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Native genome model of a “live” virus replicated

An Aston University scientist has developed the world’s first computer reconstruction of a virus, complete with its native genome.

24 Jan 2023

Study suggests new strategies for controlling plant biochemistry

Plant biochemists at the U.S. Department of Energy's Brookhaven National Laboratory have discovered a new level of regulation in the biochemical "machinery" that plants use to convert organic carbon derived from photosynthesis into a range of ring-shaped aromatic molecules.

12 Jan 2023

Analyzing the regulatory mechanisms of enzyme production in mold

Filamentous fungi have long been a close ally of sake brewers, but they may soon become associates of environmentalists as well. Scientists from Osaka Metropolitan University discovered the regulatory mechanisms of enzyme synthesis in a filamentous fungus, allowing for the effective degradation of plant biomass, an alternative energy resource to petroleum.

11 Jan 2023

Effective anticancer strategy for selective killing of cancer cells

A study team headed by Dr Yuanliang Zhai from The University of Hong Kong’s (HKU) School of Biological Sciences and his associates from The Hong Kong University of Science and Technology (HKUST) and Institut Curie in France discovered a new mechanism of the human MCM2-7 complex in controlling replication initiation, which can be employed as a unique and effective anticancer method with the potential for selective death of cancer cells.

11 Jan 2023

Discovery of a new cellular element crucial to sense of smell

Researchers at Umeå University have found an organelle, a previously unidentified cellular component, inside the neurons that are responsible for the ability to smell. The finding might have repercussions for future studies on COVID-19 symptoms like impaired smell sense.

5 Jan 2023

Structure of the complete virion of S. epidermidis–infecting phage revealed

Scientists from the University of Alabama at Birmingham used cryo-electron microscopy to reveal the structure of a bacterial virus in extraordinary detail.

20 Dec 2022

Small fluorescent protein helps researchers to capture deeper, more precise biomedical images

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

7 Dec 2022

The analysis of pesticide residues in cannabis and hemp products

In this interview, Avinash Dalmia, the Senior Principal Application Scientist at PerkinElmer, talks to AZoLifeSciences about the analysis of 102 pesticides and 5 mycotoxin residues in hemp regulated by colorado state.

From PerkinElmer 2 Dec 2022

Tankyrase protein plays an important role in helping drive bowel cancer

The inner workings of the main protein involved in an extensive range of cellular processes have been disclosed by researchers. This possibly sets the stage for improved and less toxic cancer drugs.

25 Nov 2022

Providing structural understanding of the influenza virus

The structure of the influenza replication machinery and how it interacts with cellular proteins have been solved by a team of Oxford University scientists using a variety of techniques at Diamond Light Source.

8 Nov 2022

New bioprinting platform to replicate tumors in 3D spheroids

Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumors in 3D models.

3 Nov 2022

Structure of phycobilisomes of cyanobacterium revealed

Researchers of RIKEN identified the structure of the “antenna” that a blue-green alga employs to yield light and compared it with those of four other species.

1 Nov 2022

Resistance against Epstein-Barr virus from experimental monoclonal antibodies

When tested in a lab setting using human cells, a panel of experimental monoclonal antibodies (mAbs) that target various Epstein-Barr virus (EBV) sites prevented infection.

1 Nov 2022

Identifying the structure of the SEA complex

The mTOR protein is important for cell growth, proliferation, and survival. Its activity fluctuates according to nutrient availability and growth factors like hormones.

1 Nov 2022

Innovative strategy for studying membrane proteins

Membrane proteins are vital therapeutic targets. They exist between the interior and exterior of human cells. Some of them, known as “transporters,” transport substances into and out of the cellular environment.

26 Oct 2022

Molecular insights into the photosynthesis process

The most essential foundation of life on Earth is photosynthesis. Plants and single-celled algae use sunlight’s energy to turn it into sugar and biomass.

17 Oct 2022

The strategy used by metastatic cancer cells to invade the liver identified

The alternative pathway for liver metastasis has been revealed by a team of researchers.

5 Oct 2022

Newly isolated Bacteroides likely to be present in mammals beyond mice

In the DFG-funded Collaborative Research Center (CRC) 1182 “Origin and Function of Metaorganisms,” scientists from Kiel University and the Max Planck Institute for Evolutionary Biology in Plön (MPI-EB) are investigating the evolutionary history and function of Bacteroides.

From The Max Planck Institute 30 Sep 2022

Cryo-EM solves the decades-old mystery of bacterial movement

Scientists from the University of Virginia School of Medicine and their colleagues have discovered a decades-old mystery regarding how E. coli and other bacteria move.

28 Sep 2022

Modification of the lignin “chemical code”

According to a recent study, it is possible to genetically alter the lignin chemistry of plants to improve their ability to recover from drought without compromising the size of the plant or seed production.

22 Sep 2022