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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

New gene therapy approach can improve uterine blood flow in placental insufficiency

A new study identified an adenovirus gene therapy vector carrying a VEGF isoform. It can improve uterine blood flow in placental insufficiency, as reported in the peer-reviewed journal Human Gene Therapy.

16 Dec 2020

Researchers develop genetic markers to monitor herring populations and avoid overfishing

An international team of Swedish, Norwegian, Danish and Irish scientists has used whole-genome sequencing to characterize 53 herring populations from the Atlantic Ocean and the Baltic Sea.

16 Dec 2020

Tumor's stiff-arm tactic restricts the effectiveness of checkpoint inhibitors

In a paper just published in the Journal for the Immunotherapy of Cancer (doi:10.1136/jitc-2020-001712), Dr. Herbert, Head of Discovery at InsideOutBio, asks whether cancer cells stiff-arm immune cells just like rugby players push off defenders from the other team.

16 Dec 2020

New genomic tool can accurately assess the risk of breast cancer

Breast cancer is the most commonly diagnosed disease in women and is the main cause of cancer-related mortalities in this group of population.

15 Dec 2020

Study sheds new light on a genetic developmental disorder

The rare hereditary developmental disorder, called Meier-Gorlin syndrome, or MGS for short, causes dwarfism, missing patella, a small brain, small ears, and other skeletal abnormalities. This condition leads to stillbirths and miscarriages in severe cases.

15 Dec 2020

New study dispels concerns that human stem cells contain cancer-causing mutations

Pioneering new research has made a pivotal breakthrough that dispel concerns that human stem cells could contain cancer-causing mutations.

From University of Exeter 15 Dec 2020

Researchers provide a list of genes implicated in congenital heart disease

Over two million babies, children, and adults in the United States are living with congenital heart disease--a range of birth defects affecting the heart's structure or function.

15 Dec 2020

Using genetic engineering to grow synthetic livers

News-Medical talks to Dr. Mo Ebrahimkhani about his research using genetic engineering together with a machine-learning algorithm to mature a lab-grown 'designer liver organoid'.

From University of Pittsburgh 15 Dec 2020

New combination therapy could be effective in treating aggressive cancers with common mutations

Scientists have long known that therapies that target the cancer-driving MAPK pathway are only effective in a handful of cancers with specific mutations in a cancer gene called BRAF, and these cancers that initially respond to the therapy often end up developing resistance to the treatment, resulting in relapse for many patients.

15 Dec 2020

Newly identified diagnostic marker can help overcome treatment resistance in cervical cancer

Scientists from the University of California, Los Angeles have discovered a promising diagnostic marker that may help predict the response of cervical cancer patients to standard radiation and chemotherapy treatments.

14 Dec 2020

Study elucidates genes responsible for Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue.

14 Dec 2020

Researchers discover protein crucial for growing life-saving blood stem cells

A group of scientists from the Centre for Genomic Regulation (CRG) in Barcelona and Columbia University in New York City has discovered a protein that is crucial for expanding the usually scarce, life-saving blood stem cells.

11 Dec 2020

Scientists aim to treat and prevent disease by understanding exercise benefits

A top exercise researcher and colleagues at the University of Virginia School of Medicine have launched an ambitious effort to understand the whole-body benefits of exercise so that doctors can use that information to prevent and treat disease.

11 Dec 2020

New model helps assess the effect of epigenetic changes on gene expression

Researchers have developed a mathematical model to quantitatively assess the impacts of particular epigenetic changes on the transcription rates.

11 Dec 2020

Newly identified Cas9 nucleases can improve genome editing

Scientists have explained two new compact Cas9 nucleases that will possibly extend the Cas9 toolbox for genome editing.

11 Dec 2020

A genetic shortcut to help visualize proteins at work

A group at Gladstone Institutes and UC San Francisco (UCSF) has demonstrated that a large-scale and systematic genetic approach can indeed yield reliable and detailed information on the structure of protein complexes.

11 Dec 2020

Study shed light on how genes affect the risk for coronary artery disease

Researchers at the University of Virginia have shed light on how our genes affect our risk for coronary artery disease, the most common form of heart disease.

11 Dec 2020

Researchers identify new therapeutic target to treat type 1 diabetes

Scientists from the University of Utah School of Medicine have discovered a novel therapeutic target to treat type 1 diabetic patients.

10 Dec 2020

Genetically modified tomato can provide a new source of Parkinson’s disease drug

L-DOPA is a drug used for treating Parkinson’s disease, and now researchers have created a tomato that is enriched with this drug. This innovation could lead to a new, inexpensive source of one of the most essential medicines in the world.

10 Dec 2020

Study sheds light on molecular underpinnings of long-term memory

On a late summer day in 1953, a young man who would soon be known as patient H.M. underwent experimental surgery.

From Harvard Medical School 10 Dec 2020

Gene News and Research

Further Reading

New gene therapy approach can improve uterine blood flow in placental insufficiency

Researchers develop genetic markers to monitor herring populations and avoid overfishing

Tumor's stiff-arm tactic restricts the effectiveness of checkpoint inhibitors

New genomic tool can accurately assess the risk of breast cancer

Study sheds new light on a genetic developmental disorder

New study dispels concerns that human stem cells contain cancer-causing mutations

Researchers provide a list of genes implicated in congenital heart disease

Using genetic engineering to grow synthetic livers

New combination therapy could be effective in treating aggressive cancers with common mutations

Newly identified diagnostic marker can help overcome treatment resistance in cervical cancer

Study elucidates genes responsible for Glioblastoma invasiveness

Researchers discover protein crucial for growing life-saving blood stem cells

Scientists aim to treat and prevent disease by understanding exercise benefits

New model helps assess the effect of epigenetic changes on gene expression

Newly identified Cas9 nucleases can improve genome editing

A genetic shortcut to help visualize proteins at work

Study shed light on how genes affect the risk for coronary artery disease

Researchers identify new therapeutic target to treat type 1 diabetes

Genetically modified tomato can provide a new source of Parkinson’s disease drug

Study sheds light on molecular underpinnings of long-term memory

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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