Analytical Chemistry News and Research

Latest Analytical Chemistry News and Research

Fragment-Based Drug Design Accelerates Efficient Discovery of New Medicines

Modern medicine has played a significant role in improving the length and quality of our lives. While many treatments may seem like miracles, they are the result of a lengthy, rigorous research process.

24 Apr 2026

New Study Uncovers Previously Undetected Form of DNA Damage

In everyday life, our genetic material is constantly under attack from many factors. Environmental influences such as light, along with internal processes like inflammation, can generate oxidative stress that damages DNA and its downstream partner, RNA, which can lead to faster aging and diseases such as cancer.

24 Apr 2026

Uncovering a Second Pathway for On-Demand Glycogen Regulation

Researchers at WEHI have uncovered a never-before-seen mechanism that human bodies utilize to control sugar. These discoveries redefine basic biological principles and pave the way for new scientific discoveries.

24 Apr 2026

Protein Shape Changes Come Into Focus With LiP-MS and 3D Proteomics

This review explains how LiP-MS detects protein structural changes across whole proteomes, adding functional insight that standard abundance-based proteomics often misses. It also surveys method variants and shows how LiP-MS supports drug-target discovery, disease biomarker research, and the broader framework of “3D proteomics.”

20 Apr 2026

Next-Generation Mass Spectrometry Reveals How DIA Deepens Proteome Coverage

A multivendor comparison in a neonatal mouse model of bronchopulmonary dysplasia found that DIA, especially on next-generation platforms such as Orbitrap Astral and timsTOF Ultra, greatly expanded peptide and protein detection while preserving broad biological concordance. The deeper coverage improved subcellular and pathway annotation, increased differential protein detection, and reduced estimated sample-size needs, although platform-specific technical differences still complicated direct comparisons.

19 Apr 2026

Scientists Uncover How "Sorting Hubs" Clear Damaged Proteins From Cells

Inside every cell, a cleanup operation runs around the clock. Proteins are constantly damaged by wear and tear. Some can be repaired, while others must be dismantled and recycled. When this system fails, damaged proteins accumulate in clumps associated with diseases such as Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia.

16 Apr 2026

How Single-Cell Proteomics Could Unlock the Rules That Govern Cells

This review shows how single-cell proteomics by mass spectrometry has advanced from an uncertain idea to a rapidly improving toolkit that can now quantify thousands of protein groups from individual cells. It argues that direct protein measurements, combined with better sample preparation, instrumentation, and multiplexing, could help researchers build more mechanistic models of cell biology while pushing throughput far higher.

13 Apr 2026

A Python-Inspired Molecule Suppresses Appetite After Eating

The study identifies pTOS as a key metabolite in appetite suppression, highlighting a gut–liver–brain pathway with implications for obesity therapy.

2 Apr 2026

Discovery Challenges the Theory That Proteins Move Mainly by Diffusion

Scientists at Oregon Health & Science University have uncovered a previously unknown system of internal "trade winds" that help cells rapidly move essential proteins to the front of the cell, reshaping how researchers understand cell migration, cancer spread and wound healing.

31 Mar 2026

Shimadzu’s Design Craftech - Fusing Traditional Kyoto Craft Techniques with Industrial Production

Shimadzu Corporation, which was celebrating its 150th anniversary in 2025, has a long history of involvement with traditional Kyoto crafts dating back to its origins as a maker of Buddhist altar fittings.

From Shimadzu Europa GmbH 27 Mar 2026