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Rare inherited mutation in TP53 gene predisposes to a wide range of cancers

Rare inherited mutations in the body's master regulator of the DNA repair system – the TP53 gene – can leave people at a higher risk of developing multiple types of cancer over the course of their lives.

17 Jul 2020

Substances that target oxytocin receptors can help treat various diseases

Oxytocin is the so-called “cuddle hormone” or “love hormone” that plays a role in strengthening the relationship between the mother and child and controlling social bonding.

17 Jul 2020

Development of mammalian placenta depends upon simple twist of DNA

The development of the mammalian placenta depends upon an unusual twist that separates DNA's classic double helix into a single-stranded form, Yale researchers report July 15 in the journal Nature.

16 Jul 2020

Study shows genetic factors may influence the susceptibility to COVID-19

A new Cleveland Clinic study has identified genetic factors that may influence susceptibility to COVID-19. Published today in BMC Medicine, the study findings could guide personalized treatment for COVID-19.

16 Jul 2020

Researchers develop novel and promising approach for treatment of lung cancer

A new and promising approach for treatment of lung cancer has been developed by researchers at Lund University. The treatment combines a novel surgical approach with smart nanoparticles to specifically target lung tumors. The new study has been published in the July issue of Advanced Therapeutics.

16 Jul 2020

Oak coumarins could produce bitter taste in spirits,wine

Wine and spirits are complex mixtures of flavor and aroma compounds, some of which arise during aging in wooden barrels.

16 Jul 2020

Researchers develop novel technology to detect cancer biomarkers

A new way of identifying cancer biomarkers has been developed by researchers at Lund University in Sweden. The new technology allows very sensitive, quick and cost-effective identification of cancer biomarkers. The research is published in Nature Communication Biology.

16 Jul 2020

Imaging mass spectrometry identifies tumor markers for head and neck squamous cell carcinoma

Volume 11, Issue 28 of Oncotarget features "Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry" by Schmidt et. al. which reported that the authors used MALDI imaging mass spectrometry and immunohistochemistry to seek tumor-specific expression of proteins and lipids in HNSCC samples.

15 Jul 2020

Scientists develop new method to identify diseases by blood serum

Researchers of Peter the Great St.Petersburg Polytechnic University in collaboration with colleagues from Tsinghua University (China) developed a new dynamic light scattering method to determine the sizes of circulating immune complexes in blood serum.

15 Jul 2020

Healthy microbiome can reduce severity of chickungunya disease

Chikungunya virus, once confined to the Eastern Hemisphere, has infected millions of people in the Americas since 2013, when mosquitoes carrying the virus were discovered in the Caribbean.

15 Jul 2020

Umbilical cord blood treats children born with non-cancerous genetic disorders

Researchers at UPMC Children's Hospital of Pittsburgh found that infusing umbilical cord blood -- a readily available source of stem cells -- safely and effectively treated 44 children born with various non-cancerous genetic disorders, including sickle cell, thalassemia, Hunter syndrome, Krabbe disease, metachromatic leukodystrophy (MLD) and an array of immune deficiencies.

15 Jul 2020

HLA-G gene linked to male-to-female ratio at birth, survival of fetuses, and preeclampsia

Preeclampsia is globally a leading cause of illness and deaths among mothers and their babies. This severe pregnancy disorder occurs in up to five percent of all pregnancies.

15 Jul 2020

Stem cell treatment could improve the quality of donor kidneys

New research has demonstrated that kidneys can be revived prior to transplantation by delivering a cell therapy directly to the organ.

From Newcastle University 15 Jul 2020

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL.

15 Jul 2020

New link found between impaired brain energy metabolism and delirium

Scientists from Trinity College Dublin have discovered a new link between impaired brain energy metabolism and delirium - a disorienting and distressing disorder particularly common in the elderly and one that is currently occurring in a large proportion of patients hospitalized with COVID-19.

15 Jul 2020

UTHealth physicians study blood pressure drug's efficiency in improving COVID-19 outcomes

An interventional therapy aimed at improving survival chances and reducing the need for critical care treatment due to COVID-19 is being investigated by physicians at The University of Texas Health Science Center at Houston.

14 Jul 2020

The immune system can play a key role in improving recovery from heart attacks

International research collaboration to pioneer the field of immuno-cardiology and investigate ways to harness the power of the immune system to improve recovery from heart attacks will be led at the Perelman School of Medicine at the University of Pennsylvania by Jonathan Epstein, MD, executive vice dean, chief scientific officer and the William Wikoff Smith Professor of Cardiovascular Research.

14 Jul 2020

Study shows cathepsin B can be used as biomarker for traumatic brain injury

Scientists at the Walter Reed Army Institute for Research (WRAIR) have recently demonstrated that cathepsin B, a well-studied protein important to brain development and function, can be used as biomarker, or indicator of severity, for traumatic brain injury.

14 Jul 2020

Beta blockers can increase risk of heart failure in women more than men

Women taking beta blockers for hypertension with no prior history of cardiovascular disease (CVD) have a nearly 5% higher risk for heart failure than men when they present to hospital with acute coronary syndrome, according to new research published today in Hypertension, an American Heart Association journal.

14 Jul 2020

Less addictive opioid may have the ability to slow progression of osteoarthritis

A novel preclinical study by Keck Medicine of USC researchers, published in Arthritis & Rheumatology, reveals that a potential new opioid medication may have the ability to slow the progression of osteoarthritis while being less addictive than commonly prescribed opioid drugs.

14 Jul 2020