Cyagen

Cyagen is a 400-employee company headquartered in Santa Clara, California, with additional locations in Japan and China, and production facilities in China. Cyagen is the world's largest provider of custom-engineered mouse and rat models. Cyagen's services have become well known for its top quality, full guarantee, and competitive prices. Additionally, Cyagen offers a comprehensive series of stem cell products for research use, including cell lines, media, and differentiation kits.

Core competencies:

1. Generation of custom genetically modified rodent models. As a leader in custom rodent models, Cyagen offers a "one-stop-shop" tailored to your gene research needs. Our services range from DNA vector construction to embryonic stem cell manipulation, microinjection, and breeding. All projects are fully customizable and flexible. Customers may outsource any stage of a rodent model project to us. Cyagen has also developed and validated animal models using engineered nuclease technology, which allows for the generation of knockout models at reduced cost and turnaround when compared to traditional ES cell-based gene targeting. This investment has led to significant time and cost savings for our clients.
2. Ready-to-use knockout (KO) catalog models. Cyagen Knockout Catalog Models features over 10,000 knockout mouse models on 100% pure C57BL/6 backgrounds, delivered in as fast as 3 months. These established lines have validated genotyping data, circumventing risks associated with the model generation process. Cyagen’s innovative mouse sperm cryorecovery technology builds on our accumulated experience in custom animal model generation, providing live mice with unmatched reliability, efficiency, and economy. Look-up your gene(s) of interest today – search by gene name or NCBI gene ID.
3. Generation of tailor-made DNA vectors and research-use viruses. Cyagen can construct almost any type of DNA vector to meet your research needs. In 2013, we expanded our service portfolio by launching BAC recombineering and virus packaging services. Cyagen packages virus in two dedicated, independent Class 10,000 ultra-clean virus packaging rooms equipped with Biosafety Level 2 (BSL-2) cabinets and incubators.
4. Production of research-use stem cells and related culture reagents. Cyagen boasts a comprehensive portfolio of research-use stem cell lines, including embryonic stem cells and multiple lineages of somatic stem cells derived from various species. We also provide a variety of supplementing culture and differentiation media to support the growth and maintenance of these cells. All of our products have been widely cited in high-impact journals, including Nature and PNAS.

Cyagen offers an industry-best, 100% money-back guarantee, free consultation and quotations, top tier customer support, and price matching for all major competitors. To date, Cyagen has generated many thousands of custom knockout, knockin and transgenic rodent lines while working with over 500 universities and companies worldwide. Please click here to view a map of our customer base.