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Enzyme in fruit fly larvae plays key role in waking up brain stem cells

Researchers studying an enzyme in fruit fly larvae have found that it plays an important role in waking up brain stem cells from their dormant 'quiescent' state, enabling them to proliferate and generate new neurons.

12 Feb 2021

Researchers identify tumor suppressor gene involved in stress response

Even the larvae of the Drosophila fly contain adult progenitor cells. And these cells are the only ones that are preserved throughout the growth and are responsible for the development of adult tissues and organs.

11 Feb 2021

Researchers uncover clues to why some corals are resistant to bleaching

Coral reefs are beautiful and diverse ecosystems that power the economies of many coastal communities. They're also facing threats that are driving their decline, including the planet's warming waters.

9 Feb 2021

Researchers identify three genes regulating stemness of gastric tissue stem cells

Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages.

9 Feb 2021

Detecting the levels of antibiotics in food

In this interview, AZoLifeSciences speaks to Dr. Yujie Ben about her latest research that investigated the varying levels of antibiotics found in food.

From Southern University of Science and Technology 8 Feb 2021

Researchers explore the regulatory role of protein in human health and disease

Researchers from the University of Virginia, Lehigh University and the Massachusetts Institute of Technology are pooling their respective labs' expertise to unlock the mysteries of a protein that plays a critical regulatory role in human health and disease.

5 Feb 2021

3D genome study reveals molecular regulatory mechanisms of human brain evolution

A team led by Prof. SU Bing from the Kunming Institute of Zoology (KIZ) of the Chinese Academy of Sciences (CAS), Prof. LI Cheng from Peking University, and Prof. ZHANG Shihua from the Academy of Mathematics and Systems Science of CAS has reported the highest resolution by far of the 3D genome of the primate brain, and demonstrated the molecular regulatory mechanisms of human brain evolution through cross-species multi-omics analysis and experimental validation. The study was published in Cell.

29 Jan 2021

Unique proteomics-based technology can help diagnose breast cancer more accurately

Breast cancer could be identified more precisely than existing methods using blood specimens and exclusive proteomics-based technology.

28 Jan 2021

Two enzymes drive pre-cancer stem cells into malignancy

Since stem cells can continually self-regenerate, making more stem cells, and differentiate into many different specialized cell types, they play an important role in our development and health.

From UC San Diego 27 Jan 2021

Study shows why obese mothers tend to have children susceptible to metabolic diseases

A Brazilian study published in the journal Molecular Human Reproduction helps understand why obese mothers tend to have children with a propensity to develop the metabolic disease during their lifetime, as suggested by previous research.

27 Jan 2021

Protein phosphatase inhibition could contribute to the treatment of cancer, other diseases

The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential.

13 Jan 2021

Researchers create molecular ON-OFF switches to regulate CAR T cell activity

CAR T cells are a breakthrough class of effective but often toxic cancer therapies. To prevent overactivation, switchable CAR T cells were engineered that can be turned on and off with an approved, widely used cancer drug.

7 Jan 2021

Scientists show how plants adapt root growth to varying sources of nitrogen

Nitrogen is one of the most essential nutrients for plants. Its availability in the soil plays a major role in plant growth and development, thereby affecting agricultural productivity.

6 Jan 2021

Transporter protein likely played a crucial role in vertebrate evolution

A transporter protein that regulates cell membrane cholesterol likely played an important role in vertebrate evolution, according to a review published by iCeMS researchers in the journal FEBS Letters.

24 Dec 2020

Scientists discover molecular defects associated with rare genetic disorder in children

Damien D'Amours and his team at the Ottawa Institute of Systems Biology needed three years to discover the molecular defects associated with the LIC Syndrome, a serious genetic disorder that affects young children and result in acute respiratory distress, immune deficiency and abnormal chromosomes.

23 Dec 2020

Biochemical methods reveal signal transduction mystery inside human pathogen

In order to adapt to the changing environment, bacteria must quickly transform extracellular information into appropriate intracellular reactions. Two component system (TCS) is the main signal transduction protein in prokaryotic cells to transform environmental stimuli into cellular responses.

16 Dec 2020

Study shed light on how genes affect the risk for coronary artery disease

Researchers at the University of Virginia have shed light on how our genes affect our risk for coronary artery disease, the most common form of heart disease.

11 Dec 2020

Researchers use new decoding method to identify novel proteins encoded by HSV-1

Comprehensive identification of viral proteins encoded by viral genes is required to understand the pathophysiology of viral infections.

8 Dec 2020

Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells' ability to eliminate blood cancers, according to new preclinical data from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center.