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Novel Tool moPepGen Uncovers Hidden Genetic Variants at the Protein Level

Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.

17 Jun 2025

Ant Evolution Traced Through Genomic Reshuffling Across 100 Million Years

Aristotle praised the political organization of ant colonies while ancient Chinese Daoists appreciated ants as illustrative symbols showing how ephemeral human ambitions and power are.

17 Jun 2025

Hippocampal Neurons Show Surprising Flexibility in Brain Signal Processing

The brain is constantly mapping the external world like a GPS, even when we don't know about it. This activity comes in the form of tiny electrical signals sents between neurons -- specialized cells that communicate with one another to help us think, move, remember and feel.

17 Jun 2025

Breakthrough Reaction Simplifies Synthesis of Bioactive Polycyclic Molecules

Organic chemistry features a wide array of reactions for creating complex molecules, among which the Diels–Alder reaction stands out for its versatility and precision.

17 Jun 2025

Evosep Joins P4ML to Power World’s Largest Multi-Omic Human Health Study of Two Million Samples

Evosep, a global leader in robust, high-throughput proteomics technologies, has been selected as the proteomics platform provider for the P4ML - OMICAssist Study—the world's largest multi-omic precision medicine initiative, launched by P4ML alongside its strategic academic, health regulatory, and semi-state partners in the United Arab Emirates.

From Evosep 17 Jun 2025

Bacteria Use Harpoon-Like Weapons to Kill and Eat Their Neighbors

Bacteria are microscopic murderers. We've long known that bacteria kill each other, it's part of microbial life.

17 Jun 2025

Study Finds Shared Brain Signature Across Autism Variants

New research from the University of Minnesota Medical School suggests that different genetic forms of autism may lead to similar patterns in brain activity and behavior. The findings were recently published in Nature Neuroscience.

16 Jun 2025

TUM Scientists Develop Breakthrough Method to Monitor CAR-T Cells

In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets.

16 Jun 2025

Shared Brain Activity Patterns in Diverse Genetic Forms of Autism

Research from the University of Minnesota identifies common neural patterns in autism, suggesting genetic variants influence brain activity and behavior.

16 Jun 2025

Llama Antibodies Provide Broad Protection Against Multiple Coronaviruses

Researchers identify small llama-derived antibodies that neutralize multiple coronaviruses, targeting a stable region of the spike protein for broad protection.

16 Jun 2025

Targeting iRhom2 to Control ADAM17-Related Diseases

The atomic structures of ADAM17 and iRhom2, revealed by UC researchers, offer new avenues for developing precise treatments for chronic inflammatory conditions.

16 Jun 2025

Study Shows Fibronectin Tension Loss Correlates With Breast Cancer Progression

Fibronectin fibers lose tension in invasive breast cancer, unlike in healthy or DCIS tissues, suggesting a mechanical marker for tumor progression.

16 Jun 2025

Study Reveals RNA Polymerase I Stalling Mechanism at Abasic DNA Damage Sites

New study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for repair in dividing cells.

16 Jun 2025

Frog Egg Extracts Illuminate the Untangling Mechanism of DNA Knots

Research reveals how G-quadruplex DNA structures are untangled, highlighting a role for RNA in genome stability and potential cancer therapy strategies.

13 Jun 2025

Scientists Uncover Cyanobacteria’s Circadian Clockwork

The study uncovers how KaiC regulates circadian rhythms in cyanobacteria through a unique phosphorylation mechanism, offering insights into biological clocks.

13 Jun 2025

New Genetic Marker Panel Aims to Save Koalas from Extinction

Standardized genetic testing for koalas at UQ is a game-changer for conservation, improving collaboration and understanding of genetic diversity in populations.

13 Jun 2025

Flipped DNA Segments Help Fish Rapidly Evolve into New Species

Researchers have found that chunks of 'flipped' DNA can help fish quickly adapt to new habitats and evolve into new species, acting as evolutionary 'superchargers'.

13 Jun 2025

Integrating Imaging and Molecular Profiling to Transform Treatment of Intrahepatic Cholangiocarcinoma

ICCA accounts for 10–15% of primary liver cancers and is notorious for late-stage diagnosis and resistance to chemotherapy and radiotherapy.

13 Jun 2025

Unlocking Drug Discovery with SOAR's Innovative Resource

Northwestern's SOAR database enhances drug discovery by mapping gene activity, aiding researchers in identifying treatment targets and understanding diseases.

13 Jun 2025

New Technique Revolutionizing Single-Cell Analysis with Lower Costs and Greater Scale

A new single-cell RNA analysis method, STAMP, significantly reduces costs and biases, allowing for comprehensive profiling of diverse cell populations.

13 Jun 2025