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Researchers identify a promising biomarker to screen stem cell quality

Published recently in the Stem Cells journal, a new study addresses a major issue that has been challenging the human mesenchymal stem cells (hMSCs) therapy.

9 Jun 2020

Understanding protein-coding gene's role in IBD

A protein-coding gene associated with autoimmune diseases such as Crohn's disease and ulcerative colitis, collectively referred to as inflammatory bowel disease, or IBD, will be the focus of new research in the School of Medicine at the University of California, Riverside.

9 Jun 2020

Study investigates how cancer adapts its metabolism to overcome treatment

Knowing what cancer will do next could lessen the likelihood of it becoming resistant to treatment. A new Canadian study investigates how cancer adapts its metabolism to potentially overcome therapies still in development.

From University of Toronto 9 Jun 2020

CD8+ T cells can help develop vaccines against Japanese encephalitis, Zika fever

A clinical case of Japanese encephalitis is diagnosed in over 68,000 individuals every year, leading to the death of one in four of these affected patients.

8 Jun 2020

Study shows how a fat cell's immune response exacerbates obesity

When obesity occurs, a person's own fat cells can set off a complex inflammatory chain reaction that can further disrupt metabolism and weaken immune response--potentially placing people at higher risk of poor outcomes from a variety of diseases and infections, including COVID-19.

8 Jun 2020

New technology to rapidly create antibody-drug conjugates

A USC School of Pharmacy-led team has engineered a new, faster way to make drugs that precisely target malignant cells - while leaving healthy tissue undamaged - that could lead the way to better treatments for numerous types of cancer.

5 Jun 2020

C19ORF57 gene could advance reproductive medicine

The gene C19ORF57 has been identified to play a major role in meiosis by the Institute of Molecular Embryology and Genetics at Kumamoto University.

5 Jun 2020

Genomic research can help combat COVID-19

Next-generation sequencing of the COVID-19 virus is providing powerful metagenomic data, which, combined with clinical data, will inform the search for effective treatments, as reported in the peer-reviewed journal Pediatric Allergy, Immunology, and Pulmonology.

5 Jun 2020

Human protein plays crucial role in transcription and genome integrity

Researchers from the University of Seville and Cabimer discover that the UAP56/DDX39B protein remove DNA-RNA hybrids from the genome.

5 Jun 2020

New technique restores hearing in mice with a recessive genetic mutation

Using a new genetic engineering technique, known as base editing, researchers from Boston Children's Hospital and the Broad Institute of MIT and Harvard, have restored hearing in mice with a known recessive genetic mutation.

5 Jun 2020

Lab-grown organoids can prevent hair loss

Researchers have created a new, hair-germinating piece of human skin in the laboratory that might prevent hair loss in the days to come.

4 Jun 2020

‘Terminator’ protein halts tumorigenesis

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

4 Jun 2020

Building blocks of DNA and RNA could have co-existed in the primordial Earth

Scientists have long debated which genetic information carrier - DNA or RNA - started life on Earth, but a new study suggests life could have begun with a bit of both.

4 Jun 2020

Researchers deconstruct complex mechanisms that control tissue repair

ETH researchers have deconstructed the mechanisms that control wound healing and scar formation in more detail.

4 Jun 2020

Bacteria that live in soil and on people have widespread antibiotic-destroying genes

The latest generation of tetracyclines - a class of powerful, first-line antibiotics - was designed to thwart the two most common ways bacteria resist such drugs.

3 Jun 2020

Dramatic increase in immune cells in mouse lungs after birth may help protect against infections

An explosion in the number and types of immune cells in the lungs of newborn mice likely helps them adapt to breathing and protects them from infection, says a new study published today in eLife.

3 Jun 2020

Scientists decode ancient DNA extracted from Dead Sea Scrolls

An interdisciplinary team from Tel Aviv University, led by Prof. Oded Rechavi of TAU's George S. Wise Faculty of Life Sciences, Prof. Noam Mizrahi of TAU's Department of Biblical Studies, in collaboration with Prof. Mattias Jakobsson of Uppsala University in Sweden, the Israel Antiquities Authority and Prof. Christopher E. Mason of Weill Cornell Medicine, has successfully decoded ancient DNA extracted from the animal skins on which the Dead Sea Scrolls were written.

3 Jun 2020

Do Chemical Pollutants Increase the Risk of Celiac Disease?

Do chemical pollutants increase the risk of celiac disease? AZoLifeSciences spoke to Abigail Gaylord and Dr. Jeremiah Levine to find out.

From New York University (NYU) 3 Jun 2020

A remote optical stimulation for neural cells

A team led by researchers at Carnegie Mellon University has created a new technology that enhances scientists' ability to communicate with neural cells using light.

2 Jun 2020

Stem cell model sheds new light on neurodegeneration process

A new study published today in Neuron led by The New York Stem Cell Foundation Research Institute's Valentina Fossati, Ph.D., creates astrocytes - an integral support cell in the brain - from stem cells and shows that in disease-like environments, these normally helpful cells can turn into neuron-killers.

2 Jun 2020