Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

Study Reveals T Cell Plasticity as a Key Driver of Systemic Autoimmunity

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.

5 May 2025

New Gene Editing Tool Alters Mitochondrial Mutation Levels in Stem Cells

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes.

5 May 2025

Tracheal Basal Cells Identified as Origin of Lung Squamous Cell Carcinoma

The 'cell of origin' of the second most common lung cancer and the way that it becomes dominant in the lung have been discovered, in a new study in mice and humans from researchers at UCL, the Wellcome Sanger Institute and the University of Cambridge.

2 May 2025

Dr. Jeremy Poschmann’s data-driven approach to immune profiling and translational science

Dr. Jeremy Poschmann discusses data-driven approaches in genomics, revealing how immune profiling can predict disease risk and improve patient outcomes.

1 May 2025

Enhanced Stem Cell Sorting Method Boosts Cultured Meat Potential

By optimizing cell surface marker combinations, the study significantly improves stem cell purity and myogenic potential during passaging, offering a robust source of seed cells essential for advancing cultured meat technologies.

30 Apr 2025

Single DNA Mutation Dysregulates Key Tumor-Suppressing Pathways in Blood Cancer

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumor-suppressing pathways, opening up new avenues for blood cancer treatment.

30 Apr 2025

Genetic Diversity in Wild Rice Offers Clues for Crop Improvement

A new study, seen in Nature Genetics and led by researchers at King Abdullah University of Science and Technology (KAUST; Saudi Arabia) and Wageningen University & Research (the Netherlands), provides new insights on rice evolution, showing how the DNA of this valuable crop has changed across species.

29 Apr 2025

Reciprocal Regulatory Link Between ecDNA Maintenance and DNA Damage Response Revealed

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes.

29 Apr 2025

New Genetic Discoveries Offer Hope for Osteoarthritis Treatments

Researchers have uncovered multiple new genes and genetic pathways that could lead to repurposing hundreds of existing drugs for osteoarthritis, the most common form of arthritis.

29 Apr 2025

New Pangenome Analysis Uncovers Genetic Key to Larger Peanut Yields

Researchers from Australia and China have identified crucial structural variations that determine seed size and weight in peanuts, paving the way for the development of higher-yielding crop varieties.

29 Apr 2025

Chimpanzee Naive Stem Cells Reveal Evolutionary Clues to Human Development

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology.

29 Apr 2025

New Drug Combo Shows Promise Against Aggressive Leukemia in Landmark Study

A novel drug combination targeting LSD1 and GSK3 shows promise in treating acute myeloid leukemia by promoting cell differentiation and reducing tumor growth.

28 Apr 2025

Super Stem Cells Offer New Hope for IVF and Regenerative Medicine

The ‘super stem cells’ perform better than regular stem cells, being able to develop into many different cell types, researchers from the University of Copenhagen find, with many potential applications, including improved IVF treatment.

25 Apr 2025

Unraveling the Role of Long Noncoding RNAs in the Tumor Microenvironment

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting to influence tumorigenesis, progression, and metastasis.

25 Apr 2025

Transitioning Pancreatic Cells Retain Cancer Linked Epigenetic Marks

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a temporary "memory" of those cancer-linked marks.

25 Apr 2025