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Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

In the late 1980s, scientists developed a revolutionary approach to treating acute myeloid leukemia (AML), a type of blood cancer. Called differentiation therapy, it amounted to a bona fide cure for many patients.

2 Dec 2021

Fungal network growth in grasses made possible by cell wall remodeling

Scientists now have a deeper understanding of how a fungus develops a symbiotic lifestyle inside grass leaf and why the grass leaf fails to defend itself against the intruder, thanks to research coming from Massey University in New Zealand and the University of Münster in Germany.

2 Dec 2021

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

2 Dec 2021

Study identifies genes that protect ovarian cancer from antitumor immunity

Immunotherapies are exhibiting better clinical benefit in the treatment of numerous cancers, particularly when used along with chemotherapy.

2 Dec 2021

Nanoparticles mimicking flu viruses to deliver large biological drug molecules

Nanoengineers from the University of California San Diego recently created a new and potentially efficient means to deliver messenger RNA (mRNA) into cells.

2 Dec 2021

Experts create new software that determines a person’s past infections

Recent research suggested that grouping of pathogen-recognizing proteins on immune T cells might be vital in pinpointing if an individual had an infection in the past.

2 Dec 2021

Novel technique precisely corrects DNA errors in cultured patient cells

Scientists recently created a technique to accurately and quickly correct genetic alterations in the cultivated patient cells.

2 Dec 2021

Scientists test the accuracy of enzymes that copy DNA under weightlessness

Researchers at Queen’s University boarded a modified Falcon 20 aircraft at Ottawa airport on May 22nd, 2019 as part of a scheduled “vomit comet” flight. In this mode of flight, the plane repeatedly climbs in a steep parabola to 8 km, alternating with a freefall descent.

2 Dec 2021

Cytomegalovirus accelerates the decline of the immune system regardless of age

Scientists from the University of Córdoba have been investigating the changes that occur in the T lymphocytes of the immune system with increasing age.

2 Dec 2021

Researchers find that the VCP/p97 protein unfolds, separates other protein structures

Thanks to an old needlework trick that a protein in the human body is aware of, rather than threading yarn into the eye from the end, it could be simpler to pass a loop through it.

2 Dec 2021

Researchers successfully generated Leydig cells from human iPS cells

Scientists recently succeeded in creating Leydig cells from human induced pluripotent stem (iPS) cells.

2 Dec 2021

Study finds amphipathic peptide that safely opens endosomal membrane

The cell plasma membrane and the derived endosomal membranes are both greasy barriers that prevent the inflow of water-soluble macromolecules like nucleic acids and proteins into cells.

2 Dec 2021

Study unearths novel mechanism coordinating the assembly of cell components

A group of researchers recently unearthed vital information on how gene expression is orchestrated.

2 Dec 2021

Study analyzes response of individuals from diverse populations to infections

A recent study has identified differences in immune pathway activation to influenza infection between people of European and African genetic ancestry.

2 Dec 2021

New study shows how neuroblastoma cells deal with rapid division

The cells of a certain tumor type, called neuroblastoma, divide very rapidly. This rapid division can have potentially fatal consequences for them. A new study shows how neuroblastoma cells deal with this dilemma.

1 Dec 2021

Lung cancer: Cholesterol metabolism of tumor-associated macrophages found to be severely compromised

Significant changes in lipid metabolism are known to occur in cells associated with non-small-cell lung carcinoma – the most common form of lung cancer.

1 Dec 2021

Custom Biofluid & Tissue Procurement Service

Global provider of human and animal biospecimens - AMSBIO offers a custom procurement service enabling researchers to source specific biofluid and tissue samples which are not already available in their extensive biorepository.

From AMS Biotechnology 1 Dec 2021

Researchers use X-ray from 3rd synchrotron facility to analyze 3D structure of chromosomes

Threads or earphone cables placed in tight spaces get easily tangled. On the contrary, our body's long and loose DNA packs into rod-shaped chromosomes one-millionth its size when the cell divides.

30 Nov 2021

Researchers show that tumor cells contribute differently to the formation of metastases

A type of cell transformation known as EMT enables cancer cells to break away from the tumor and form metastases elsewhere.

30 Nov 2021

Treatment with common allergy medication linked to improved immunotherapy response

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

29 Nov 2021

Cell News and Research

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

Fungal network growth in grasses made possible by cell wall remodeling

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

Study identifies genes that protect ovarian cancer from antitumor immunity

Nanoparticles mimicking flu viruses to deliver large biological drug molecules

Experts create new software that determines a person’s past infections

Novel technique precisely corrects DNA errors in cultured patient cells

Scientists test the accuracy of enzymes that copy DNA under weightlessness

Cytomegalovirus accelerates the decline of the immune system regardless of age

Researchers find that the VCP/p97 protein unfolds, separates other protein structures

Researchers successfully generated Leydig cells from human iPS cells

Study finds amphipathic peptide that safely opens endosomal membrane

Study unearths novel mechanism coordinating the assembly of cell components

Study analyzes response of individuals from diverse populations to infections

New study shows how neuroblastoma cells deal with rapid division

Lung cancer: Cholesterol metabolism of tumor-associated macrophages found to be severely compromised

Custom Biofluid & Tissue Procurement Service

Researchers use X-ray from 3rd synchrotron facility to analyze 3D structure of chromosomes

Researchers show that tumor cells contribute differently to the formation of metastases

Treatment with common allergy medication linked to improved immunotherapy response

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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