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Novel Bacterial Immune Weapon that Starves Viral Invaders

The discovery of Cat1 reveals how CARF effectors use complex structures to inhibit viral replication, advancing our understanding of bacterial immune responses.

19 May 2025

Molecular Mechanism Revealed by Stop-Motion Electron Microscopy

Using electron microscopy, researchers illustrate FusB's role in antibiotic resistance, providing a molecular-level understanding of fusidic acid interactions.

19 May 2025

Decoding a 3-Billion-Year-Old Cyanobacterial Nanodevice

Scientists unveil the structure of a light-harvesting nanodevice in ancient cyanobacteria, revealing insights into early oxygen-producing photosynthesis.

19 May 2025

Fitness Fight: Native Bees Struggle Against Invasive Honey Bee

New Curtin University research has revealed that high densities of European honey bees could be harming Australian native bees’ ‘fitness’ by reducing their reproductive success and altering key traits linked to survival.

19 May 2025

Understanding Particle Drift and its Influence on Oral Drug Absorption Using Flux Tools

Explore how particle drift influences oral drug absorption and why flux tools are essential for accurate assessment.

From Pion Inc 19 May 2025

SWEET13 Gene Unlocks Sugar Accumulation in Sorghum Grains

Sorghum millet is seen as the crop plant of the future: It builds up a particularly high amount of biomass and thrives in harsh conditions.

17 May 2025

Single Cell Sequencing Uncovers Hidden Drivers of Severe Celiac Disease

Scientists have identified mutated immune cell clones that could point to improved treatment for refractory celiac disease.

17 May 2025

Carriers of Recessive Disorders Face Hidden Health and Reproductive Problems

As a group, carriers of recessive disorders are slightly less healthy and have a reduced chance of having offspring.

16 May 2025

Breakthrough Study Identifies Unique Breast Cancer Genes in South African Women

Genetic factors contribute to some 30% of breast cancer cases in SA, necessitating investment in genomic research in African contexts.

16 May 2025

New 3D Stem Cell Model Mimics Human Amniotic Sac Development

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization.

16 May 2025

Scientists Develop EvoCAST for Efficient and Accurate Gene Insertion

Ask scientists what gene editing tool is most needed to advance gene therapy, and they'd probably describe a system that's now close to realization in the labs of Samuel Sternberg at Columbia University Vagelos College of Physicians and Surgeons and David Liu at the Broad Institute of MIT and Harvard.

16 May 2025

Wuxi Biologics Completes First Commercial PPQ Campaign at 15,000L Production Line in Hangzhou Site

WuXi Biologics ("WuXi Bio"), a leading global Contract Research, Development and Manufacturing Organization (CRDMO), announced the successful completion of the first commercial project Process Performance Qualification (PPQ) campaign for its three sets of 5,000L single-use bioreactors (SUBs) in the second drug substance line of its MFG20 facility at the Hangzhou site.

16 May 2025

Protein Balance Offers Key to Overcoming Immunotherapy Resistance

Immunotherapy uses a person's own immune system to fight cancer. Immune checkpoint inhibitors are one class of immunotherapy that block specific proteins from slowing the immune response.

15 May 2025

Real Time RNA Tracking in Plants Using Fluorescent Biosensors

RNA acts as a messenger inside cells, carrying instructions from DNA that are translated into proteins that are essential for how cells function.

15 May 2025

Loss of SOX9 Gene Linked to Aggressive Colorectal Cancer

Colorectal cancer is the second leading cause of cancer-related death globally. Although some of the molecular changes associated with colorectal cancer are known, how they contribute to cancer development is not yet well defined.

15 May 2025

Variance Analysis Enhances Genetic Risk Prediction for Blood Cell Traits

A Nature Communications study shows that incorporating variance polygenic scores (vPGS) and variance QTLs (vQTLs) improves genetic risk prediction for blood-related diseases, offering new insight into phenotype variability and lifestyle factors like alcohol intake.

15 May 2025

Novel Role for Disordered Protein in Coordinating Key Stages of Gene Expression

Research reveals TAF2's disordered region links transcription and RNA editing, highlighting its role in gene expression regulation and nuclear organization.

15 May 2025

New Mechanism for Selective Host-Microbe Communication in the Gut

The study reveals how APOL9 selectively binds to gut bacteria, enhancing immune responses and maintaining intestinal health through microbial communication.

15 May 2025

Visualizing Intracellular Molecular Landscapes in Single Cells

The t-SPESI method enables real-time visualization of intracellular lipids, offering insights into disease mechanisms and improving diagnostic tool development.

15 May 2025

Sustainable Recycling: Turning Expired Pet Food into Biodiesel and Livestock Feed with Black Soldier Fly Larvae

A new study explores the use of black soldier fly larvae to convert expired pet food into biodiesel and animal feed. This sustainable biorefinery approach offers a low-emission, efficient solution for organic waste management and circular meat production.

14 May 2025