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New Database Provides Insights into snoRNA Expression in Zebrafish

Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules whose role in gene regulation and their association with certain diseases, such as inflammatory bowel disease (IBD) or colorectal cancer, has only recently become known.

20 Mar 2025

RNA-Based Active Agents Successfully Shield Plants from Cucumber Mosaic Virus

New RNA-based active agents reliably protect plants against the Cucumber mosaic virus (CMV), the most common virus in agriculture and horticulture. They were developed by researchers at the Martin Luther University Halle-Wittenberg (MLU).

20 Mar 2025

Pregnancy Triggers Small Intestine Growth in Mice

Researchers at the Francis Crick Institute have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a second.

20 Mar 2025

New Insights into How B Cells Strategically Clone High-Affinity Antibodies

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies.

20 Mar 2025

Bioengineering a Luminous Biosensor for Aberrant DNA Detection

Cells contain a DNA sensor called cGAS, which alerts the immune system to viral and bacterial infections, cell death, and cancer-related transformations.

20 Mar 2025

Advanced Imaging Deciphers B Cell Dynamics in Lymph Nodes

Germinal centers are machines of rapid evolution. Germinal centers are tiny clusters in the lymph nodes that refine antibodies through proliferation and mutation to create high-affinity B cells that are suited to control various infections.

20 Mar 2025

Visualizing the Fundamental Process of DNA Strand Separation

The exact moment DNA starts to unravel has been seen by scientists for the first time, exposing a chemical process that is essential for DNA to be the molecule that codes for all life.

20 Mar 2025

New Chromosome Identification System Revolutionizes Alfalfa Research

In a recent study, scientists have developed a revolutionary chromosome identification system for alfalfa, one of the world's most economically vital forage crops.

19 Mar 2025

Researchers Develop RNA "Barcoding" Tool to Track Genetic Exchange in Bacteria

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems.

19 Mar 2025

Rethinking Cancer: Moving Beyond Genetic Mutations to a Holistic View

It's time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from the Institute for Systems Biology, USA, and colleagues in a new essay published March 18th in the open-access journal PLOS Biology.

19 Mar 2025

Genetic Research Uncovers a Lost Chapter of Human Evolution

Utilizing sophisticated analyses grounded in complete genome sequences, researchers at the University of Cambridge have uncovered indications that modern humans emerged from a genetic mixing event involving two ancient populations that diverged approximately 1.5 million years ago.

19 Mar 2025

AI Revolutionizes Cell Analysis for Personalized Cancer Treatment

A groundbreaking artificial intelligence (AI)-driven neural network has been developed to swiftly analyze and interpret millions of cells from patient samples, enabling predictions of molecular alterations within tissues.

19 Mar 2025

Chilean Researchers Rediscover a Frog Lost to Science for 130 Years

The rediscovery of Alsodes vittatus in Chile highlights its conservation status and evolutionary history, emphasizing the need for biodiversity research.

19 Mar 2025

Phytogene Offers a Greener, Cheaper Alternative for Producing Pharmaceuticals

To tackle the inequity in medication access, a societal issue especially in developing nations, a team of undergraduate student-researchers at the University of Ottawa has developed a new biomanufacturing platform called Phytogene.

18 Mar 2025

Brain Research Offers Fresh Insights into the Nature Versus Nurture Debate

Riddle me this: how can it be that reading these words activates nearly identical word-sensitive patches of the brain's visual system in you and nearly every other reader of this story? And that a different set of face-sensitive visual regions-again in almost identical positions in each reader's brain-would activate to process the faces of the researchers, should you meet them?

18 Mar 2025

Scientists Unlock Genetic Secrets of Wild Barley to Improve Crop Yields

An international team of scientists from Australia and China has unveiled the first chromosome-scale genome of a wild barley species, with their findings offering direct implications for more sustainable agriculture and significant yield improvements for Australian grain production.

17 Mar 2025

New Discovery in RNA Splicing Could Transform Treatment of Aggressive Cancers

Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different versions of a film.

17 Mar 2025

Ultrasensitive Pathogen Detection Without Nucleic Acid Amplification

Rashid Bashir, a Bioengineering Professor and Dean of the Grainger College of Engineering oversaw a group of researchers in a project that produced new technology that provides quick, extremely sensitive detection of bacteria and other pathogens at low concentrations that are resistant to multiple drugs.

17 Mar 2025

Extrachromosomal DNA Discovered as a Hidden Factor in Pancreatic Cancer Survival

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%.

14 Mar 2025

Landscape Transcriptomics Sheds Light on Bee Stress and Decline

A new method of examining gene expression patterns called landscape transcriptomics may help pinpoint what causes bumble bees stress and could eventually give insight into why bee populations are declining overall, according to a study led by researchers at Penn State.

14 Mar 2025