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Study shows how mutational signatures are shaped by DNA repair pathways

A research team has examined more than 2700 genomes from C. elegans worms to gain a better understanding on the causes responsible for mutations.

4 May 2020

DNA Damage And Faulty Repair Jointly Cause Mutations

Researchers at EMBL-EBI analyzed over 2700 genomes from C. elegans worms in order to better understand the causes of mutations.

4 May 2020

Choosing alternate pathways of DNA repair to limit harmful chromosomal rearrangements

Homologous recombination is an essential process of DNA repair to maintain genomic integrity of the organism.

From Osaka University 30 Apr 2020

Study traces molecular connections between genetics, gut microbiome and memory

A new study is among the first to trace the molecular connections between genetics, the gut microbiome and memory in a mouse model bred to resemble the diversity of the human population.

29 Apr 2020

Genome analyses explain the reemergence of bluetongue virus in Europe

Bluetongue virus (BTV) is a livestock disease that can lead to devastating health and economic outcomes, but despite this fact, it can be challenging to establish its origin.

29 Apr 2020

Study identifies causative factors for neurodegenerative diseases

Researchers from the HudsonAlpha Institute for Biotechnology, UCSF, and UAB have discovered a new risk factor for various neurodegenerative diseases.

29 Apr 2020

Study shows how DNA mimic protein helps phages to attack their victims

A research team from the Severinov Laboratory at Skoltech, together with their collaborators from Israel and Switzerland, has analyzed a bacterial BREX defense mechanism that was poorly studied to date.

29 Apr 2020

Scientists Double Understanding Of Genetic Risk Of Melanoma

A global collaboration of scientists has more than doubled the known number of regions on the human genome that influence the risk of developing melanoma.

28 Apr 2020

Syphilis bacterium likely uses a single gene to escape the immune system

The bacterium that causes syphilis, Treponema pallidum, likely uses a single gene to escape the immune system, research from UW Medicine in Seattle suggests.

27 Apr 2020

Study develops a memory-intensive approach to visualize genomes

At Ulm University in Germany, a new method has been devised for developing pan-genome subgraphs at various granularities without the need to wait several hours or days for the software to process the complete genome.

27 Apr 2020

Scientists discover how tissues protect their DNA from mechanical stress

In everyday life, our tissues, for example skin and muscle, are stretched, pulled and compressed without causing damage to the cells or the DNA.

24 Apr 2020

DNA may not be the 'blueprint' for life, just a scrambled list of ingredients

The common view of heredity is that all information passed down from one generation to the next is stored in an organism's DNA. But Antony Jose, associate professor of cell biology and molecular genetics at the University of Maryland, disagrees.

23 Apr 2020

Researchers develop new molecular workflow to study single-cell genomics of diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

23 Apr 2020

Study reveals the mechanism used by tuberculosis bacteria for their growth

The structure of a protein that plays a role in importing vitamin B12 into the cells of a tuberculosis (TB)-causing bacterium has been revealed by scientists from the Netherlands, Russia, the United States, and Sweden.

23 Apr 2020

Reference genes could lead to genetic improvement in wheat

Wheat sustains the world. The FAO has stated that wheat is one of the main crops in the world, both in terms of scope and production, and it is also one of the rich sources of vegetable protein and carbohydrates in the human diet.

23 Apr 2020

Identifying Salmonella

AZoLifeSciences speaks to Dr. Silin Tang about her research into the importance of identifying salmonella in food.

23 Apr 2020

Scientists find gene signature linked to worst prognosis in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

Researchers analyze genomic diversifications of five cotton lineages

Come harvest time, the cotton fields look like popcorn is literally growing on plants, with fluffy white bolls bursting out of the green pods in every direction.

21 Apr 2020

A ‘virtual embryo’ for unprecedented single-cell studies

Researchers from EMBL Heidelberg and from the University of Padua School of Medicine have created the first complete description of early embryo development, accounting for every single cell in the embryo.

21 Apr 2020

Researchers use genome-wide CRISPR technology to identify leukemia's weakness

A team of researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia, a type of cancer that remains difficult to treat and is marked by frequent relapse.

From UC San Diego 21 Apr 2020