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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

m-RNA and Immunostimulant Activate CAR-Macrophages in Cancer Cells to Fight Cancer

Immune cells (macrophages) capable of combating cancer exist within tumors in the human body, but they are unable to fulfill their functions adequately due to tumor suppression.

2 Jan 2026

Interferon Response in Female Brains Linked to Alzheimer's Progression

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester has long been studying this disease and is looking more closely at the differences between male and female brains.

30 Dec 2025

New ddHodge Method Reconstructs Cell Fate Dynamics with High Accuracy

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics of how cells decide their fate. As reported in Nature Communications, this approach paves the way for a deeper understanding of the biological processes involved in development, regeneration, and disease.

30 Dec 2025

Calcium Signaling Suppresses Lignin Accumulation in Pear Stone Cells

Stone cells arise from lignified secondary cell walls and cause a gritty texture, reduced sweetness, and poor flavor in many pear cultivars.

23 Dec 2025

Researchers Uncover Gene Control Elements Tied to Alzheimer’s Disease

When most of us think of DNA, we have a vague idea it's made up of genes that give us our physical features, our behavioral quirks, and keep our cells and organs running.

19 Dec 2025

Long Non-Coding RNA Found to Directly Control Cell Size

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases.

18 Dec 2025

A Molecular Tug-of-War Shapes Gene Regulation and Disease

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders - including cancers, neurodegenerative diseases and immune disorders - originate, as well as how to potentially treat them, according to researchers at Penn State.

18 Dec 2025

Cell Wall Stiffness Directs Plant Stem Cell Fate

Imagine if our bodies could grow new organs throughout our entire lives. Plants do this constantly, thanks to the tiny, powerful reservoirs of stem cells. But how do these cells know when to divide, and how do they ensure each division is perfectly oriented to build a leaf, a stem, or a flower?

18 Dec 2025

RNAConnect Launches the UltraMarathonRT Direct RNA‑Seq Kit to Advance Nanopore-Based Native RNA Sequencing

RNAConnect, a life science company providing next generation tools to the RNA community, today announced the commercial availability of the UltraMarathonRT® Direct RNA‑Seq (uMRT DRS) Kit, a native‑RNA library preparation solution for Oxford Nanopore Technologies® direct RNA sequencing (SQK-RNA004).

From RNAConnect 17 Dec 2025

CRISPR Reveals Dark Genome Regions That Sense Cellular Mechanics

Researchers at Duke University used CRISPR technologies to discover previously unannotated stretches of DNA in the 'dark genome' that are responsible for controlling how cells sense and respond to the mechanical properties of their local environment.

12 Dec 2025

New Insights Into LARP6-RNA Binding Could Lead to Fibrosis Therapies

A research team at the Institute of Molecular Biophysics and the Department of Chemistry and Biochemistry at Florida State University has made a significant discovery regarding the interaction between a protein present in the human body and RNA, which may pave the way for innovative treatments for tissue scarring, commonly referred to as fibrosis.

12 Dec 2025

Mitochondrial Supercomplex Protein COX7RP Extends Lifespan and Healthspan

As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health.

11 Dec 2025

Breaking the Interspecies Immune Barrier to Advance Human Organ Generation

Failure of human pluripotent stem cells (PSCs) to survive when grown with the PSCs of distantly related species occurs because of an innate immune reaction in the nonhuman cells, a study led by UT Southwestern Medical Center researchers suggests.

9 Dec 2025

How Tumor Stem Cells Hijack Neutrophils to Evade Immunotherapy

Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors.

9 Dec 2025

Syntax Bio Develops CRISPR Technology to Program Stem Cell Gene Activity

Syntax Bio, a synthetic biology company programming the next generation of cell therapies, today announced the publication of new research in Science Advances detailing the company's CRISPR-based Cellgorithm™ technology, which lays the groundwork for programmable control of gene activity in human stem cells and offers an alternative to the slow, variable manual processes researchers use today.

8 Dec 2025

Broken DNA Loops Trigger Lymphoma Development

Cancer involves more than just genetic mutations; it also involves structural failures. Consider a city where roads disappear, isolating communities from vital resources.

8 Dec 2025

PLAMseq Revolutionizes Simultaneous Analysis of Genome Proteins and Their Locations

A team from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) has developed an innovative technique called PLAMseq (proximity-labelled affinity-purified mass spectrometry plus sequencing) that, for the first time, allows simultaneous analysis of chromatin-associated proteins and their location in the genome in a single experiment.

5 Dec 2025

Cells Use Condensates to Save RNA Messages During Stress

All cells need to sense and respond to their environment, to know when to activate genes, build proteins, and carry out their basic functions.

4 Dec 2025

New Tool Predicts Which Intrinsically Disordered Regions Drive Condensate Formation

Fusion oncoproteins arise when a gene fuses with another gene and acquires new abilities. Such abilities can include the formation of biomolecular condensates, "droplets" of concentrated proteins, DNA or RNA.

4 Dec 2025

Circular Single-Stranded DNA Molecule Can Simultaneously Silence Multiple MicroRNAs

Professor Dongsheng Liu of Tsinghua University, Professor Ziyang Hao of Capital Medical University, and Researcher Yuanchen Dong of the Institute of Chemistry, Chinese Academy of Sciences, have collaborated to develop a circular single-stranded DNA molecule capable of simultaneously silencing multiple miRNAs.

4 Dec 2025