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Cells Harvested From Urine May Have Diagnostic Potential for Kidney Disease

Genes expressed in human cells harvested from urine are remarkably similar to those of the kidney itself, suggesting they could be an important non-invasive source of information on the kidney.

20 Mar 2024

Using Genomic Methods to Track Pesticide Resistance

Pesticides are used by farmers to manage agricultural pests. However, pesticide-resistant insects frequently become immune to their toxins.

19 Mar 2024

The Assemblage of Nuclear Sub-Structures

Researchers from the lab of Rohit Pappu and associates at the Center for Biomolecular Condensates have figured out how nucleolar sub-structures are assembled, a first for the condensate field.

19 Mar 2024

New Research Sheds Light on the Evolution of Skin Appendages

The evolution of hair had a crucial role in the development of animals, including humans. However, it was previously unknown where the genetic code for hair originated in the evolutionary process.

19 Mar 2024

Study Reveals Neural Basis of Odor Perception

Scents, such as coffee, flowers, or freshly baked pumpkin pie, are created by odor molecules released by various substances and detected by our noses.

19 Mar 2024

Soil Bacteria Gene Discovery Offers Hope for Bioremediation Efforts

Some soil bacteria can acquire sets of genes that enable them to pump the heavy metal nickel out of their systems, a study has found.

19 Mar 2024

New Biomarker Offers Early Detection of ALS and FTD

Two progressively degenerative diseases, amyotrophic lateral sclerosis (ALS, commonly known as Lou Gehrig's disease) and frontotemporal dementia (FTD, recently in the news with the diagnoses of actor Bruce Willis and talk show host Wendy Williams), are linked by more than the fact that they both damage nerve cells critical to normal functioning -; the former affecting nerves in the brain and spinal cord leading to loss of movement, the latter eroding the brain regions controlling personality, behavior and language.

19 Mar 2024

Tree Frogs Choose Warmth Over Height for Eggs

There are some peculiar habits that tree frogs have when it comes to laying eggs. They frequently deposit their eggs on the ground rather than the tree branches where they typically reside.

18 Mar 2024

Targeting T Cell Metabolism to Boost Cancer Therapies

Recent findings from the lab of Jessica Thaxton, PhD, MsCR, in the UNC School of Medicine's Department of Cell Biology and Physiology, as well as associates in the Lineberger Comprehensive Cancer Center's Immunotherapy Group, have provided new insights into T-cell metabolism that may improve immunotherapies that depend on T cells to combat cancer.

18 Mar 2024

Baby Gut Bacteria Found to Play Crucial Role in Immune Development

Researchers at Weill Cornell Medicine have shown that certain bacteria invade the stomach soon after birth and produce serotonin, a neurotransmitter that helps teach gut immune cells.

18 Mar 2024

Protein Fragments Uncover New Extremophiles, Aiding Alien Life Search

Microorganisms with perfect adaptations can survive in harsh settings, such as deep-sea tunnels and mountain peaks.

18 Mar 2024

Students Work with Experts to Create a High-Quality Pear Genome Assembly

Pears are big business in the Pacific Northwest US. But did you know that traditional pear breeding has remained largely unchanged for centuries?

18 Mar 2024

Machine Learning Accelerates Personalized T Cell Therapy Development for Cancer Patients

Making a personalized T cell therapy for cancer patients currently takes at least six months; scientists at the German Cancer Research Center and the University Medical Center Mannheim have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.

18 Mar 2024

SIRPβ1 Gene Mutation Alters Alzheimer's Disease Progression

The scientist of the Faculty of Medicine of the University of Malaga José Luis Royo has coordinated a study that summarizes eight years of research and brings together 100 multidisciplinary specialists, identifying a mutation that alters Alzheimer's disease progression.

18 Mar 2024

Adhesion GPCR Mayo Plays Key Role in Midgut Development of Fruit Flies

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more.

18 Mar 2024

Research Uncovers Individuality in Roundworm Neural Circuits

Joint research led by Yu Toyoshima and Yuichi Iino of the University of Tokyo has demonstrated individual differences in and successfully extracted commonalities from the whole-brain activity of roundworms.

18 Mar 2024

Metabolic Insights into Immune Cell Activation and Response

Researchers from Children's Hospital of Philadelphia identified a key metabolite in cells that helps direct immune responses and explains at a single cell level why immune cells that most efficiently recognize pathogens, vaccines, or diseased cells grow and divide faster than other cells.

18 Mar 2024

Transcriptome Profiling Reveals Age-Associated Changes in the Human Brain

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 5, entitled, "Genome-wide transcriptome profiling and development of age prediction models in the human brain."

18 Mar 2024

Exploring the Link Between Gut Health and Effective Milk Allergy Treatment

Exploring the Link Between Gut Health and Effective Milk Allergy Treatment At the RIKEN Center for Integrative Medical Sciences in Japan, researchers under the direction of Hiroshi Ohno have found a connection between gut microbiota and the effectiveness of oral immunotherapy for milk allergies.

15 Mar 2024

Scientists Identify Mechanism Behind Post-Traumatic Fear Responses

Neurobiologists have discovered how stress causes the brain to become fearful in situations like Post-Traumatic Stress Disorder (PTSD) and how to stop it.

15 Mar 2024