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Parasite infection associated with the overall composition of gastrointestinal microbiome

Parasite infections are a constant presence for many people who live in tropical regions, particularly in less industrialized areas.

15 Jun 2020

Cardiac organoids that closely mimic physiological conditions during a heart attack

In the U.S., someone has a heart attack every 40 seconds, and yet researchers have not had a model that fully mimics what occurs in the human heart after a heart attack.

12 Jun 2020

Human stem cell models reveal neurodegeneration in glaucoma

Glaucoma, a serious eye condition responsible for causing vision loss, affects over three million Americans.

12 Jun 2020

Protein glycosylation plays a major role in DNA methylation

An underlying principle in molecular biology is that “DNA makes RNA makes protein.” The process of gene expression is firmly controlled in various ways.

12 Jun 2020

Researchers create a new model to study early stage of human development

Researchers from the University of Cambridge have devised a new model to analyze an early stage of human development through human embryonic stem cells.

12 Jun 2020

Baylor researchers uncover a novel mechanism that triggers cellular immune response

Viruses and other disease-causing microbes influence the type of immune response their hosts will develop against them. In some cases, the predominant response involves antibodies, proteins made by the immune system that specifically recognize parts of the invading microbe and mediate its destruction.

12 Jun 2020

Overactive enzyme causes an inherited form of hypertension

A Turkish family from a village near the Black Sea first caught the attention of medical researchers in the early 1970s.

12 Jun 2020

New study may lead to novel treatments for heart and liver diseases

A study that closely analyzed the cardiac health of flies offers new evidence that dysfunction in the liver may result in the deterioration of the heart.

11 Jun 2020

Stress-induced chemoresistance is linked to changes in cellular metabolism

There is a wide range of mechanisms related to chemoresistance, a majority of which are yet to be fully understood.

11 Jun 2020

Researchers identify how certain gene mutations cause ALS

Researchers at the University of Maryland School of Medicine have identified how certain gene mutations cause amyotrophic lateral sclerosis, also known as Lou Gehrig's disease.

11 Jun 2020

Researchers identify genes involved in the development of malignant brain tumor

Researchers have developed a new approach to identify functional mutations and their impact on genes applicable to the development of malignant brain tumors.

10 Jun 2020

Study reveals the role of Cpeb4 protein involved in bone and joint diseases

Osteoclasts are bone-dissolving cells that are extracted from a type of immune cell referred to as macrophages which are required for the maintenance of bones.

10 Jun 2020

Cellular mechanophenotyping may help better understand tumor cells

Our ability to predict who will get cancer, how a patient will respond to treatment, or if a patient will relapse is still quite limited. Despite advances in the detection of genetic mutations and the establishment of risk factors, such as age and genetic variants, it remains a great scientific and medical challenge.

10 Jun 2020

KAUST scientists reveal the genetic metronome within malaria parasites

The parasites responsible for malaria seem to march to their own beat.The mystery behind the molecular basis of how these parasites synch their rhythm in replication to the host's clock-driven rhythms has been solved.

10 Jun 2020

RDP1 gene regulates the production of pollen grains

An international study has discovered a gene in the plant model Arabidopsis that reduces the number of pollen grains.

9 Jun 2020

Study investigates how cancer adapts its metabolism to overcome treatment

Knowing what cancer will do next could lessen the likelihood of it becoming resistant to treatment. A new Canadian study investigates how cancer adapts its metabolism to potentially overcome therapies still in development.

From University of Toronto 9 Jun 2020

DNA damage and repair jointly shape mutational signatures

A collaborative project between the Center for Genome Integrity, within the Institute for Basic Science, and the Dundee School of Life Sciences, the EMBL's European Bioinformatics Institute, and the Wellcome Sanger Institute have screened almost 163,000 DNA mutations in 2,700 C. elegans roundworms to shed light on DNA damage.

9 Jun 2020