Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

CSHL Researchers Reveal New Protein Networks in RNA Splicing Regulation

Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes.

11 Jun 2024

CARA Benchmark Set to Revolutionize Data-Driven Drug Discovery Methods

A compound activity prediction benchmark they curated for real-world, practical applications called Compound Activity benchmark for Real-world Applications (CARA).

11 Jun 2024

Study Highlights Key Protein-Lipid Interactions in Mitochondrial Energy Production

By studying mutations in yeast and human cells, Johns Hopkins Medicine scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

10 Jun 2024

Dundee Scientists Reveal Inner Workings of PINK1 Molecular Switch in Parkinson's Disease

Scientists at the University of Dundee have uncovered the inner relay of a molecular switch that protects the brain against the development of Parkinson's disease.

10 Jun 2024

Study Finds Essential Role of Orco Protein in Ant Olfactory Neuron Survival and Social Interaction

While smell plays a considerable role in the social interactions of humans-;for instance, signaling fear or generating closeness-;for ants, it is vitally important.

10 Jun 2024

Peptidomimetics Unlock New Potential in Drug Discovery

Collaborating with the Universities of Bristol and Leeds, researchers at the University of Birmingham have effectively demonstrated a method for modifying peptides to transform them into potentially useful tools for drug discovery and disease diagnosis

10 Jun 2024

Study Unveils Broader Immune Response in EBV-MS Connection

Epstein-Barr virus (EBV) may have a greater effect on the development of multiple sclerosis (MS) than previously believed due to a higher level of cross-reactivity, which occurs when the immune system binds to the incorrect target.

10 Jun 2024

New research identifies and mitigates bias in CRISPR-Cas9 gene editing

A phenomics approach to study proximity bias and the unrelated chromosomal truncations.

10 Jun 2024

Unveiling the Chemical Secrets of Coral Reefs and Insights into Marine Health

What species exist on this coral reef, and how healthy are they?

7 Jun 2024

Columbia Studies Uncover Misidentification of Gut Stem Cells

Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.

7 Jun 2024

Determining Sex in Ants

Researchers at the universities of Mainz and Lausanne have identified a noncoding gene as the deciding factor in determining sex in Argentine ants.

From University of Mainz 7 Jun 2024

Critical NPC Protein Nup358 Linked to Myeloid Disorders

Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence cell survival, proliferation, and differentiation.

6 Jun 2024

Breakthrough Study Identifies Critical Protein for Blood Stem Cell Self-Renewal

UCLA scientists have identified a protein that plays a critical role in regulating human blood stem cell self-renewal by helping them sense and interpret signals from their environment.

6 Jun 2024

Genetic Clues Unveil New Insights into Restless Leg Syndrome

Scientists have discovered genetic clues to the cause of restless leg syndrome, a condition common among older adults.

6 Jun 2024

Study Unveils Key Mechanism of Telomere Maintenance by CST–Polα/Primase

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, resulting in telomere disorders with serious health consequences.

6 Jun 2024

Coordinated Proteins Aid the Immune System in Detecting and Destroying Threats

Bacteria, parasites, and viruses—the immune system tackles them all. Cells known as macrophages are at the forefront of the human immune response, recognizing intruders and controlling how the entire immune system responds.

6 Jun 2024

How Tumor-Associated Fibrosis Shapes Immune Responses

Immunotherapy is based on harnessing a person's own immune system to attack cancer cells. However, patients with certain tumors do not respond to these therapies and it remains unclear why.

5 Jun 2024

Exploring the Dynamic Interactions of Circadian Clock Proteins

Circadian clocks, which drive circadian rhythms, are entwined with many essential systems in living things including plants, fungi, insects, and even humans.

5 Jun 2024

GSE3 Gene Editing Paves the Way for Mechanized Hybrid Rice Breeding

In a study published in Nature Plants, Prof. LI Yunhai from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences and Profs. ZHU Xudong and WANG Yuexing from the China National Rice Research Institute have identified an ideal small grain size gene, GSE3.

5 Jun 2024