Receptor News and Research

RSS

New Research Explains How Alcohol Inhibits Gut Health

Alcohol-associated liver disease (ALD) is a leading cause of liver transplantation and mortality globally, and its effect is only increasing.

27 Aug 2025

New Research on Amylin Could Pave the Way for Next-Generation Obesity Drugs

Amylin, a hormone that regulates both appetite and blood sugar by activating three distinct brain receptors, might serve as the foundation for the next generation of obesity drugs.

20 Aug 2025

Missing Microexons Disrupt Synapse-Related Proteins in Pediatric Glioma

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

19 Aug 2025

Automated 15-minute, Aseptic Micro-Sampling of T Cells

Auto-CeSS is an automated system for aseptic 30 μL sample collection, enhancing process monitoring and reducing contamination in cell therapy manufacturing.

13 Aug 2025

Parkinson’s Gene Mutation Blocks Vital Neuroprotective Signals

GBA1 mutations impair ciliary Hedgehog signaling in Parkinson's disease, reducing neuroprotective factors and highlighting a shared pathogenic pathway.

7 Aug 2025

CD276 Antibody Strategy Offers Hope For Immune-Resistant Lung Tumors

The study highlights 8H8_SDIE's role in activating NK cells against NSCLC, offering a new strategy for patients resistant to conventional immunotherapies.

6 Aug 2025

Scientists Uncover New Activation Mechanism of the Human Sweet Taste Receptor

Sweet taste receptors are proteins in taste buds that detect sugar and other sweeteners, but the mechanism underlying how they elicit a sweet response has been unclear.

5 Aug 2025

AI-Powered Protein Design Opens Doors to New T-Cell Based Immunotherapies

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in T-cell development and function.

4 Aug 2025

Thalamus Found to Modulate Cortical Sensitivity to Touch

The cerebral cortex processes sensory information via a complex network of neural connections. How are these signals modulated to refine perception? A team from the University of Geneva (UNIGE) has identified a mechanism by which certain thalamic projections target neurons and modify their excitability.

31 Jul 2025

Discovery of New Mitophagy Trigger Offers Hope for Parkinson’s Disease

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest study, leading cell biologists at the Max Perutz Labs at the University of Vienna investigated mitophagy – a form of autophagy – and came to a remarkable conclusion: the researchers have described a new trigger for mitophagy.

29 Jul 2025

AI-Driven Precision for Next-Gen Cancer Immunotherapy

Consider how immune cells may be tailored to combat any type of cancer. T cell receptor (TCR) therapy has the potential to become the standard cancer treatment.

29 Jul 2025

Amino Acids Guide Cell Responses to Drugs Through a Complex Network

Amino acids play a fundamental role in regulating how cells respond to drugs. These molecules, which form proteins, act like bricks that communicate with each other within a structure.

17 Jul 2025

Hormone-Sensitive Brain Circuit Drives Mating Behaviors in Mice

In animals with social structures, the drive to reproduce is a complex process; governed by the brain, it's influenced by both internal cues such as hormones and external factors such as interactions with potential mates.

17 Jul 2025

UAB Identifies Six Novel Subsets, Reshaping Immune Knowledge

The study highlights T-bet's importance in memory B cells, essential for rapid antibody production and sustained immune defense against influenza.

14 Jul 2025

Microglia Replacement Halts Progression of Fatal Neurological Disease in Mice and Humans

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an average age of onset of 43 years and an average life expectancy of only 3 to 5 years after symptoms begin.

11 Jul 2025

Vanderbilt and Parse Biosciences Join Forces to Accelerate Measles Antibody Discovery

Vanderbilt University Medical Center and Parse Biosciences, an innovator in single-cell sequencing, are collaborating on a new treatment to help unvaccinated measles victims, as the U.S. measles outbreak has now reached its highest case count in 30 years.

9 Jul 2025

New Cellular Signature Reveals Why Some Prostate Cancers Resist Standard Treatment

A new study from University of Michigan Rogel Cancer Center researchers identifies a cellular signature that explains why about one-third of prostate cancers respond especially poorly to treatment.

9 Jul 2025

Engineered Macrophages Enable CAR T Cells to Overcome Glioblastoma Barriers

A team of researchers from the San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET, Milan), led by Nadia Coltella and Luigi Naldini, has unveiled a powerful strategy to rejuvenate the effectiveness of chimeric antigen receptor (CAR) T cell therapy against glioblastoma, one of the most lethal and treatment-resistant brain tumors.

4 Jul 2025

Study Links Cell Surface Receptor Pairing to Proper Embryonic Body Shape

During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo.

4 Jul 2025

Uncovering the Gut Virome's Role in Health and Disease

The human gut is home to trillions of microbes, yet scientific understanding has largely focused on bacteria, leaving the virome—the community of viruses—relatively uncharted.

4 Jul 2025