Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

New Methods to Modify Molecular Structure Could Lead to More Tailored Drugs

For years, the top desire among those engaged in the development of pharmaceutical drugs was to find a simple method for substituting a carbon atom with a nitrogen atom in a molecule.

2 Nov 2023

Study Identifies Significant Changes in Peptides During Pyroglutamination

Peptides are biomolecules formed when two or more amino acids that perform key functions in the human organism, such as hormones, neurotransmitters, painkillers and antibiotics, bind together. For this reason, they are much studied and used by the pharmaceutical industry, for example.

2 Nov 2023

Scientists Unlock the Structure of Vesicular Monoamine Transporter 2

Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal communication.

2 Nov 2023

Novel Activation Mechanism for First Identified Oncogene

In the late 1970s, the link between the c-Src gene and cancer was unveiled, marking the identification of the inaugural oncogene.

1 Nov 2023

Developing New Strategies for Soybean Molecular Breeding

The soybean (Glycine max) stands as a significant economic crop, offering valuable resources such as edible oil, plant-based protein, and various essential nutrients for human consumption.

31 Oct 2023

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

Enhancing treatment options for triple-negative breast cancer (TNBC), a highly aggressive tumor with a grim prognosis and limited therapeutic possibilities has proven to be a formidable challenge.

31 Oct 2023

New Modular Nanoparticle Technology Opens the Door to a Variety of Therapeutic Approaches

Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins.

31 Oct 2023

Revealing the Protein Secrets of Plant Root Sealing for Sustainable Agriculture

Scientists have uncovered a protein that plays a crucial role in sealing plant roots, thereby controlling the absorption of nutrients and water from the soil.

30 Oct 2023

Unlocking the Mystery of N-Terminal Acetylation’s Impact on Protein Degradation

Scientists at the University of Bergen (UiB) have discovered that proteins employ a shared chemical marker as a protective shield against degradation, thereby influencing their mobility and the aging process.

30 Oct 2023

Genetics can Improve the Diagnostic Value of Cyanobacterial Biomarkers

Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems.

30 Oct 2023

Uncovering New Insights Into Primate Brain Evolution

In a recent research investigation, scientists from Yale University unveiled the molecular pathways responsible for the developmental distinctions that set primates apart from mice.

27 Oct 2023

Role of Chloroplasts’ Dual Function From Photosynthesis to Immune Defense

For a long period, scientists have been aware of chloroplasts' role in converting solar energy into plant food.

26 Oct 2023

Unveiling the Intricacies of Sperm Transformation

Scientists from Stockholm University have revealed the concealed complexities behind the transition of sperm from inert observers to active swimmers.

26 Oct 2023

Revolutionizing Drug Discovery: The Role of AI in Lead Optimization

Lead optimization in the field of drug discovery poses a formidable challenge, predominantly hinging on conjectures and the expertise of medicinal chemists.

25 Oct 2023

Wolbachia’s Fertility Magic: Implications for Mosquito Population Control

A recent investigation uncovers the biological processes through which a particular bacteria strain belonging to the Wolbachia genus may boost the reproductive capabilities of the insects it invades.

25 Oct 2023

Engineering Plants to Turn Red in the Presence of Toxic Pesticide

Imagine if houseplants could alert one to unsafe water conditions. Scientists are making strides toward this innovative idea by successfully modifying a plant to change its color to beet red when it detects the presence of a prohibited and harmful pesticide.

24 Oct 2023