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Identifying the Genetic Variant That Increases Disease Severity in MS

Research of over 22,000 patients with multiple sclerosis (MS) has for the first time discovered a genetic variant linked with speedier progression of the disease, a buildup of disability that can deprive patients of their mobility and independence over time.

29 Jun 2023

The First Programmable RNA-Guided System in Eukaryotes Uncovered

Feng Zhang of the Broad Institute at MIT and Harvard and the McGovern Institute for Brain Research at MIT headed a team of researchers who discovered the first programmable RNA-guided mechanism in eukaryotes, which include fungi, plants, and animals.

29 Jun 2023

Mechanisms of MCL-1 Inhibitor-Induced MCL-1 Protein Upregulation and Induction of Apoptosis

A new editorial paper was published in Oncotarget's Volume 14 on June 21, 2023, entitled, "Decoding the mechanism behind MCL-1 inhibitors: A pathway to understanding MCL-1 protein stability."

29 Jun 2023

Study Examines Neural Activity and Wake-Like Skin Patterning of Octopus During Their Sleep

When octopuses sleep, their quiet periods of slumber are punctuated by short bursts of frenzied activity. Their arms and eyes twitch, their breathing rate quickens, and their skin flashes with vibrant colors.

29 Jun 2023

New Study Sets the Stage to Help People Maintain Weight Loss After Dieting

Researchers led by McMaster University professor Gregory Steinberg and postdoctoral research fellow Dongdong Wang have uncovered a key mechanism for promoting weight loss and maintaining the burning of calories during dieting.

29 Jun 2023

Analyzing Glioma Progression and Implicating CPNs’ Long-Range Projections

Glioblastoma (GBM) is the most aggressive and lethal form of brain tumor. Despite treatment, GBM recurrence is inevitable and tends to occur outside surgical margins or in locations remote to the primary tumor, highlighting the central role played by tumor infiltration in this malicious disease.

29 Jun 2023

Understanding Mammary Biology That May Help Find Therapeutic Targets for Breast Cancer

A new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world's largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer.

29 Jun 2023

New Breakthrough of Genetic Marker Improves Treatment for Multiple Sclerosis

A study of more than 22,000 people with multiple sclerosis has discovered the first genetic variant associated with faster disease progression, which can rob patients of their mobility and independence over time.

29 Jun 2023

Analyzing the Role of Pyroptosis in Improving the Treatment of Lung Cancer

Lung cancer, one of the most aggressive forms of cancer, continues to be a leading cause of death worldwide. Although several new therapies have been developed for this disease, it has a poor prognosis in its advanced stages.

29 Jun 2023

New Nanoparticle Developed Helps Improve the Delivery of mRNA-Based Vaccines

Johns Hopkins Medicine scientists say they have developed a nanoparticle -; an extremely tiny biodegradable container -; that has the potential to improve the delivery of messenger ribonucleic acid (mRNA)-based vaccines for infectious diseases such as COVID-19, and vaccines for treating non-infectious diseases including cancer.

29 Jun 2023

Disclosing the Key Role of Mitofusin 2 Cellular Makeup in Interconnecting Organelles Within Cells

Researchers at IRB Barcelona, the University of Barcelona (UB), VIMM, and the University of Padua unveil the key role of Mitofusin 2 cellular makeup in interconnecting organelles within cells.

29 Jun 2023

New AI-Assisted Methods to Discover Novel Deaminase Proteins with Unique Functions

At the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, GAO Caixia’s group has introduced the use of artificial intelligence (AI)-assisted techniques to find out novel deaminase proteins with special functions via structural prediction and classification.

28 Jun 2023

New View of Euchromatin in the Cell Analyzed

In their study performed, the research group discusses their novel view of euchromatin present in the cell and displays how the disclosed organization is appropriate to genome functions.

28 Jun 2023

The Influence of Streptomyces on Soil Microorganisms

Chemical substances called arginoketides, which are produced by bacteria of the genus Streptomyces, cause a variety of reactions in other microorganisms: Algae group together to form aggregates, fungi produce signaling molecules that they would not otherwise produce, and bacteria develop biofilms that cause other organisms to respond differently.

28 Jun 2023

Cell Fate Conversion Plays Crucial Role in Cancer Research

Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin and the Centre for Genomic Regulation (CRG) in Barcelona have discovered how cells speed changes to their identity known as “cell fate conversion.”

28 Jun 2023

Squid-Inspired Soft Film Could Revolutionize Health Monitoring and Temperature Management

With a flick of a switch, current technologies allow you to quickly change materials from being dark to light, or cold to hot, just by blocking or transmitting specific wavelengths.

28 Jun 2023

Probiotic Bacteria may Help Maintain Brain Function in Aging Nematodes

A group from Nagoya University in Japan has discovered that when the diet of nematodes, tiny worms measuring about a millimeter or less in length, includes the bacteria Lactobacillus reuteri, the weakening of associative learning ability caused by aging does not occur.

28 Jun 2023

Research News and Research

Identifying the Genetic Variant That Increases Disease Severity in MS

The First Programmable RNA-Guided System in Eukaryotes Uncovered

Mechanisms of MCL-1 Inhibitor-Induced MCL-1 Protein Upregulation and Induction of Apoptosis

Study Examines Neural Activity and Wake-Like Skin Patterning of Octopus During Their Sleep

New Study Sets the Stage to Help People Maintain Weight Loss After Dieting

Analyzing Glioma Progression and Implicating CPNs’ Long-Range Projections

Understanding Mammary Biology That May Help Find Therapeutic Targets for Breast Cancer

New Breakthrough of Genetic Marker Improves Treatment for Multiple Sclerosis

Analyzing the Role of Pyroptosis in Improving the Treatment of Lung Cancer

New Nanoparticle Developed Helps Improve the Delivery of mRNA-Based Vaccines

Disclosing the Key Role of Mitofusin 2 Cellular Makeup in Interconnecting Organelles Within Cells

New AI-Assisted Methods to Discover Novel Deaminase Proteins with Unique Functions

New View of Euchromatin in the Cell Analyzed

The Influence of Streptomyces on Soil Microorganisms

Cell Fate Conversion Plays Crucial Role in Cancer Research

Squid-Inspired Soft Film Could Revolutionize Health Monitoring and Temperature Management

Probiotic Bacteria may Help Maintain Brain Function in Aging Nematodes

Teijin Frontier Introduces New Nonwoven Microcarriers for Speedy and Large-scale Cell Culture

Discovering a Major Factor Causing Aggressive Cancer

Chloroplast Size Manipulation Unlikely to Boost Crop Photosynthesis

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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