Microscopy News and Research

Latest Microscopy News and Research

A Previously Unknown Mechanism for DNA Folding Revealed

A hitherto unknown mechanism for DNA folding is described in a study in Nature published by researchers from Karolinska Institutet and the Max Planck Institute for Biophysics.

20 Apr 2023

Augmenting Anatomical EM Images with Multiplexed Gene Expression Maps

Special reporter proteins created by a research team guided by the Technical University of Munich may now aid in molecular discovery.

19 Apr 2023

Two Molecular Mechanisms Combine to Make the Bacterium Extra Resistant

When the intestinal flora is killed by antibiotics, a species of ordinary gut bacteria that humans carry flourishes. Because the bacteria are naturally immune to many drugs, it poses complications, especially in healthcare settings.

18 Apr 2023

Scientists Develop AI-Based Method for Virtual Staining of Histopathological Tissues

Researchers from the University of Eastern Finland, the University of Turku, and Tampere University have developed an artificial intelligence-based method for virtual staining of histopathological tissue samples as a part of the Nordic ABCAP consortium.

17 Apr 2023

Entry of Aging-Associated Enzymes into Human Genetic Material

An enzyme that controls aging and other metabolic processes accesses human genetic material to modify gene expression within the cell, according to a new study. Images of a sirtuin enzyme bound to a nucleosome, a tightly packed complex of DNA and proteins called histones, have been created by a team led by Penn State researchers.

17 Apr 2023

Tiny Protein Interacts with Ion Channels to Make Our Eyes Sensitive to Dim Light

Using cryo-electron microscopy and mass spectrometry, researchers from PSI have deciphered the structure of an ion channel found in the eye while it interacts with the protein calmodulin – a structure that has eluded scientists for three decades.

4 Apr 2023

Researchers Explain How a Single Mutation Causes Ataxia

Worldwide, only a handful of patients are known to suffer from episodic ataxia type 6, a neurological disease that causes transient loss of muscle control.

4 Apr 2023

Researchers Uncover a New, Direction-Dependent Friction in Proteins

An interdisciplinary research team of the Institutes of Physical Chemistry and Physics of the University of Freiburg and the Max Planck Institute of Biophysics in Frankfurt-am-Main has discovered a new, direction-dependent friction in proteins called anisotropic friction.

3 Apr 2023

New, Effective Method can Make Rare Cell Types and Disease Patterns Visible in Tissue

The human body contains more than 30 trillion cells. Until recently, the sheer number of cells in the organism meant that approaches to understanding human diseases and developmental processes based on the analysis of single cells were a futuristic vision.

3 Apr 2023

CrestOptics Launches CICERO System to Provide All-in-One Solution for Widefield and Spinning Disk Confocal Microscopy

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, today announced the launch of its new spinning disk confocal microscope system, CICERO.

3 Apr 2023

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

Shigella bacteria can infect humans but not mice. In the March 29 issue of Nature, a team from UConn Health explains why. Their findings may explain the multifariousness of a key weapon of our immune system.

31 Mar 2023

The proper implementation of stem cell-based disease models

Scientists have learned how to manufacture induced pluripotent stem cells (iPSC) from regular cells through genetic reprogramming during the last ten years.

29 Mar 2023

Determining the structure of protein pumps using cryo-EM

A rare, genetic disorder known as Hailey-Hailey disease causes patches of blisters to develop mainly in the folds of skin under the breasts, in the groin, and the armpits.

29 Mar 2023

Human cells shed light on basic squid biology

Squids and octopuses are masters of camouflage, blending into their environment to evade predators or surprise prey.

28 Mar 2023

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

One of the ways that cancer cells hide from the body's immune system is by forming a thin surface barrier called the glycocalyx.

27 Mar 2023

Understanding the cellular effects of antibiotics targeting cell wall biosynthesis

It is still unclear how antibiotics work to destroy bacteria. This knowledge, however, is required for the development of new antibiotics. That is exactly what is required because bacteria are becoming increasingly resistant to existing antibiotics.

27 Mar 2023

Effective encoding strategy streamlines the handling and storage of single-cell data

Single-cell analysis is an effective biomedical technique used to identify unusual cell populations, monitor cell development and differentiation, comprehend disease causes, and design individualized therapies, but it generates massive amounts of data that can be challenging to handle.

23 Mar 2023

The protein synthesis mechanism in the Giardia parasite

Cryo-electron microscopy was employed by Uppsala University researchers to reveal information on the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhea. The new findings could help in the development of specific medicines to combat Giardia and other protozoan parasites.

20 Mar 2023

New antibody "cocktail" may help counter the Lassa virus

The finding, made with the use of the Advanced Photon Source, shows a new way to exploit monoclonal antibodies to subvert the "shield" of the virus, potentially paving the way for new therapies.

20 Mar 2023

Using PET and electron microscopy to generate 3D maps of mitochondrial networks in lung tumors

Scientists have long known that mitochondria, the "powerhouses" of cells, play a crucial role in the metabolism and energy production of cancer cells.

16 Mar 2023

Microscopy News and Research

Latest Microscopy News and Research

A Previously Unknown Mechanism for DNA Folding Revealed

Augmenting Anatomical EM Images with Multiplexed Gene Expression Maps

Two Molecular Mechanisms Combine to Make the Bacterium Extra Resistant

Scientists Develop AI-Based Method for Virtual Staining of Histopathological Tissues

Entry of Aging-Associated Enzymes into Human Genetic Material

Tiny Protein Interacts with Ion Channels to Make Our Eyes Sensitive to Dim Light

Researchers Explain How a Single Mutation Causes Ataxia

Researchers Uncover a New, Direction-Dependent Friction in Proteins

New, Effective Method can Make Rare Cell Types and Disease Patterns Visible in Tissue

CrestOptics Launches CICERO System to Provide All-in-One Solution for Widefield and Spinning Disk Confocal Microscopy

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

The proper implementation of stem cell-based disease models

Determining the structure of protein pumps using cryo-EM

Human cells shed light on basic squid biology

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

Understanding the cellular effects of antibiotics targeting cell wall biosynthesis

Effective encoding strategy streamlines the handling and storage of single-cell data

The protein synthesis mechanism in the Giardia parasite

New antibody "cocktail" may help counter the Lassa virus

Using PET and electron microscopy to generate 3D maps of mitochondrial networks in lung tumors

Life Science Microscopy eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Microscopy News and Research

Latest Microscopy News and Research

Life Science Microscopy eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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