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Role of LADs and Epigenetic Pathways in Nuclear Architecture During Early Mouse Embryo Development

A new study in Cell reveals that lamina-associated domains (LADs) in early mouse embryos are shaped by dynamic epigenetic pathways, highlighting how histone modifications and chromatin structure guide nuclear architecture during development.

6 May 2025

Memories of Cold Experiences Influence Metabolism and Thermoregulation

A groundbreaking study reveals that recalling cold experiences can activate thermoregulation and metabolism in mice, suggesting memory-based interventions could help treat obesity, diabetes, and temperature-related disorders like Raynaud’s disease.

6 May 2025

3D Printing Collagen Scaffolds with Perfusable Systems for Tissue Engineering

Scientists have developed high-resolution 3D-printed collagen scaffolds with internal perfusion systems, enabling complex, vascularized tissue models that support cell viability, growth, and insulin secretion

6 May 2025

Shift Work Impairs Muscle Clocks, Potentially Speeding Up Age-Related Decline

Muscle cells possess their circadian clocks, and research indicates that disrupting these clocks through shift work can significantly affect the aging process.

6 May 2025

Gene Deletion in Wheat Reduces Allergenic Gluten

Wheat serves as a significant source of calories, carbohydrates, and protein globally, with its unique gluten proteins providing texture and elasticity to bread and pasta dough.

6 May 2025

Key Regulators of Mutant Huntingtin Protein in Neuronal Transport

Ten years ago, researchers from the University at Buffalo provided some insight into a long-standing neuroscience conundrum: How precisely does Huntington's disease result from a mutation in the huntingtin protein (HTT)?

6 May 2025

Evolutionary Rescue in Microbes Leads to the Collapse of Mutualism

Microorganisms –defined as very small living beings, invisible to the naked eye, comprising bacteria, fungi, viruses or others– naturally compete and cooperate in nature for survival.

5 May 2025

Study Reveals T Cell Plasticity as a Key Driver of Systemic Autoimmunity

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.

5 May 2025

New Gene Editing Tool Alters Mitochondrial Mutation Levels in Stem Cells

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes.

5 May 2025

New Neural Circuit Discovery Explains Precision Steering in Fruit Flies

When a fruit fly is navigating straight forward at high speed, why does it know that it's not straying off course? Because as long as the fly moves directly forward, the visual scene shifts from front to back in a near-perfect mirror image across both retinas – generating, in other words, a symmetrical visual motion pattern.

2 May 2025

Lipid Peroxidation in Lysosomes Unleashes Ferroptosis in Tumors

The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death.

2 May 2025

Tracheal Basal Cells Identified as Origin of Lung Squamous Cell Carcinoma

The 'cell of origin' of the second most common lung cancer and the way that it becomes dominant in the lung have been discovered, in a new study in mice and humans from researchers at UCL, the Wellcome Sanger Institute and the University of Cambridge.

2 May 2025

INTEGRA Biosciences’ Tools Support Vital PCR Purification Protocols

INTEGRA Biosciences offers a variety of solutions to streamline crucial PCR purification workflows with magnetic beads and spin columns.

2 May 2025

Vapourtec Video Showcases Fully Automated Peptide Synthesis

A recent video produced by Vapourtec highlights the patented automatic Variable Bed Flow Reactor (VBFR) demonstrating fully automated solid phase peptide synthesis.

2 May 2025

Dr. Jeremy Poschmann’s data-driven approach to immune profiling and translational science

Dr. Jeremy Poschmann discusses data-driven approaches in genomics, revealing how immune profiling can predict disease risk and improve patient outcomes.

1 May 2025

Enhanced Stem Cell Sorting Method Boosts Cultured Meat Potential

By optimizing cell surface marker combinations, the study significantly improves stem cell purity and myogenic potential during passaging, offering a robust source of seed cells essential for advancing cultured meat technologies.

30 Apr 2025

Single DNA Mutation Dysregulates Key Tumor-Suppressing Pathways in Blood Cancer

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumor-suppressing pathways, opening up new avenues for blood cancer treatment.

30 Apr 2025

New Mass-Spectrometry Technique Boosts Enzyme Screening Speed by Up to 1000 Times

Scientists have developed a new technique to screen engineered enzyme reactions, which could lead to faster and more efficient creation of medicines and sustainable chemicals.

30 Apr 2025

New Software Tool Helps Scientists Identify Aging Cells in Tissues

For human health, prematurely aging cells are a big problem. When a cell ages and stops growing, its function changes, which can cause or worsen cardiovascular disease, Alzheimer’s disease and other chronic diseases.

29 Apr 2025

Genetic Diversity in Wild Rice Offers Clues for Crop Improvement

A new study, seen in Nature Genetics and led by researchers at King Abdullah University of Science and Technology (KAUST; Saudi Arabia) and Wageningen University & Research (the Netherlands), provides new insights on rice evolution, showing how the DNA of this valuable crop has changed across species.

29 Apr 2025