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Researchers Develop Method to Visualize Nanocarriers at Single-Cell Level

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical University Munich (TUM) have taken an important step to answer this question.

16 Jan 2025

Breakthrough in Nanopore Technology Could Transform Disease Detection

UC Riverside scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules.

3 Jan 2025

New Treatment Targets Tumor Microenvironment to Fight Breast Cancer

"Build your enemy a golden bridge to retreat across" is a piece of advice offered by Sun Tzu in his ancient military treatise, The Art of War. It turns out that cancerous growths adopt this strategy in their battle against the immune system.

24 Dec 2024

Advancements in Cell-Penetrating Antibodies Open New Avenues in Cancer Therapy

A news feature on the research paper "Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition" by Rackear et al. was published in Oncotarget's Volume 15 on November 22, 2024, titled "Advancements in cell-penetrating monoclonal antibody treatment."

12 Dec 2024

CRISPR Reveals Hidden Functions of Noncoding RNA

Genes contain instructions for protein production, with the central dogma of biology stating that this information flows from DNA to RNA to proteins.

8 Nov 2024

UAB Develops a Polygenic Score to Predict Cancer Drug Resistance

In 1937, President Franklin Roosevelt signed the National Cancer Act, launching a nationwide effort to combat the disease.

8 Nov 2024

Bipolar Disorder and Epilepsy Share Genetic Roots

A team of researchers from the Chinese Academy of Sciences has uncovered compelling evidence of a genetic link between bipolar disorder type I (BD-I) and epilepsy, potentially revolutionizing our understanding of these complex neuropsychiatric conditions.

1 Oct 2024

A Novel Genetic Inference Method for Detecting Rare Disease Variants

Undiagnosed cases of Long QT syndrome have been found, thanks to an inventive examination of shared genomic sequences, which is a sign of distant “relatedness” and can cause irregular heart rhythms, fainting, and sudden cardiac death.

30 Sep 2024

New AI Tool Revolutionizes Prediction of Rare Genetic Variant Effects

Whether we are predisposed to particular diseases depends to a large extent on the countless variants in our genome.

26 Sep 2024

Researchers Uncover Method to Boost Stem Cell Production Using Interferon Gamma

Researchers at the Centre for Genomic Regulation (CRG) have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice.

8 Aug 2024

Specific Genes May Determine Stroke Recovery Path

New research led by UCLA Health has found that specific genes may be related to the trajectory of recovery for stroke survivors, providing doctors insights useful for developing targeted therapies.

29 Jul 2024

Global Gene Expression Data Improves Precision in Genetics

The majority of human genetics research has traditionally concentrated on individuals with European ancestry, a long-standing bias that may reduce the precision of scientific predictions for individuals from other populations.

18 Jul 2024

Are Advances in AI Technology Transforming Immunohistochemistry Analysis in Pathology?

The platforms and AI-based programs that are being used to analyze immunohistochemical markers and interpret the results.

3 Jul 2024

Enhancing Precision and Versatility in Genetic Sensor Design

Genetic sensors play a crucial role within organisms by regulating gene expression in response to environmental stimuli.

2 Jul 2024

Leica Microsystems' Aivia 14 Enhances 3D Multiplexed Image Analysis

Leica Microsystems, a leading provider of microscopy and scientific instrumentation, has released version 14 of Aivia, its flagship image analysis solution.

22 Jun 2024

MIT Researchers Develop Amber-Like Polymer for Room-Temperature DNA Storage

In the movie "Jurassic Park," scientists extracted DNA that had been preserved in amber for millions of years, and used it to create a population of long-extinct dinosaurs.

14 Jun 2024

AI Uncovers Rare Mutations with Major Impact on Heart Health

Researchers at the Icahn School of Medicine at Mount Sinai have discovered unusual coding variants in 17 genes that provide insight into the molecular causes of coronary artery disease (CAD), the world's leading cause of morbidity and mortality.

12 Jun 2024

AMPLON Simplifies DNA Amplification for Diverse Medical Applications

A team of researchers from Case Western Reserve University School of Medicine has created a novel method for target DNA sequence amplification, testing, and analysis.

6 Jun 2024