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Stickiness of influenza virus may determine the frequency of co-infection

Influenza viruses have an enormous impact in the U.S., with an estimated 25 million illnesses and 18,000 deaths in the 2022-23 flu season alone.

21 Mar 2023

INTEGRA Biosciences acquires Miroculus to accelerate genomics

INTEGRA Biosciences is delighted to announce that it has acquired Miroculus, a biotechnology specialist focused on developing hands-off automation solutions for next generation sequencing (NGS) protocols.

From INTEGRA Biosciences 20 Mar 2023

DNA drugs help restore the normal processing of protein-encoding RNA

A protein named TDP-43 has been lost from its normal location in the nucleus of the cell in virtually all persons having amyotrophic lateral sclerosis (ALS) and in up to half of all cases of frontotemporal dementia and Alzheimer’s disease (AD).

From UC San Diego 20 Mar 2023

Macrophages likely to be a potential target for ER+ breast cancer

Most immunotherapies that aim to increase T cell activity are ineffective in treating estrogen receptor-positive (ER+) breast cancer. A new study of invasive ER+ breast cancers led by researchers at the University of Pittsburgh School of Medicine implies that targeting a different type of immune cell called macrophages may be a more effective approach.

From University of Pittsburgh 20 Mar 2023

Perspectives on nucleolar DNA damage response in the fight against cancer

Cancer, which affects so many people each year, relies on proteins to proliferate throughout the body. Scientists are damaging the disease’s protein factories as part of a new tactic to combat the widespread disease.

20 Mar 2023

Genome editing proven effective to restore the vision of mice with genetic diseases

Chinese researchers have turned out to be successful in restoring the vision of mice with retinitis pigmentosa, which is considered to be one of the significant causes of blindness in humans.

20 Mar 2023

Novel mechanism by which bacteria colonize the gut identified

A new mechanism by which “good” bacteria colonize the gut was unraveled by scientists at Yale University. The finding could aid spur the development of new probiotic therapies.

20 Mar 2023

Novel gene to help breed climate resilient crops

For the first time, scientists have explained how a crucial gene in plants helps them use their energy more effectively, allowing them to produce more roots and absorb more water and nutrients.

20 Mar 2023

The protein synthesis mechanism in the Giardia parasite

Cryo-electron microscopy was employed by Uppsala University researchers to reveal information on the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhea. The new findings could help in the development of specific medicines to combat Giardia and other protozoan parasites.

20 Mar 2023

Amide-to-ester substitutions can enhance the membrane permeability of cyclic hexapeptides

Cyclic peptides often exhibit low membrane permeability which can be significantly improved via amide-to-ester substitutions-;as demonstrated by researchers from Tokyo Institute of Technology.

20 Mar 2023

Study discovers the ability of certain blood immune cells to proliferate

The ability of a cell to divide, to proliferate, is essential for life and gives rise to the formation of complex organisms from a single cell.

20 Mar 2023

Researchers uncover the role of third intracellular loop in GPCR's signaling mechanism

More than a third of FDA-approved drugs work by targeting a G protein-coupled receptor, or GPCR. The human body has more than 800 types of GPCRs that provide cells with information about the external environment to calibrate responses.

20 Mar 2023

Study presents top 100 research questions facing plant science

Without plants, we'd have no air to breathe or food to eat, yet plant science lingers in the shadowy wings while other fields take center stage.

20 Mar 2023

New antibody "cocktail" may help counter the Lassa virus

The finding, made with the use of the Advanced Photon Source, shows a new way to exploit monoclonal antibodies to subvert the "shield" of the virus, potentially paving the way for new therapies.

20 Mar 2023

Immune landscape in invasive ER+ breast cancers reveals a macrophage-driven microenvironment

Most immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer.

20 Mar 2023

Genomic study helps to better understand the origins, history of Tibetan and Sherpa ethnic groups

The Tibetan Plateau, the highest and largest plateau above sea level, is one of the harshest environments settled by humans.

20 Mar 2023

Study suggests new strategy for treating arrhythmogenic cardiomyopathy

University of Utah Health scientists have corrected abnormal heart rhythms in mice by restoring healthy levels of a protein that heart cells need to establish connections with one another.

20 Mar 2023

New combination therapy regimen may reduce prostate cancer progression or death by 37%

TALAPRO-2, a study led by Neeraj Agarwal, MD, FASCO, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progression or death by 37%.

20 Mar 2023

Cancer cells use new DNA repair mechanism to recover from next-generation cancer radiation therapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

20 Mar 2023

Delaying paralysis in ALS by using designer DNA drug

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.

20 Mar 2023

Research News and Research

Stickiness of influenza virus may determine the frequency of co-infection

INTEGRA Biosciences acquires Miroculus to accelerate genomics

DNA drugs help restore the normal processing of protein-encoding RNA

Macrophages likely to be a potential target for ER+ breast cancer

Perspectives on nucleolar DNA damage response in the fight against cancer

Genome editing proven effective to restore the vision of mice with genetic diseases

Novel mechanism by which bacteria colonize the gut identified

Novel gene to help breed climate resilient crops

The protein synthesis mechanism in the Giardia parasite

Amide-to-ester substitutions can enhance the membrane permeability of cyclic hexapeptides

Study discovers the ability of certain blood immune cells to proliferate

Researchers uncover the role of third intracellular loop in GPCR's signaling mechanism

Study presents top 100 research questions facing plant science

New antibody "cocktail" may help counter the Lassa virus

Immune landscape in invasive ER+ breast cancers reveals a macrophage-driven microenvironment

Genomic study helps to better understand the origins, history of Tibetan and Sherpa ethnic groups

Study suggests new strategy for treating arrhythmogenic cardiomyopathy

New combination therapy regimen may reduce prostate cancer progression or death by 37%

Cancer cells use new DNA repair mechanism to recover from next-generation cancer radiation therapy

Delaying paralysis in ALS by using designer DNA drug

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