Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

Scientists Discover New Class of Molecular Glue Degraders for Cancer Therapy

Cells contain molecular machinery that targets and disposes of unwanted proteins to maintain homeostasis.

17 Nov 2023

Gene Splicing Affects CD20 Expression and Response to Cancer Immunotherapy

Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated.

17 Nov 2023

Study Uncovers Ancestry-Specific Genetic Factors in IBD

The advent of whole genome sequencing technology has prompted an explosion in research into how genetics are associated with disease risk.

17 Nov 2023

New Model Reveals How Cells Maintain Epigenetic Memory During Cell Division

Every cell in the human body contains the same genetic instructions, encoded in its DNA. However, out of about 30,000 genes, each cell expresses only those genes that it needs to become a nerve cell, immune cell, or any of the other hundreds of cell types in the body.

17 Nov 2023

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

17 Nov 2023

A Surprising Control Mechanism of Chlamydomonas Cell Division

Headed by James Umen, PhD, a team of international researchers at the Donald Danforth Plant Science Center has uncovered a surprising revelation about the single-celled green alga Chlamydomonas and its control over cell division.

16 Nov 2023

More Genes Changed By Early Life Stress Than Head Injury

Researchers recently discovered a phenomenon as they delved into the investigation of whether early-life stress exacerbates the impact of a childhood head injury on health and behavior in later years.

16 Nov 2023

Tokyo Metropolitan University Decodes DNA Repair Mechanisms

Tokyo Metropolitan University researchers have uncovered crucial aspects of the DNA repair mechanism within human bodies.

16 Nov 2023

Northwestern University’s Deep Dive into Yucatán’s Underwater Labyrinth

Assisted by an adept underwater cave-diving team, scientists from Northwestern University have meticulously charted the most comprehensive map to date of microbial communities inhabiting the submerged mazes beneath Mexico’s Yucatán Peninsula.

16 Nov 2023

Circular Extrachromosomal DNA Linked to Medulloblastoma Relapse and Death

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA-;loops of DNA found outside of regular chromosomes-;are twice as likely to relapse and three times as likely to die within five years of diagnosis.

15 Nov 2023

Cancer Stem Cells Induce Macrophage Senescence, Creating Conditions for Tumor Formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

15 Nov 2023

Study Sheds Light on Factors Contributing to Low-Level Viremia in HIV Patients

Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them.

15 Nov 2023

Rare Genetic Variant Found to Protect Against Alzheimer's Disease

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

14 Nov 2023

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.

14 Nov 2023

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

14 Nov 2023

LJI Scientists Uncover New Superpower of MAIT Cells

Scientists at La Jolla Institute for Immunology (LJI) are investigating a talented type of T cell.

13 Nov 2023

Quantum Biology and AI Improve CRISPR Cas9 Efficiency in Microbes

Scientists at Oak Ridge National Laboratory used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

10 Nov 2023

New Synthetic Enzymes can Control Signaling Protein Vital to Embryonic Development

A University of Texas at Dallas bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos.

10 Nov 2023

Large Study Finds 187 New Genetic Variants Linked to Prostate Cancer

A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk -; 451 in all -; through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet.

10 Nov 2023

Dissecting the Mechanisms Behind Selective Genomic Editing

A new study is in progress to unravel a fascinating biological mystery of how certain animals can naturally eliminate more than half of their genetic information during embryonic development.

10 Nov 2023