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Discovery of Ball-and-Chain Mechanism Sheds Light on Ion Channel Regulation

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a "ball-and-chain" channel-plugging mechanism, according to investigators at Weill Cornell Medicine.

5 Mar 2025

Neural Mechanism Involved in Leptin Resistance Revealed

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category.

5 Mar 2025

New Approach Could Protect Insulin-Producing Beta Cells from Damage Related to Diabetes

Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity-a harmful condition linked to the progression of type 2 diabetes (T2D).

5 Mar 2025

Pain and Itch Processed by Distinct Neurons in the Anterior Cingulate Cortex

A research team led by KAANG Bong-Kiun, director of the Center for Cognition and Sociality within the Institute for Basic Science (IBS), and KO Hyoung-Gon, professor at Kyung Hee University College of Dentistry, have uncovered the neural mechanisms underlying the processing of pain and itch in the anterior cingulate cortex (ACC).

5 Mar 2025

Arab Pangenome Reference Provides New Path for Advancing Precision Medicine

Creation of a comprehensive genetic representation for more than 2.5 billion people across the Middle East and South Asia could make a major contribution towards advancing precision medicine, a publication in Nature Medicine reveals.

5 Mar 2025

AI-powered Forensic Tool Predicts Traumatic Brain Injuries With 94% Accuracy

A novel AI framework predicts traumatic brain injury severity from police reports, achieving over 94% accuracy by integrating biomechanics and machine learning.

5 Mar 2025

Colossal Creates the Colossal Woolly Mouse, Showcasing Breakthroughs in Multiplex Genome Editing and Trait Engineering on the Path to a Mammoth

In an extraordinary achievement of advanced multiplexed genome engineering, Colossal Biosciences announces the birth of the Colossal Woolly Mouse—mice engineered to express multiple key mammoth-like traits that provide adaptations to life in cold climates.

5 Mar 2025

New Insights Into Ageing Revealed

The way in which blood stem cells evolve over a lifespan differs greatly between humans and mice, new research reveals. The findings provide a new understanding of the critical factors that influence tissue ageing.

5 Mar 2025

Synthetic Microbiome Treatment Prevents C. difficile Infection in Mice

A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans, according to a team of researchers at Penn State.

4 Mar 2025

New CRISPR Method Enhances Surveillance of Antibiotic Resistance in Wastewater

Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections in humans and animals.

4 Mar 2025

New Genetic Clues Could Explain Prostate Cancer’s Aggressive Progression

Scientists from UCLA, the University of Toronto and the University of Melbourne have uncovered new genetic clues that explain why some prostate cancers remain slow-growing while others become life-threatening.

4 Mar 2025

Scientists Unveil Molecular Process of Polymerase Theta in Cancer Cells

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code.

4 Mar 2025

Gut Microbes Transform Excreted Glucose into Crucial Fatty Acids

Gut microbes that were thought to feed exclusively on dietary fiber also get fed sugar from our guts, from which they produce short-chain fatty acids that are crucial to many body functions.

4 Mar 2025

Novel Python Pipeline Enables Genome-Scale Primer Design for Accurate Diagnostics

Zhang Liye Laboratory researchers have created a new tool that will change the way researchers design primers for pathogen detection.

4 Mar 2025

Unlocking the Secrets of Fertilization Inhibition

A research team headed by Yale scientists has elucidated the workings of a natural biological process that blocks the interaction between sperm and egg, thus inhibiting fertilization.

4 Mar 2025

New Tool to Map the Origins and Journeys of Cells in Development and Disease

A new computational tool allows researchers to understand how the diverse cell types of the human body are made during development, and how diseases progress over time at the cellular level.

4 Mar 2025

Limula Unveils LimONE: A Breakthrough in End-to-End Cell Therapy Manufacturing

Limula has unveiled LimONE, a disruptive cell therapy manufacturing solution that automates complex and fragmented processes into a seamless workflow.

From Limula SA 4 Mar 2025

Lactylation Levels Influence Cardiac Development and Regeneration in Mice

This study is led by Dr. Xiaodong Luan (Institute of Clinical Medicine, Peking Union Medical College Hospital), Dr. Shuyang Zhang (Department of Rare Diseases, Peking Union Medical College Hospital) and Dr. He Huang (Shanghai Institute of Materia Medica, Chinese Academy of Sciences).

3 Mar 2025

New AI-Based Device Makes Flow Cytometry Affordable and Accessible

A team of researchers at the George R. Brown School of Engineering and Computing at Rice University has developed an innovative artificial intelligence (AI)-enabled, low-cost device that will make flow cytometry ⎯ a technique used to analyze cells or particles in a fluid using a laser beam ⎯ affordable and accessible.

3 Mar 2025

Study Clarifies Genetic Thresholds for Diagnosing SCA6

The Department of Neurology at Niigata University and National Center of Neurology and Psychiatry has identified pathogenic thresholds for the CAG repeat units (RU) of the CACNA1A gene that causes SCA6.

3 Mar 2025