Protein Engineering News and Research

RSS

New AI-Assisted Methods to Discover Novel Deaminase Proteins with Unique Functions

At the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, GAO Caixia’s group has introduced the use of artificial intelligence (AI)-assisted techniques to find out novel deaminase proteins with special functions via structural prediction and classification.

28 Jun 2023

Novel 3D Structure can Serve as Blueprint to Engineer New BoNT/E Variants

A team of researchers from the University of California, Irvine, have revealed the first crystal structures of the receptor-binding domain of botulinum neurotoxin E (BoNT/E) in complex with its human neuronal receptors, synaptic vesicle glycoprotein 2A (SV2A).

28 Apr 2023

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have harnessed a natural bacterial system to develop a new protein delivery approach that works in human cells and animals.

30 Mar 2023

AI develops first-ever functional artificial protein

Scientists have developed an AI system that can produce artificial enzymes from scratch. Even though several of these enzymes’ artificially generated amino acid sequences differed noticeably from those of any known natural protein, they nonetheless performed as well in laboratory testing as those found in nature.

27 Jan 2023

Potential to rectify various disease-causing mutations enhanced by CRISPR-based enzymes

Designing genome editing strategies for each patient’s mutation would be impractical and expensive because many genetic diseases are induced by diverse mutations spread across an entire gene.

18 Jan 2023

Small fluorescent protein helps researchers to capture deeper, more precise biomedical images

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

7 Dec 2022

Preventing protein-protein interactions with a new tool

Proteins constantly interact with one another inside cells to perform various tasks. Blocking the binding of two or more proteins appears as a potential treatment for some diseases where these functions are altered.

1 Dec 2022

Researchers introduce CRISPR to enable gene editing in cockroaches

According to a study released by Cell Press on May 16th, 2022, in the journal Cell Reports Methods, scientists have created a CRISPR-Cas9 technique to facilitate gene editing in cockroaches.

23 May 2022

Researchers discover a unique technique to fight hospital-borne disease

A study team developed an early-stage therapy that sabotages the pump and restores antibiotic efficiency by disclosing the structure of a protein needed by bacteria to pump out antibiotics.

From New York University (NYU) 4 Apr 2022

Evonetix granted patent for technology enabling thermally-controlled DNA synthesis

EVONETIX LTD (‘Evonetix’), the synthetic biology company bringing semiconductor technology to DNA synthesis, today announced it has been granted patent EP3551331B1 in Europe for its proprietary thermal control technology for DNA synthesis, as well as the design and manufacture of its silicon chips.

From Evonetix 4 Apr 2022

Using E.Coli to bring 3D Printing to Life

In this interview, we speak to Dr. Avinash Manjula Basavanna about his latest research that incorporated E. Coli to bring 3D printing materials to life.

From Massachusetts Institute of Technology (MIT) 13 Jan 2022

New CRISPR technology could improve diagnostic tests for COVID-19

A new type of CRISPR platform that leverages the benefits of a compact RNA-editing protein could result in enhanced diagnostic tests for COVID-19.

2 Dec 2021

New technology harnesses a natural feature of therapeutic antibodies to attack blood cancer cells

Researchers at the University of Southampton and biopharma company UCB have found a way to enhance the natural ability of therapeutic antibodies to attack blood cancer cells using part of the human immune system known as the complement cascade, opening the way for a potential new class of treatments.

8 Sep 2021

Protein Engineering News and Research

New AI-Assisted Methods to Discover Novel Deaminase Proteins with Unique Functions

Novel 3D Structure can Serve as Blueprint to Engineer New BoNT/E Variants

Harnessing a natural bacterial system to deliver proteins in mice and human cells

AI develops first-ever functional artificial protein

Potential to rectify various disease-causing mutations enhanced by CRISPR-based enzymes

Small fluorescent protein helps researchers to capture deeper, more precise biomedical images

Preventing protein-protein interactions with a new tool

Researchers introduce CRISPR to enable gene editing in cockroaches

Researchers discover a unique technique to fight hospital-borne disease

Evonetix granted patent for technology enabling thermally-controlled DNA synthesis

Using E.Coli to bring 3D Printing to Life

New CRISPR technology could improve diagnostic tests for COVID-19

New technology harnesses a natural feature of therapeutic antibodies to attack blood cancer cells

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

New AI-based method can lead to faster, low-cost development of protein-based drugs

New class of protein materials can influence cell signaling

Controlling biological functions of DNA with the aid of light

“Lab-made” proteins have better industrial applicability than natural proteins

Scientists identify potential targets against coronavirus

Researchers create an algorithm that predicts allosteric sites in proteins

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics