrupted Proteostasis Induced by Myotube Atrophy

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 6, entitled, "Cellular senescence and disrupted proteostasis induced by myotube atrophy are prevented with low-dose metformin and leucine cocktail."

3 Apr 2023

Researchers Uncover a New, Direction-Dependent Friction in Proteins

An interdisciplinary research team of the Institutes of Physical Chemistry and Physics of the University of Freiburg and the Max Planck Institute of Biophysics in Frankfurt-am-Main has discovered a new, direction-dependent friction in proteins called anisotropic friction.

3 Apr 2023

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have harnessed a natural bacterial system to develop a new protein delivery approach that works in human cells and animals.

30 Mar 2023

Analyzing the GmZF351 transgenic soybean plants and their stress tolerance

Across the globe, soybean is considered to be an important food, oil, and feed crop worldwide.

29 Mar 2023

New project addresses the lack of standards for optimal management of Lp(a)

According to a recent scientific statement gathered from American Heart Association, high levels of lipoprotein(a) [Lp(a)] are known to be a separate, chiefly inherited and causal risk factor for cardiovascular disease, known to be the leading cause of death and disability around the world.

29 Mar 2023

Determining the structure of protein pumps using cryo-EM

A rare, genetic disorder known as Hailey-Hailey disease causes patches of blisters to develop mainly in the folds of skin under the breasts, in the groin, and the armpits.

29 Mar 2023