Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Study reveals how chloroplast ATP synthase regulates ATP production in organisms

ATP, the compound essential for the functioning of photosynthetic organisms such as plants, algae, and cyanobacteria, is produced by an enzyme called "chloroplast ATP synthase" (CFoCF1).

22 Feb 2023

New host protease determinants facilitating the infection of SARS-CoV-2 identified

Researchers from Department of Microbiology, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified novel host protease determinants, that facilitate the infection of SARS-CoV-2, including the Omicron variant, which provided new targets for combating the pandemic.

22 Feb 2023

New insights into the mechanism underlying the immunomodulatory effects of polyphenols

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

ApoE4 from neurons plays a critical role in Alzheimer's disease

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4.

22 Feb 2023

Fungal symbionts help detect volatile fungal metabolites of host tree resin monoterpenes

The mass outbreaks of bark beetles observed in recent years have caused shocking amounts of forest damage throughout Germany.

22 Feb 2023

Fungal symbionts helps detect volatile fungal metabolites of host tree resin monoterpenes

The mass outbreaks of bark beetles observed in recent years have caused shocking amounts of forest damage throughout Germany.

22 Feb 2023

New biomarker helps identify biological age

Once considered to be incompetent in encoding proteins due to their simple monotonous DNA repetitions, tiny telomeres at the tips of human chromosomes now appear to have a powerful biological function that could help better understand cancer and aging.

21 Feb 2023

Analyzing the existence of unknown miniproteins

Evolutionarily young miniproteins are unique in humans, and scientists have recently found thousands of them.

21 Feb 2023

Toxic protein likely to be the cause of two rare genetic disorders identified

Scientists at the National Institutes of Health and their co-workers reported that DUX4, a toxic protein produced by the body, might just be the reason for two completely different rare genetic disorders.

21 Feb 2023

Novel metabolic pathway that makes immunology more efficient revealed

The metabolic pathways that produce a specific type of T cell are distinct from previously assumed, according to findings from the University of Michigan Rogel Cancer Center.

21 Feb 2023

Accelerating the structure-guided discovery of chemogenetic tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells. One way is by using a tool called DREADDs, which stands for Designer Receptors Activated by Designer Drugs.

21 Feb 2023

Probiotic application shown to promote health and growth of piglets

This study is led by Prof. Heping Zhang (Inner Mongolia Key Laboratory of Dairy Biotechnology and Engineering, Inner Mongolia Agricultural University).

20 Feb 2023

Iron-dependent cell death can be used to improve immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

20 Feb 2023

Novel molecule prevents cells from infection with SARS-COV-2

The virus that causes COVID-19, called SARS-CoV-2, uses its spike protein in order to stick to and infect our cells. The final step for the virus to enter our cells is for part of its spike protein to act like a twist tie, forcing the host cell's outer membrane to fuse with the virus.

20 Feb 2023

Expert releases open-source compilation of the SARS-CoV-2 molecular structure

A biomedical researcher at the Lankenau Institute for Medical Research (LIMR), part of Main Line Health, has created a groundbreaking resource for scientists seeking to develop new and better vaccines in the fight against COVID-19.

19 Feb 2023

CD5-expressing dendritic cells help to prime T cell responses against cancer

Immunotherapy has transformed cancer care. In advanced melanoma, for example, the most fatal form of skin cancer, the five-year survival rate has risen from less than 10% to more than 50% since immunotherapy was introduced in 2011.

17 Feb 2023

"Poisoned" form of a protein could set off events that encourage cancer growth

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers.

17 Feb 2023

Locating genes involved in the metabolism and distribution of human fat

Researchers from the University of Minnesota Medical School and the University of Chicago discovered data identifying “jumping genes”—associated with the distribution of fat in the abdomen—that are connected to a higher risk for health problems from obesity in women.

17 Feb 2023

Improved efficacy of advanced genome editing with machine learning

Researchers at the Wellcome Sanger Institute have developed a new tool to estimate the probability of successfully introducing a gene-edited DNA sequence into a cell’s genome using the prime editing method.

17 Feb 2023

Substituting meat for mycoprotein reduces intestinal genotoxins, increases healthy gut bacteria

Researchers from Northumbria University have found that swapping red and processed meat for Quorn's mycoprotein, a fungi-based meat alternative, leads to a significant reduction in intestinal genotoxins - which can cause bowel cancer - and increases healthy gut bacteria.

17 Feb 2023

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Study reveals how chloroplast ATP synthase regulates ATP production in organisms

New host protease determinants facilitating the infection of SARS-CoV-2 identified

New insights into the mechanism underlying the immunomodulatory effects of polyphenols

ApoE4 from neurons plays a critical role in Alzheimer's disease

Fungal symbionts help detect volatile fungal metabolites of host tree resin monoterpenes

Fungal symbionts helps detect volatile fungal metabolites of host tree resin monoterpenes

New biomarker helps identify biological age

Analyzing the existence of unknown miniproteins

Toxic protein likely to be the cause of two rare genetic disorders identified

Novel metabolic pathway that makes immunology more efficient revealed

Accelerating the structure-guided discovery of chemogenetic tools

Probiotic application shown to promote health and growth of piglets

Iron-dependent cell death can be used to improve immunotherapies against liver cancer

Novel molecule prevents cells from infection with SARS-COV-2

Expert releases open-source compilation of the SARS-CoV-2 molecular structure

CD5-expressing dendritic cells help to prime T cell responses against cancer

"Poisoned" form of a protein could set off events that encourage cancer growth

Locating genes involved in the metabolism and distribution of human fat

Improved efficacy of advanced genome editing with machine learning

Substituting meat for mycoprotein reduces intestinal genotoxins, increases healthy gut bacteria

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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