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Researchers demonstrate a possible new way of generating insulin-producing cells

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis.

14 Jun 2022

Computational approach could enable large-scale analyses of tumor-specific total mRNA levels from patient samples

Researchers at The University of Texas MD Anderson Cancer Center have developed a new approach to quantify tumor-specific total mRNA levels from patient tumor samples, which contain both cancer and non-cancer cells.

14 Jun 2022

Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

Orbit Discovery Ltd., (“Orbit”) a privately held biopharmaceutical company focused on discovering candidate peptide therapeutics harnessing proprietary affinity and cell-based functional screening platforms, has been awarded a Smart grant by Innovate UK, the UK’s innovation agency.

From Orbit Discovery 14 Jun 2022

OTUD3 shows opposing effects in innate immunity to RNA and DNA viruses

The identification of pathogen-associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs) is the first step in initiating an immune response to viral infection.

13 Jun 2022

Study shows how probiotic bacteria may lower the risk of ER+ breast cancer

A new study presented at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga., suggests that probiotic bacteria may improve the anti-cancer actions of the breast cancer drug tamoxifen as well as other endocrine-targeted therapies, potentially lowering the risk of estrogen receptive positive (ER+) breast cancer.

13 Jun 2022

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

To drive anabolic processes, epithelial ovarian cancer (EOC) is heavily reliant on the tricarboxylic acid (TCA) cycle and oxidative phosphorylation.

13 Jun 2022

Researchers analyze ancient DNA cultural imprint in the pacific region

An “explosion” of intermixing cultures and genetics in Wallacea, an island region north of Australia, has been revealed through DNA analysis of ancient human remains, leaving an imprint that can still be seen in East Indonesians today.

13 Jun 2022

A signaling molecule can make plants more resistant to flooding, research shows

Extreme weather phenomena are on the rise worldwide, including frequent droughts and fires. Floods are also a clear consequence of climate change.

13 Jun 2022

Ningaloo corals are not well-equipped to survive a warming ocean, study finds

The relatively pristine coral populations of WA's inshore Kimberley region are better equipped to survive ocean warming than the World Heritage-listed Ningaloo Marine Park, according to a new Curtin University study.

13 Jun 2022

Nanomaterials may be the key to better monitoring and treatment of cardiovascular diseases

Cardiovascular diseases are the leading cause of death across the globe, responsible for about 17.9 million (32%) of all deaths worldwide every year.

13 Jun 2022

New form of rapid test can detect infections in farm animals

Researchers at McMaster University have developed a new form of rapid test to detect infections in farm animals, responding to the rising threat of dangerous outbreaks.

13 Jun 2022

Researchers utilize AI to reveal hitherto unknown 3D structures in rotavirus spike protein

The three types of rotavirus that cause gastroenteritis in individuals, known as groups A, B, and C, are the most well-known and afflict predominantly youngsters.

10 Jun 2022

Researchers discover a new interferon-gamma receptor signaling pathway

The interferon-gamma receptor (IFNgR) signaling pathway has been identified to be crucial for the vulnerability of glioblastoma tumors to death by CAR T-cell immunotherapy, according to researchers at Massachusetts General Hospital (MGH).

10 Jun 2022

Researchers analyze and demonstrate how organelles divide into cells

The research, headed by Professor Michael Schrader of the University of Exeter, looked at peroxisome dynamics and discovered new ways for them to divide.

From University of Exeter 10 Jun 2022

Origin of chromatin in ancient microbes happened 1–2 billion years ago, study reveals

Nature’s storage solution originally emerged in ancient microbes living on Earth around one and two billion years ago, according to researchers at the Center for Genomic Regulation (CRG).

10 Jun 2022

Microorganisms mediate Sphagnum peatmoss resilience to warming

Microorganisms may provide hope that peatlands can withstand hotter temperatures in a changing climate.

10 Jun 2022

Scientists develop tiny probe for minimally invasive interfacing with neural circuits

Researchers at the University of California San Diego and the Salk Institute for Biological Studies have developed a tiny neural probe that can be implanted for longer time periods to record and stimulate neural activity, while minimizing injury to the surrounding tissue.

From UC San Diego 10 Jun 2022

Life Science News

Researchers demonstrate a possible new way of generating insulin-producing cells

Computational approach could enable large-scale analyses of tumor-specific total mRNA levels from patient samples

Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

OTUD3 shows opposing effects in innate immunity to RNA and DNA viruses

Study shows how probiotic bacteria may lower the risk of ER+ breast cancer

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

Researchers analyze ancient DNA cultural imprint in the pacific region

A signaling molecule can make plants more resistant to flooding, research shows

Ningaloo corals are not well-equipped to survive a warming ocean, study finds

Nanomaterials may be the key to better monitoring and treatment of cardiovascular diseases

New form of rapid test can detect infections in farm animals

Researchers utilize AI to reveal hitherto unknown 3D structures in rotavirus spike protein

Researchers discover a new interferon-gamma receptor signaling pathway

Researchers analyze and demonstrate how organelles divide into cells

Origin of chromatin in ancient microbes happened 1–2 billion years ago, study reveals

Microorganisms mediate Sphagnum peatmoss resilience to warming

Scientists develop tiny probe for minimally invasive interfacing with neural circuits

New chemical-only process may represent an important breakthrough in creating customized mRNA vaccines

Scientists discover that most synonymous mutations are strongly harmful

Gene expression analysis helps identify genes that cause endocrine resistance in breast cancer

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