Proteomics

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Unraveling the Mysteries of COPII-Mediated Protein Transport

Similar to postal workers who deliver packages in inclement weather, such as snow, rain, or heat waves, a vital set of proteins found in mammals enables cells to operate normally, even in less-than-ideal circumstances.

4 Jan 2024

Scientists Crack the Code for Artificial DNA

The genetic code is composed of just four letters representing the four nucleotides, which are the fundamental building blocks of DNA.

14 Dec 2023

Deciphering the Chemistry Behind Antibody Tetramerization

Novel insights into antibody aggregation are anticipated to pave the way for fresh avenues in both research and therapeutic applications.

11 Dec 2023

Prion Protein Forms Dynamic Liquid Condensates to Regulate Copper Ions

In an innovative research article published in Science Advances, scientists from the Federal University of Rio de Janeiro (UFRJ) and the German Center for Neurodegenerative Diseases (DZNE-Berlin) illuminate the intricate interplay between the prion protein and copper ions in the physiopathology of live cells.

4 Dec 2023

New Irreversible Inhibitor Overcomes Drug Resistance in Cancer Cells

The concept of irreversible inhibitors binding permanently to a target protein has garnered growing interest for potential applications in drug development.

30 Nov 2023

Unraveling the Mystery of L-Cry: A Distinctive Cryptochrome Protein

In a recent release in Nature Communications, a collaborative research group comprising Johannes Gutenberg University Mainz (JGU), the University of Cologne, and the University of Oldenburg has disclosed their discoveries regarding the operation of a distinctive cryptochrome protein (Cry).

16 Nov 2023

Study Identifies Significant Changes in Peptides During Pyroglutamination

Peptides are biomolecules formed when two or more amino acids that perform key functions in the human organism, such as hormones, neurotransmitters, painkillers and antibiotics, bind together. For this reason, they are much studied and used by the pharmaceutical industry, for example.

2 Nov 2023

Novel Activation Mechanism for First Identified Oncogene

In the late 1970s, the link between the c-Src gene and cancer was unveiled, marking the identification of the inaugural oncogene.

1 Nov 2023

Unlocking the Mystery of N-Terminal Acetylation’s Impact on Protein Degradation

Scientists at the University of Bergen (UiB) have discovered that proteins employ a shared chemical marker as a protective shield against degradation, thereby influencing their mobility and the aging process.

30 Oct 2023

Researchers Unveil Novel Protein Families and Functions in Microbial Communities

Imagine researchers exploring a dark room with a flashlight, only able to clearly identify what falls within that single beam. When it comes to microbial communities, scientists have historically been unable to see beyond the beam -; worse, they didn't even know how big the room is.

12 Oct 2023

Research Develops a Comprehensive Spatial Atlas of Proteins in the Chloroplast

Plants and algae convert solar energy into chemical energy through photosynthesis. This process is vital for life on Earth and provides us with oxygen, food, fuels, and other valuable products.

6 Oct 2023

Ancient Feathers Had a Similar Protein Composition to Modern Feathers

Paleontologists from the University College Cork (UCC) in Ireland have made a remarkable discovery using X-Ray technology that offers fresh insights into the evolution of feathers.

22 Sep 2023

The Final Piece Required for Easy Protein Sequencing

The development of technology that makes protein sequencing simple has been the focus of an actual race among scientists.

19 Sep 2023

Shaping Proteins in Parallel Alignment with Hydrophobicity

Biological molecules self-assemble into huge functional structures that sustain life’s fundamental processes through a delicate balance of electrical and hydrophobic forces.

4 Sep 2023

Processed Foods May Lead to Obesity by Diluting Protein

Humans, like so many other species, control protein intake more strictly than any other dietary component, so if protein intake is reduced, food intake increases to make up for it.

4 Sep 2023

Versatile, Language-Based Approach Aids in the Design of New Proteins

Researchers discovered a new type of marine bacteria with distinct traits on the ocean floor.

30 Aug 2023

Scientists Uncover New Mechanism for Degrading Short-Lived Proteins

Short-lived proteins control gene expression in cells to carry out a number of vital tasks, from helping the brain form connections to helping the body mount an immune defense. These proteins are made in the nucleus and are quickly destroyed once they've done their job.

25 Aug 2023

Protein Analysis of Ancient Cauldrons Reveals Diet of Caucasus People

Archaeologists have long been drawing conclusions about how ancient tools were used by the people who crafted them based on written records and context clues.

21 Aug 2023

Noelin1-3 Proteins Have Major Influence on Learning and Memory Formation in the Mammalian Brain

A German-American research team headed by Prof. Dr. Bernd Fakler from the Faculty of Medicine at the University of Freiburg demonstrated the major influence of Noelin1-3 proteins on learning and memory formation in the mammalian brain.

21 Aug 2023

Noelin Proteins’ Key Role in Strengthening Neuronal Signals

As per a research study in mice from the National Eye Institute (NEI) and the University of Freiberg, Germany, the Noelin family belonging to secreted proteins bind to the exterior part of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane.

17 Aug 2023