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Specific metabolites can predict COVID-19 mortality

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

28 Oct 2020

Scientists develop human airway stem cells to accelerate research on COVID-19, influenza

For the first time, researchers have successfully created airway basal stem cells in vitro from induced pluripotent stem cells by reprogramming blood cells taken from patients.

27 Oct 2020

Scientists develop lab-grown lung model to study SARS-CoV-2 infection

A team of Duke University researchers has developed a lab-grown living lung model that mimics the tiny air sacs of the lungs where coronavirus infection and serious lung damage take place. This advance has enabled them to watch the battle between the SARS-CoV-2 coronavirus and lung cells at the finest molecular scale.

23 Oct 2020

Researchers develop "mini lungs" to study SARS-CoV-2 infection

'Mini-lungs' grown from tissue donated to Cambridge hospitals has provided a team of scientists from South Korea and the UK with important insights into how COVID-19 damages the lungs.

23 Oct 2020

Researchers uncover a new cellular mechanism for disposing of misfolded proteins

About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin (AAT) deficiency present with high variation in the severity of liver disease.

21 Oct 2020

Computational study of the structure and dynamics of glycosylated SARS-CoV-2

SARS-CoV-2 has been shown to enter cells by interaction with ACE2, which is found on the surface of cells in the lungs and throughout the body.

21 Oct 2020

SARS-CoV-2 may induce long-term autoimmune disorder due to self-glycan antibody production

A new study indicated that many of the unusual symptoms of SARS-CoV-2 infections may be due to induced autoimmune responses.

20 Oct 2020

Biofilms of major pathogenic bacteria can deform soft surfaces

The vast majority of bacteria in the world live on surfaces by forming structures called "biofilms". These communities host thousands to millions of bacteria of different types, and are so biologically complex and active that scientists describe them as "cities".

9 Oct 2020

Researchers develop new testing platform for breast cancer cells

A Purdue University team has developed a novel testing platform to evaluate how breast cancer cells respond to the recurrent stretching that occurs in the lungs during breathing.

7 Oct 2020

MIT engineers develop a method to turn off specific genes in bone marrow cells

Using specialized nanoparticles, MIT engineers have developed a way to turn off specific genes in cells of the bone marrow, which play an important role in producing blood cells.

From Massachusetts Institute of Technology (MIT) 6 Oct 2020

Researchers identify a promising treatment for COVID-19 infection

An effective method for treating the 2003 SARS epidemic, also works on the closely associated SARS-CoV-2 virus.

5 Oct 2020

Researchers identify specific cellular pathway involved in the regeneration of lung tissue

Scientists have discovered a new cellular pathway that can be targeted with a naturally occurring medication to activate the regeneration of lung tissue.

30 Sep 2020

T-cell-based vaccine strategy provides broader protection against influenza

As Americans begin pulling up their sleeves for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternative vaccine approach that provides broader protection against seasonal influenza.

24 Sep 2020

Research finds air pollution particles in the placentas of women

Pollution particles, including metals, have been found in the placentas of fifteen women in London, according to research led by Queen Mary University of London.

24 Sep 2020

Druggable pocket in SARS-CoV-2 Spike protein can help eliminate COVID-19

Researchers have identified a druggable pocket in the SARS-CoV-2 Spike protein that could be utilized to prevent the virus from infecting human cells.

24 Sep 2020

Elderly patients face higher risk of severity and death from COVID-19

SARS-CoV-2 can infect people of any age. However, elderly people face a greater risk of severity and death when compared to younger patients.

22 Sep 2020

Sticky DNA webs may cause tissue damage linked to severe COVID-19

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published on September 14 in the Journal of Experimental Medicine (JEM).

15 Sep 2020

New study reveals metabolic signature of SARS-CoV-2 infection involving signs of multi-organ damage

SARS-CoV-2 can lead to a broad range of symptoms, from absolutely nothing to multi-organ failure, severe respiratory stress, and eventually death.

11 Sep 2020

Researchers review the role of macrophage activation syndrome in COVID-19

A major percentage of COVID-19 cases have become so severe that hospital admissions have become mandatory for both monitoring and treatment.

10 Sep 2020

Novel method produces anti-inflammatory substances with controlled quality

Anti-inflammatory substances based on components of human cells could one day improve treatment in patients. Researchers at the Institute of Pharmacy at Martin Luther University Halle-Wittenberg (MLU) have developed a method for producing those substances with controlled quality.

10 Sep 2020