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Discovery could help break the cycle of rapid transmission of TB

Two strains of the bacterium causing tuberculosis have only minor genetic differences but attack the lungs in completely different fashion, according to Rutgers researchers.

18 Apr 2022

Spatial maps offer insights into the battle between melanoma cells and immune cells

Melanoma is a somewhat unusual cancer-;one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs.

From Harvard Medical School 15 Apr 2022

Gut viruses contribute to human health, but provoke inflammation when perturbed

Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine?

11 Apr 2022

Microcolonies in the GI tract comprise an important niche for cell-cell signaling and plasmid transfer

Published in Nature Communications, research from the University of Minnesota and Mayo Clinic sought to understand how microbial communities help people resist pathogens.

11 Apr 2022

New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)-;cells that support heart muscle contraction, generated in the lab from human stem cell lines-;which researchers say will improve approaches for disease modeling, regenerative therapies, and drug testing.

8 Apr 2022

Certain RNA molecules may serve as markers of cellular stress in different diseases

The body's ability to respond to various types of stress is essential for maintaining health, and failure of such adaptive stress responses can trigger or worsen numerous diseases.

6 Apr 2022

Researchers discover new type of cell that may play a key role in human lung diseases

A new type of cell that resides deep within human lungs and may play a key role in human lung diseases has been discovered by researchers at the Perelman School of Medicine at the University of Pennsylvania.

4 Apr 2022

RNA targeted by small molecule drugs, likely to create new pathways for disease treatment

RNA (ribonucleic acid) is involved in many aspects of human health, and a new study published in the journal Nature provides compelling evidence that RNA could be a promising pharmacological target.

1 Apr 2022

Gene mutation influences autism development, study finds

A research team discovered that interruption of a circadian clock gene may be implicated in the formation of autism spectrum disorder.

25 Mar 2022

Researchers create an atlas of cell types present in the white adipose tissue of humans, mice

Once considered to be inert, white adipose tissue is now recognized to be dynamic and to play an interactive role in a wide array of biological and metabolic processes.

21 Mar 2022

New research demonstrates genetic markers in leadership positions

The locations of nine core genetic markers related with leadership have been discovered in a recent study led by the National University of Singapore (NUS) Business School.

From National University of Singapore (NUS) 21 Mar 2022

Novel method to sneak large drug-carrying biological molecules into cells

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a novel method of delivering drugs into human cells using large biological molecules, by first encasing them in a protein-based microdroplet.

From Nanyang Technological University Singapore (NTU Singapore) 17 Mar 2022

Novel mechanistic insight into how gut bacteria work to tame intestinal inflammation

Bile acids made by the liver have long been known for their critical role in helping to absorb the food we ingest.

From Harvard Medical School 17 Mar 2022

Insight into oligodendrocyte cells could lead to new treatments for neurodegenerative diseases

New research may help scientists locate immature cells in the central nervous system that could shed light on the causes of neurodegenerative diseases like multiple sclerosis-;and autoimmune disease that affects the brain and nervous system-;and allow for the development of better therapeutic treatments.

14 Mar 2022

Researchers develop a method for preserving human primordial germ cell-like cells

Human primordial germ cells (PGCs) are the early precursors of the eggs (oocytes) and sperm that are necessary to keep humankind alive and reproducing.

11 Feb 2022

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

An international team led by the Case Western Reserve University School of Medicine has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn's disease and ulcerative colitis.

8 Feb 2022

New method helps distinguish bacterial DNA from human and other non-bacterial cells

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

4 Feb 2022

Cryobioprinting; A New Bioprinting Technique

In this interview, we speak to Dr. Y. Shrike Zhang about his latest bioprinting technique that allows tissues to be preserved for later use.

From Harvard Medical School 4 Feb 2022

Mother's unhealthy vaginal microbiome may contribute to mortality and altered development in babies

A new study in mice from University of Maryland School of Medicine researchers showed that an unhealthy vaginal microbiome in pregnant mothers in combination with an unhealthy diet contributed to increased pup deaths and altered development in the surviving babies.

28 Jan 2022

Study findings greatly expand the ability to engineer long-range genome edits

Researchers discovered the potential of CRISPR, a tool used by bacteria to defend themselves against viral intruders, nearly a decade ago.

24 Jan 2022