Cell Death News and Research

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CD276 Antibody Strategy Offers Hope For Immune-Resistant Lung Tumors

The study highlights 8H8_SDIE's role in activating NK cells against NSCLC, offering a new strategy for patients resistant to conventional immunotherapies.

6 Aug 2025

Discovery of New Mitophagy Trigger Offers Hope for Parkinson’s Disease

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest study, leading cell biologists at the Max Perutz Labs at the University of Vienna investigated mitophagy – a form of autophagy – and came to a remarkable conclusion: the researchers have described a new trigger for mitophagy.

29 Jul 2025

Misfolded Proteins in Mitochondria Linked to Type 2 Diabetes

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding.

23 Jul 2025

MiROM Uses Infrared Light to Detect Protein Changes in Single Cells

MiROM identifies proteins by using mid-infrared light to detect molecular vibrations – essentially the natural "dance" of molecules within protein structures.

16 Jul 2025

Small Genetic Change in Humans Weakens Immune Attack on Solid Tumors

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates.

4 Jul 2025

Fusion Genes Emerge as Key Drivers in Cancer Development

Fusion genes, arising from abnormal chromosomal rearrangements, are gaining recognition as pivotal players in cancer development. These genetic alterations result in the creation of hybrid genes with altered functions, often driving tumor progression.

25 Jun 2025

Frog Egg Extracts Illuminate the Untangling Mechanism of DNA Knots

Research reveals how G-quadruplex DNA structures are untangled, highlighting a role for RNA in genome stability and potential cancer therapy strategies.

13 Jun 2025

Base Editing Breakthrough Brings Hope for Genetic Disease Treatment

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation.

5 Jun 2025

Exploring the Metabolic Pathways of Cancer Cells

Research from the University of Cincinnati reveals how the MYC oncogene alters PRPS enzymes, impacting redox homeostasis and lymphoma progression.

30 May 2025

Natural Deep Eutectic Solvents Enhance Yield and Antibacterial Activity of Zanthoxylum bungeanum

NADES treatments significantly boost essential oil yield and antibacterial activity in Zanthoxylum bungeanum, offering a natural solution to food contamination.

23 May 2025

Compression Drives Aggressive Behavior in Liver Cancer Cells

Yale researchers are providing new insights into how physical forces, such as cells being compressed in physically restrictive environments, play key roles in cancer progression.

21 May 2025

Novel Molecule Inducing Ferroptosis for Metastatic Cancer Therapy

Scientists from Institut Curie, the CNRS, and Inserm have just created a novel class of molecules capable of destroying cancer cells that are resistant to current treatments and cause recurrence.

8 May 2025

Key Regulators of Mutant Huntingtin Protein in Neuronal Transport

Ten years ago, researchers from the University at Buffalo provided some insight into a long-standing neuroscience conundrum: How precisely does Huntington's disease result from a mutation in the huntingtin protein (HTT)?

6 May 2025

Lipid Peroxidation in Lysosomes Unleashes Ferroptosis in Tumors

The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death.

2 May 2025

The Future of Chicken? Scientists Grow Whole Cuts in a Bioreactor

This research introduces a hollow fiber bioreactor for cultured chicken meat, optimizing tissue engineering with enhanced perfusion and structural integrity.

25 Apr 2025

Researchers Create DNA Editing Technique to Improve Lactobacillus Strains

A Kobe University team was able to edit the DNA of Lactobacillus strains directly without a template from other organisms.

24 Apr 2025

New Protein Identified as Regulator of Mitochondrial Calcium Transport

Calcium transport into and out of mitochondria – the powerhouses of cells – is central to cellular energy production and cell death.

9 Apr 2025

QRICH1 Protein Found to Control T Cell Activation in Cancer and Autoimmune Diseases

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025

Wheat's Pathogen Defense Strengthened by Tandem Kinase Proteins

Wheat is grown over more land area than any other food crop. Among pathogen-driven threats to wheat, fungi top the list, causing billions of dollars of losses each year and posing a serious challenge to food security worldwide.

3 Apr 2025

ER-Stressed Fat Cells Influence Liver Function Through Lipid Signaling

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions-as enzymes, transporters, hormones, antibodies, receptors, and more.

2 Apr 2025