Cell Death News and Research

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Migrating Neurons Break and Repair Their Own DNA During Brain Cortex Formation

Newborn nerve cells must squeeze through crowded, narrow spaces-through dense tissue, past other cells, between fibers-to reach the areas where they form neural circuits in the brain cortex.

18 Jun 2026

Scientists Discover Genetic Root of Rare Childhood Inflammatory Skin Disorder

An international team of researchers has identified a genetic cause for a rare inflammatory skin condition.

15 Jun 2026

Study Shows Protein Fragment Reduces Neuronal Degeneration in Mice

Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have discovered a new strategy that may protect neurons and other brain cells involved in Parkinson's disease in the future.

13 Jun 2026

New Protein Storage Condensates May Hold Clues for Better Anticancer Strategies

A team of Johns Hopkins Bloomberg School of Public Health researchers has discovered large droplets of proteins known as condensates near inactive chromosome regions within the cell nucleus that are a feature of some cancer cells and may hold clues for better anticancer strategies.

12 Jun 2026

New Cell Therapy Modifies Natural Killer Cells Against Cancer

Scientists have made great progress in harnessing the body's own immune cells to treat so-called liquid tumors, cancers of the blood and lymphatic system.

11 Jun 2026

Researchers Outline Dynamic Protein Control Systems for Better Clinical Decisions

Cancer has often been explained through mutations in deoxyribonucleic acid (DNA) or changes in ribonucleic acid (RNA), but these layers do not fully explain why tumors with similar genetic profiles can behave differently.

10 Jun 2026

Coffee Can Now Serve as a Biological Switch for Medicines

For many of us, a warm cup of coffee is how we start our day. For Texas A&M Health researchers, it may also offer a new way to control engineered cells in future medicines.

9 Jun 2026

Scientists Identify EHMT2 Enzyme as Main Cause of 5-FU Failure

One of the most widely used chemotherapeutic agents for colorectal cancer is 5-fluorouracil (5-FU), a cornerstone treatment that has improved outcomes for countless patients.

9 Jun 2026

Live-Imaging Techniques Reveal How Stem Cells Collectively Suppress Tumors

It all starts with a single cell.

2 Jun 2026

Scientists Discover a Metabolic Switch That Regulates Ferroptosis

The loss of an enzyme can reprogram cellular metabolism in a way that protects cells from a specific form of cell death. Paradoxically, the presumed blockade of this enzyme has the opposite effect.

1 Jun 2026

Ovarian Cancer Fluid Helps Tumors Evade Cell Death

Ascites in ovarian cancer rewires tumor metabolism, protecting cells from ferroptosis and promoting metastasis, revealing potential therapeutic targets.

27 May 2026

Study Identifies Potential Metabolic Biomarkers for Metastatic Castration-Resistant Tumors

Ceramides-lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death-and their metabolites have been implicated in the development of cancer and other conditions.

26 May 2026

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells.

22 May 2026

Polymer Platforms Help Focus Immune Attack on Cancerous Tumors

Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.

21 May 2026

Disrupted Honeycomb Cellular Patterns in the Early Brain May Drive Cancer and Birth Defects

University of Virginia School of Medicine scientists have revealed how mistakes in the final step of cell division can have dire consequences for developing brain cells. The findings offer important new insights into cancer and developmental disorders, helping explain how the body tries to protect itself and what happens when it can't.

21 May 2026

New 3D Human Liver Model Mimics Chronic Disease For 30 Days

Researchers developed a 3D liver model that functions for a month, replicating inflammation and fibrosis, crucial for studying liver diseases and therapies.

19 May 2026

Animals Adapt Rapidly Through Protein Networks, Not Genes

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.

15 May 2026

Interactions Across the Genome Drive Neurodevelopmental Risks

People who have the same deletion of a section of chromosome 16 are susceptible to neurodevelopmental disorders; however, some may simply show moderate psychological symptoms like anxiety or depression, while others may have significant intellectual disability or developmental delay.

6 May 2026

Long Read Sequencing Uncovers Telomere Length Variation Across Chromosomes

In a new proof-of-concept study published in Nature Communications, researchers at the University of Chicago analyzed genomic data from more than 2,500 participants in the national All of Us research program to estimate chromosome-specific telomere length (csTL).

30 Apr 2026

How the Microbiome Shapes Cancer Immunity and Therapy Response

This review examines how the human microbiome regulates anti-tumor immunity through DNA damage, inflammation, immune-cell activity, microbial metabolites, and tumor microenvironment remodeling. It highlights emerging microbiome-based strategies, including FMT, probiotics, prebiotics, engineered bacteria, and live biotherapeutics, while stressing the need for rigorous validation and clinical trials.

29 Apr 2026