Microscopy News and Research

Latest Microscopy News and Research

Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

In new research, UT Southwestern scientists report that imaging a key immunity protein known as STING at near-atomic resolution reveals a previously undiscovered binding location that appears to be crucial for launching immunological attacks.

11 Apr 2022

Combining organoids and microfluidics to study how the immune system responds to hepatitis C

A vaccine for hepatitis C has eluded scientists for more than 30 years, for several reasons. For one, the virus that causes the disease comes in many genetic forms, complicating the creation of a widely effective vaccine.

7 Apr 2022

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

7 Apr 2022

New technique for better visualizing the CNS fibroblasts

The central nervous system (CNS) consists of several types of cells having varied specialized functions.

7 Apr 2022

Checkpoint immunotherapy acts as an interface between killer T cells and dendritic cells

Chronic viral infections and cancers can damage the immune system permanently, diminishing the ability of immune killer T cells to destroy tumor cells or virus-infected cells—a condition known as “immune exhaustion.”

5 Apr 2022

Researchers explore a new procedure to disrupt gene regulation

What role does DNA packing play in regulating gene activity? Fanka Rang and Kim de Luca, researchers from Jop Kind’s (group leader at the Hubrecht Institute and Oncode Investigator) group, created a way to monitor both gene activity and DNA packaging at the same time to address this topic.

5 Apr 2022

Noncoding DNA mutations prevent the brain from amyotrophic lateral sclerosis

When a condition is connected to a genetic mutation, it is generally negative news.

4 Apr 2022

Researchers discover a unique technique to fight hospital-borne disease

A study team developed an early-stage therapy that sabotages the pump and restores antibiotic efficiency by disclosing the structure of a protein needed by bacteria to pump out antibiotics.

4 Apr 2022

Research reveals how a building block protein assembles to form poxvirus scaffold

Researchers at the Okinawa Institute of Science and Technology Graduate University have revealed how poxviruses build their scaffold - a temporary protein coat that forms and disappears as the virus matures.

1 Apr 2022

Plant biologists determine molecular ‘blueprint’, showing how plants observe light

For survival, plants depend on their ability to detect light. Plants, unlike animals, do not have photoreceptors in their eyes to receive and transmit messages from visual inputs.

1 Apr 2022

Research highlights the factors needed to reprogramme naïve pluripotent stem cells

Following a genome-wide functional screen, scientists from the Babraham Institute’s Epigenetics research department were able to learn more about naïve stem cell reprogramming.

1 Apr 2022

AI and robotics identify new cellular hallmarks of Parkinson's disease

A study published today in Nature Communications unveils a new platform for discovering cellular signatures of disease that integrates robotic systems for studying patient cells with artificial intelligence methods for image analysis.

28 Mar 2022

Multiple nanobodies effectively block infection with different SARS-CoV-2 variants

Researchers at Karolinska Institutet in Sweden have developed a novel strategy for identifying potent miniature antibodies, so-called nanobodies, against emerging SARS-CoV-2 variants.

28 Mar 2022

Cryo-electron microscopes help determine how “911” molecule repairs DNA damage

When something unexpected happens with DNA replication, cells call their own form of 911 to stop the process and rectify the problem.

23 Mar 2022

Scientists reveal how 9-1-1 clamp attaches to DNA damage site for initiating effective repair

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.

22 Mar 2022

Curved shape enables predatory bacteria to efficiently invade, grow and live inside the prey

Scientists have found that a predatory bacterium, capable of invading and consuming harmful bugs such as E.coli and Salmonella, can sculpt its own shape to fit inside its prey.

22 Mar 2022

Specific brain cells in the claustrum of mice control stress-induced anxiety behaviors

It is well known that long-term exposure to stress can lead to serious psychiatric problems. However, the precise mechanisms underpinning the stress response have remained largely elusive.

21 Mar 2022

Study shows the impact of ATP binding in human integrin-linked kinase and cell behavior

Getting from point A to point B might be difficult, especially for mobile cells.

21 Mar 2022

Researchers use GP2 and UMOD to prevent urinary tract infection

A team led by Karolinska Institute used AI and structural biology to learn more about two similar proteins that protect against bacterial infection in the urinary tract.

16 Mar 2022

Cryo-EM reveals how a bacterial protein senses and rescues stalled ribosomes

As a molecular machine found in the cells of all organisms, the ribosome is responsible for making new proteins.

11 Mar 2022

Microscopy News and Research

Latest Microscopy News and Research

Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

Combining organoids and microfluidics to study how the immune system responds to hepatitis C

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

New technique for better visualizing the CNS fibroblasts

Checkpoint immunotherapy acts as an interface between killer T cells and dendritic cells

Researchers explore a new procedure to disrupt gene regulation

Noncoding DNA mutations prevent the brain from amyotrophic lateral sclerosis

Researchers discover a unique technique to fight hospital-borne disease

Research reveals how a building block protein assembles to form poxvirus scaffold

Plant biologists determine molecular ‘blueprint’, showing how plants observe light

Research highlights the factors needed to reprogramme naïve pluripotent stem cells

AI and robotics identify new cellular hallmarks of Parkinson's disease

Multiple nanobodies effectively block infection with different SARS-CoV-2 variants

Cryo-electron microscopes help determine how “911” molecule repairs DNA damage

Scientists reveal how 9-1-1 clamp attaches to DNA damage site for initiating effective repair

Curved shape enables predatory bacteria to efficiently invade, grow and live inside the prey

Specific brain cells in the claustrum of mice control stress-induced anxiety behaviors

Study shows the impact of ATP binding in human integrin-linked kinase and cell behavior

Researchers use GP2 and UMOD to prevent urinary tract infection

Cryo-EM reveals how a bacterial protein senses and rescues stalled ribosomes

Genome Editing Has A New Code

Researchers reveal key developmental difference between the brains of modern humans and Neandertals

Cell Counting Without Slides to Reduce Waste and Cost

Drug Discovery eBook

Microscopy News and Research

Latest Microscopy News and Research

Genome Editing Has A New Code

Researchers reveal key developmental difference between the brains of modern humans and Neandertals

Cell Counting Without Slides to Reduce Waste and Cost

Drug Discovery eBook

Newsletters you may be interested in