Proliferation News and Research

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Identifying the structure of the SEA complex

The mTOR protein is important for cell growth, proliferation, and survival. Its activity fluctuates according to nutrient availability and growth factors like hormones.

1 Nov 2022

The ability of cells to adjust their growth to changing environmental conditions

Growth is a fundamental element of all life on this planet, whether it be a mammal, a single-celled organism, a plankton, or a sequoia.

18 Oct 2022

Bacterial warfare in the gut can have collateral beneficial effects

Nearly ten years ago, a graduate student at UO Jennifer Hampton Hill stumbled upon something fortunate: a peptide produced by gut bacteria that prompted the division of cells that make insulin.

17 Oct 2022

Microbiome manipulation to prevent and cure diseases

Tagbo Niepa, assistant professor of chemical engineering at the University of Pittsburgh, is inspired by this possibility in his research. His work on using the microbiome to enhance human health was recognized with a $2 million New Innovator Award from the National Institutes of Health, which funds “exceptionally creative scientists proposing high-risk, high-impact research.”

From University of Pittsburgh 5 Oct 2022

Researchers reveal key developmental difference between the brains of modern humans and Neanderthals

AZoLifesciences speaks to Dr. Anneline Pinson and Prof. Dr. Wieland B. Huttner from The Max Planck Institute of Molecular Cell Biology and Genetics about their latest research which found a greater neuron production in the frontal lobe during brain development in modern humans than Neanderthals, due to the change of a single amino acid in the protein TKTL1.

From The Max Planck Institute 20 Sep 2022

Antibiotics deplete intestinal flora and weaken the immune response

According to a recent study conducted by scientists at Emory University in Atlanta, the administration of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive type of skin cancer, expedited their metastatic bone growth.

12 Sep 2022

Researchers create a gas that helps to develop and trigger plant immunity

The flash of lightning and the movement of the aurora contain the plasma, the fourth state of matter that scientists have exploited to create a gas that may trigger plant immunity against widespread illnesses.

23 Aug 2022

Biotrophic fungus uses host auxin signaling pathway for its own purposes

Ustilago maydis attacks and reproduces in the aerial parts of the corn plant. At the location of the infection, massive tumor-like tissue growths frequently develop. The size of these galls can exceed that of a child’s skull.

12 Aug 2022

Circadian clocks involve primarily in fat cell growth

According to two studies conducted by researchers at Weill Cornell Medicine, the circadian clocks that keep the body and its cells synchronized to the 24-hour day-night cycle are severely disrupted.

9 Aug 2022

HIV latent cells produce a possible cure investigation

Researchers from the National Institute of Allergy and Infectious Diseases (NIAID) Vaccine Research Center (VRC) and their collaborators gave a presentation recently at AIDS 2022, the 24th International AIDS Conference in Montreal.

1 Aug 2022

Researchers identify the molecular route that leads to autoimmune disease inflammation

Mitochondria are self-contained organelles that reside inside cells and are tasked with producing the chemical energy required to power vital tasks necessary for life and wellbeing. They have their own mini-chromosome and DNA.

From UC San Diego 14 Jul 2022

Scientists link the function of specific domain of proteins to a cancer trigger in humans

Researchers at the Department of Energy's Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins important in plant-microbe biology to a cancer trigger in humans, knowledge that had eluded scientists for decades.

6 Jul 2022

Protecting foods with antimicrobial, plant-based food wrap

Aiming to produce environmentally friendly alternatives to plastic food wrap and containers, a Rutgers scientist has developed a biodegradable, plant-based coating that can be sprayed on foods, guarding against pathogenic and spoilage microorganisms and transportation damage.

From Rutgers University 21 Jun 2022

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

To drive anabolic processes, epithelial ovarian cancer (EOC) is heavily reliant on the tricarboxylic acid (TCA) cycle and oxidative phosphorylation.

13 Jun 2022

Researchers analyze and demonstrate how organelles divide into cells

The research, headed by Professor Michael Schrader of the University of Exeter, looked at peroxisome dynamics and discovered new ways for them to divide.

From University of Exeter 10 Jun 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Scientists demonstrate how stomach stem cells switch from one state to the other upon injury

A stomach adult stem cell population can fulfill two distinct functions: either help with digestion under normal conditions or take the lead on injury response. S

26 May 2022

Gene expression signatures in lymph node cells play an active role in lymphoma development

Researchers from the University of Tsukuba identify gene expression signatures in different types of lymph nodes cells that play an active role in the development of lymphomas.

3 May 2022

Study explains how liver regeneration may help treat liver disease in mice

Other vertebrates, such as fish and lizards, can regenerate organs more effectively than mammals. Salk researchers have discovered a mechanism to partially restore the young condition of liver cells, allowing them to repair damaged tissue at a quicker rate than previously thought.

29 Apr 2022

New 3D in vitro model reveals the origins of human spine

The spinal column is the central supporting structure of the skeleton in all vertebrates. Not only does it provide a place for muscles to attach, it also protects the spinal cord and nerve roots. Defects in its development are known to cause rare hereditary diseases.

28 Apr 2022