Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Researchers identify a vital protein needed to regulate anti-tumor immune response

Scientists from The University of Texas MD Anderson Cancer Center have identified a protein known as NF-kappa B-inducing kinase (NIK).

5 Jan 2021

Scientists resolve long-standing debate over key mechanism involved in gene silencing

Scientists from Massachusetts General Hospital (MGH) have resolved a long-standing debate over how crucial gene-silencing protein detects its targets.

5 Jan 2021

Study shows that hemoglobin in several species descends from a single gene

The marine worm Platynereis dumerilii has enabled researchers from CNRS, Université de Paris, Sorbonne Université, University of Saint Petersburg, and the University of Rio de Janeiro to demonstrate that hemoglobin appeared independently in several species and actually evolved from a single gene transmitted to all by their last common ancestor.

4 Jan 2021

Altered sugar composition impacts cell-to-surface adhesion

Biotechnologists measure the forces with which algae cells adhere to surfaces and move on them. How can cells adhere to surfaces and move on them? This is a question that was investigated by an international team of researchers headed by Prof. Michael Hippler from the University of Münster and Prof. Kaiyao Huang from the Institute of Hydrobiology (Chinese Academy of Sciences, Wuhan, China).

4 Jan 2021

Abnormalities in cholesterol transport protein associated with schizophrenia

Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens.

29 Dec 2020

Twist‐and‐squeeze mechanism of transporter protein confers cancer drug resistance

In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences, discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of some cancer cells, making them resistant to treatment. How it did this has remained a mystery for the past 35 years.

29 Dec 2020

Study reveals evolutionary relationship between two different organelles in liverwort cells

Cells, the basic unit of life, are surrounded by a limiting membrane called the plasma membrane. Inside cells, there are various membrane-bounded organelles, each of which has various and distinctive functions.

29 Dec 2020

Controlling biological functions of DNA with the aid of light

DNA (deoxyribonucleic acid) is the basis of life on earth. The function of DNA is to store all the genetic information, which an organism needs to develop, function and reproduce. It is essentially a biological instruction manual found in every cell.

29 Dec 2020

Chromosomal instability is associated with cancer's aggressiveness

Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether.

29 Dec 2020

HKU researchers develop new drug discovery strategy targeting membrane proteins on live cells

A research team led by Dr Xiaoyu LI from the Research Division for Chemistry, Faculty of Science, in collaboration with Professor Yizhou LI from School of Pharmaceutical Sciences, Chongqing University and Professor Yan CAO from School of Pharmacy, Second Military Medical University in Shanghai has developed a new drug discovery method targeting membrane proteins on live cells.

29 Dec 2020

High-speed atomic force microscopy sheds light on structure, dynamics of intrinsically disordered proteins

Kanazawa University’s pioneering high-speed atomic force microscope technology has now shed light on the structure and dynamics of some of life’s most ubiquitous and inscrutable molecules – intrinsically disordered proteins.

29 Dec 2020

A protein encourages cell stickiness during development

Tohoku University scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development.

28 Dec 2020

Scientists discover new class of compounds for combating antimicrobial resistance

Wistar Institute scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing of pan drug-resistant bacterial pathogens with a simultaneous rapid immune response for combatting antimicrobial resistance (AMR). These finding were published today in Nature.

24 Dec 2020

Triple drug combination keeps people with metastatic colon cancer disease free for longer time

Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, have shown that a triple drug combination - of irinotecan, cetuximab, and vemurafenib - is a more powerful tumor fighter and keeps people with metastatic colon cancer disease free for a significantly longer period of time compared with patients treated with irinotecan and cetuximab.

24 Dec 2020

Transporter protein likely played a crucial role in vertebrate evolution

A transporter protein that regulates cell membrane cholesterol likely played an important role in vertebrate evolution, according to a review published by iCeMS researchers in the journal FEBS Letters.

24 Dec 2020

Researchers report a potential cancer drug that targets mitochondrial function

A newly developed compound starves cancer cells by attacking their "power plants" - the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read.

23 Dec 2020

Researchers use different colors of light to control gut bacteria genes

Baylor College of Medicine researcher Meng Wang had already shown that bacteria that make a metabolite called colanic acid (CA) could extend the lifespan of worms in her lab by as much as 50%, but her collaboration with Rice University synthetic biologist Jeffrey Tabor is providing tools to answer the bigger question of how the metabolite imparts longer life.

23 Dec 2020

Scientists discover molecular defects associated with rare genetic disorder in children

Damien D'Amours and his team at the Ottawa Institute of Systems Biology needed three years to discover the molecular defects associated with the LIC Syndrome, a serious genetic disorder that affects young children and result in acute respiratory distress, immune deficiency and abnormal chromosomes.

23 Dec 2020

Scientists find master switch that adjusts gene activity to match nutrient levels in roundworms

Transforming a fertilized egg into a fully functional adult is a complicated task. Cells must divide, move, and mature at specific times. Developmental genes control that process, turning on and off in a choreographed way.

23 Dec 2020

Anti-diarrhea drug could be used to induce cell death in glioblastoma cell lines

The research group led by Dr Sjoerd van Wijk from the Institute of Experimental Cancer Research in Paediatrics at Goethe University already two years ago found evidence indicating that the anti-diarrhea drug loperamide could be used to induce cell death in glioblastoma cell lines.

23 Dec 2020

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Researchers identify a vital protein needed to regulate anti-tumor immune response

Scientists resolve long-standing debate over key mechanism involved in gene silencing

Study shows that hemoglobin in several species descends from a single gene

Altered sugar composition impacts cell-to-surface adhesion

Abnormalities in cholesterol transport protein associated with schizophrenia

Twist‐and‐squeeze mechanism of transporter protein confers cancer drug resistance

Study reveals evolutionary relationship between two different organelles in liverwort cells

Controlling biological functions of DNA with the aid of light

Chromosomal instability is associated with cancer's aggressiveness

HKU researchers develop new drug discovery strategy targeting membrane proteins on live cells

High-speed atomic force microscopy sheds light on structure, dynamics of intrinsically disordered proteins

A protein encourages cell stickiness during development

Scientists discover new class of compounds for combating antimicrobial resistance

Triple drug combination keeps people with metastatic colon cancer disease free for longer time

Transporter protein likely played a crucial role in vertebrate evolution

Researchers report a potential cancer drug that targets mitochondrial function

Researchers use different colors of light to control gut bacteria genes

Scientists discover molecular defects associated with rare genetic disorder in children

Scientists find master switch that adjusts gene activity to match nutrient levels in roundworms

Anti-diarrhea drug could be used to induce cell death in glioblastoma cell lines

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Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Omics eBook

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

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