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Gene therapy may be a safe and effective single-dose treatment for hypophosphatasia

A preclinical study led by scientists at Sanford Burnham Prebys has established that AAV8-TNAP-D10--a gene therapy that replaces a key enzyme found in bone--may be a safe and effective single-dose treatment for hypophosphatasia (HPP).

8 Jun 2021

Consuming large amounts of daily caffeine may increase the risk of glaucoma

Consuming large amounts of daily caffeine may increase the risk of glaucoma more than three-fold for those with a genetic predisposition to higher eye pressure according to an international, multi-center study.

8 Jun 2021

NIH grant awarded to model and analyze protein-ligand interactions in cancer research

Computer scientist Lydia Kavraki of Rice University's Brown School of Engineering has won a prestigious National Institutes of Health U01 grant to develop a new approach to model and analyze protein-ligand interactions in cancer research.

8 Jun 2021

Study reveals how coronavirus aerosols flow through the lower lungs

When we inhale isolated coronavirus particles, more than 65% reach the deepest region of our lungs where damage to cells can lead to low blood oxygen levels, new research has discovered, and more of these aerosols reach the right lung than the left.

8 Jun 2021

Single biomarker in the blood can accurately indicate underlying neurodegeneration

Levels of a protein called neurofilament light chain (NfL) in the blood can identify those who might have neurodegenerative diseases such as Down's syndrome dementia, motor neuron disease (ALS) and frontotemporal dementia, when clinical symptoms are not definitive.

8 Jun 2021

Study shows how immune cells organize themselves in the epidermis

The human skin is essentially an organ, a fact that that is easy to forget. It is also the largest organ and is continuously exposed, charged with keeping the human inner biology safe from the threats of the outside world.

8 Jun 2021

Harmful DNA mutations play a key role in the conservation of threatened species

Researchers in Lund, Copenhagen, and Norwich have demonstrated that detrimental mutations in DNA play a vital—but often overlooked—role in vulnerable species translocation and conservation initiatives.

8 Jun 2021

New species of marine scale worm give evidence of male dwarfism

An evolutionary riddle awaited in the Kumano Sea, off the southeast coast of Japan. Hermit crabs abandoned shells and mollusks were among the materials retrieved from the muddy sea floor by the researchers.

8 Jun 2021

Food scientists aim to create healthier and tastier plant-based proteins

As meat consumption grows throughout the world, food scientists are working to develop better-tasting, more sustainable, and healthier plant-based protein products that replicate cheese, fish, eggs, milk, and meat.

8 Jun 2021

Nutritional supplement can help bolster key functions for people with brain disorders

An international subject pool was studied to confirm the effectiveness of a whole food complete vitamin and meal replacement product, IQed. The article, co-authored by Lisa Geng; Francine Hamel, EdD, SLP-CCC; Doreen Lewis, Ph.D., appeared in the peer-reviewed journal, Alternative Therapies (Altern Ther Health Med 2021 Mar;27(2):11-20).

7 Jun 2021

Study explores how the microbiome could be manipulated for good

There's a lot of interest right now in how different microbiomes--like the one made up of all the bacteria in our guts--could be harnessed to boost human health and cure disease. But Daniel Segrè has set his sights on a much more ambitious vision for how the microbiome could be manipulated for good: "To help sustain our planet, not just our own health."

7 Jun 2021

New insights on how synovial sarcoma develops and spreads

A new study published today in Cancer Discovery, a journal of the American Association for Cancer Research, reports findings that may change the understanding of how synovial sarcoma develops and spreads.

7 Jun 2021

Women need more support to participate in contract farming, study suggests

A new study looking at the benefits of good farmer seed production suggests women need more support to participate in contract farming - to the same extent as their male counterparts - and have more equality along the whole food value chain.

4 Jun 2021

Scientists discover two drugs that provide effective SARS-CoV-2 suppression

COVID-19 continues to claim lives across the world and is infecting millions more. Although several vaccines have recently become available, making significant strides towards preventing COVID-19, what about the treatment of those who already have the infection?

From Tokyo University of Science 4 Jun 2021

Immunotherapy following kidney cancer surgery prolonged disease-free survival rates

Treatment with an immunotherapy drug following kidney cancer surgery, prolonged disease-free survival rates in patients at high risk for recurrence, according to an interim report of a phase 3 clinical trial of adjuvant immunotherapy in this patient population.

4 Jun 2021

Immune therapy after surgery reduces recurrence risk in patients with high-risk melanoma

Patients with high-risk melanoma who had a course of pembrolizumab after their surgery had a longer time before their disease recurred than patients who got either ipilimumab or high-dose interferon after surgery. These findings of a large SWOG Cancer Research Network clinical trial, S1404, will be presented at the ASCO annual meeting June 6, 2021.

4 Jun 2021

Sedimentary sequence provides a continuous record of five million years of climate change

Paleo researcher Charlotte Prud'homme, who until recently worked at the Max Planck Institute for Chemistry and is now a researcher at the Université Lausanne, explains: "The 80-meter-thick sedimentary sequence we found at Charyn Canyon in southeast Kazakhstan provides us with a virtually continuous record of five million years of climate change.

4 Jun 2021

Antibody treatment reactivates the immune defense in advanced-stage cancer patients

Researchers at the University of Turku, Finland, showed that the antibody treatment reactivates the immune defense in patients with advanced-stage cancer. The treatment alters the function of the body's phagocytes and facilitates extensive activation of the immune system.

4 Jun 2021

Some Type 2 diabetes patients could benefit from bone marrow stem cell transplants, study shows

Type 2 diabetes patients who are not overweight and who have had the disorder for less than a decade can benefit from stromal stem cells transplanted from their own bone marrow, according to a study published today in STEM CELLS Translational Medicine.

4 Jun 2021

Study offers an ultra-detailed look into the organization of a living human cell

Sinai Health researchers published a study that offers an ultra-detailed look into the arrangement of a living human cell.

4 Jun 2021

Life Science News

Gene therapy may be a safe and effective single-dose treatment for hypophosphatasia

Consuming large amounts of daily caffeine may increase the risk of glaucoma

NIH grant awarded to model and analyze protein-ligand interactions in cancer research

Study reveals how coronavirus aerosols flow through the lower lungs

Single biomarker in the blood can accurately indicate underlying neurodegeneration

Study shows how immune cells organize themselves in the epidermis

Harmful DNA mutations play a key role in the conservation of threatened species

New species of marine scale worm give evidence of male dwarfism

Food scientists aim to create healthier and tastier plant-based proteins

Nutritional supplement can help bolster key functions for people with brain disorders

Study explores how the microbiome could be manipulated for good

New insights on how synovial sarcoma develops and spreads

Women need more support to participate in contract farming, study suggests

Scientists discover two drugs that provide effective SARS-CoV-2 suppression

Immunotherapy following kidney cancer surgery prolonged disease-free survival rates

Immune therapy after surgery reduces recurrence risk in patients with high-risk melanoma

Sedimentary sequence provides a continuous record of five million years of climate change

Antibody treatment reactivates the immune defense in advanced-stage cancer patients

Some Type 2 diabetes patients could benefit from bone marrow stem cell transplants, study shows

Study offers an ultra-detailed look into the organization of a living human cell

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