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Using High-Energy X-Rays to Image Biological Specimens Without Damage

A pollen grain showing the nanofoam within or a diatom with the individual geometric structures inside clearly visible: Using high-energy X-rays from the PETRA III synchrotron light source at DESY, a team led by CFEL scientists Saša Bajt and Henry Chapman has managed to image these structures without damaging them.

31 May 2023

New Algorithm to Improve the Understanding of Protein Movements

Proteins are biological molecules that perform almost all biochemical tasks in all forms of life. In doing so, the tiny structures perform ultra-fast movements.

31 May 2023

Computational Approach Could Uncover Transcriptional Regulatory Mechanisms and Causal Noncoding Variants

Less than two percent of the human genome codes for proteins, with the rest being noncoding and likely helping with gene regulation.

31 May 2023

High-Resolution, Stable Brain Stimulation by Ultraflexible Nanoelectrodes

Conventional implantable medical devices designed for brain stimulation are often too rigid and bulky for what is one of the body's softest and most delicate tissues.

31 May 2023

Almond Milk Yogurt has a Better Nutritional Profile Than Dairy and All Other Plant-Based Yogurts

In a nutritional comparison of plant-based and dairy yogurts, almond milk yogurt came out on top, according to research led by a University of Massachusetts Amherst food science major.

31 May 2023

Charting a High-Resolution Roadmap for Regeneration of Pancreatic β Cells

At the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences (CAS), a research group headed by Professor Zhen Shao and the collaborators plotted a high-resolution roadmap for the process of pancreatic β cell regeneration by in vivo transdifferentiation from adult acinar cells with the help of a single-cell RNA sequencing (scRNA-seq) technology.

31 May 2023

Ancient DNA Reveals Earliest Evidence of Plague Cases in Britain

The Francis Crick Institute has discovered three 4,000-year-old British cases of Yersinia pestis, the bacteria that causes the plague—the oldest evidence of the plague in Britain to date. The study was published in Nature Communications.

31 May 2023

Characterizing a Pivotal Time in Mammalian Embryonic Development

Many of life’s secrets are hidden in the initial stages of embryonic development. Unraveling these mysteries can aid in the understanding of early development and birth abnormalities, as well as the creation of innovative regenerative medicine treatments.

31 May 2023

Determining Disease Progression in Patients with Recent-Onset Type 1 Diabetes

A gene expression signature that has the potential to forecast the advance of type 1 diabetes has been determined by scientists from Turku Bioscience Centre and InFLAMES Flagship at the University of Turku in Finland.

30 May 2023

New Genes Associated With SCAD Identified

The National Institute for Health and Care Research (NIHR) Leicester Biomedical Research Centre (BRC) and Universite Paris Cite have identified new genes linked with an increased incidence of a type of heart attack that primarily affects young to middle-aged women, with support from global partners in Canada, the United States, and Australia.

30 May 2023

Researchers Develop Novel Metal-Protein Hybrid Complex With Enhanced ROS Activity

Cu(II) complexes with low molecular weight are functional superoxide-dismutase (SOD) models with superior reactive oxygen species (ROS) removal ability.

30 May 2023

Electronic Nose Consistently Detects VOCs at Low Concentrations

Volatile organic compounds are chemicals emitted as gases that can have adverse health effects. They are often found in paints, pharmaceuticals, and refrigerants, among other common products, but they can also act as markers of explosives, insect infestation, food spoilage, and disease.

30 May 2023

Game-Changing Research Shows Astrocytes as Key Regulators of Alzheimer's Disease Progression

Why do some people develop Alzheimer's disease while others don't? And, even more puzzlingly, why do many individuals whose brains are chock-full of toxic amyloid aggregates-;a telltale sign of Alzheimer's brain pathology-;never go on to develop Alzheimer's-associated dementias?

30 May 2023

Risk-Taking Behavior Increases After Unexpected Wins in Both Humans and Monkeys

How do humans make decisions when the outcomes are uncertain? One possible way would be to calculate the expected value of each option by multiplying each possible outcome amount by its probability and then choosing the option with the highest expected value.

29 May 2023