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Glass surface embedded with self-assembled gold nanoparticles can improve live-cell imaging

In the quest to image exceedingly small structures and phenomenon with higher precision, scientists have been pushing the limits of optical microscope resolution, but these advances often come with increased complication and cost.

9 Nov 2020

White blood cells can be trained to attack tumor cells

Scientists at the National Center for Tumor Diseases Dresden (NCT/UCC) and Dresden University Medicine, together with an international team of researchers, were able to demonstrate that certain white blood cells, so-called neutrophil granulocytes, can potentially - after completing a special training program - be utilized for the treatment of tumors.

9 Nov 2020

Genetically edited form of herpes simplex virus outperforms key vaccine candidate

A genetically edited form of a herpes simplex virus -- rewired to keep it from taking refuge in the nervous system and eluding an immune response -- has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln.

9 Nov 2020

New method to improve preclinical evaluation of CAR-T cell therapies

Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies.

9 Nov 2020

Researchers show how encapsulated viruses hijack biosynthetic pathways in cells

Researchers from the Universities of Melbourne, York, Warwick and Oxford have shed light on how encapsulated viruses like hepatitis B, dengue and SARS-CoV-2 hijack the protein manufacturing and distribution pathways in the cell - they have also identified a potential broad spectrum anti-viral drug target to stop them in their tracks.

9 Nov 2020

Unrelated mutations can lead to false positive results in men with advanced prostate cancer

Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies.

6 Nov 2020

Study provides key insight to better understand the development of Type 2 diabetes

Scientists have found that insulin has met an evolutionary cul-de-sac, limiting its ability to adapt to obesity and thereby rendering most people vulnerable to Type 2 diabetes.

6 Nov 2020

Study shows how coronavirus block cells’ ability to produce protective proteins

One of the novel coronavirus' most insidious tricks is that it can block the ability of cells to produce protective proteins without hindering its own ability to replicate.

6 Nov 2020

Some crops are not adapted to gain from elevated CO2 levels

The U.S. backs out of the Paris climate agreement even as carbon dioxide (CO2) levels continue to rise. Through photosynthesis, plants are able to turn CO2 into yield. Logic tells us that more CO2 should boost crop production, but a new review from the University of Illinois shows that some crops, including corn, are adapted to a pre-industrial environment and cannot distribute their resources effectively to take advantage of extra CO2.

6 Nov 2020

A stepwise approach to increase crop yield

GAIN4CROPS is developing novel disruptive technologies to overcome one of the main constraints of photosynthesis: the photorespiration, a process that reduces CO2 assimilation efficiency, and thus biomass yield and agricultural productivity.

6 Nov 2020

Epigenetic clock predicts the future growth of cancer cells

A team of researchers from IDIBAPS-Hospital Clínic and the University of Barcelona has headed an international study to design an epigenetic clock that can track the amount of cancer cells that have multiplied previously.

5 Nov 2020

Researchers create “developmental atlas” to classify the neurons of fruit flies

Using machine learning and gene sequencing, scientists from New York University have designed a “developmental atlas” of gene expression in neurons to classify over 250,000 neurons in the brains of fruit flies.

5 Nov 2020

Study sheds new light on key protein implicated in tumor development

A study headed by the University of Colorado Boulder has revealed a specific protein that is crucial for regulating the growth, proliferation, and function of cells, and how these cells were long implicated in the development of tumors.

5 Nov 2020

Study examines how extremophilic microbes can tolerate drastic space conditions

Since the dawn of space exploration, humankind has been fascinated by survival of terrestrial life in outer space. Outer space is a hostile environment for any form of life, but some extraordinarily resistant microorganisms can survive.

5 Nov 2020

Researchers reveal identity of the last unknown protein of autophagy

Drs. Nobuo Noda (Director) and Kazuaki Matoba (Senior Researcher) et al. at the Institute of Microbial Chemistry (BIKAKEN, Tokyo, Japan) discovered that Atg9, one of the proteins that function to mediate autophagy, has phospholipid-translocation activity (the lipid scramblase activity) between the two layers of the lipid bilayer and elucidated that the protein's activity brings about autophagosome membrane expansion.

5 Nov 2020

Researchers discover how tomato plants identify Cuscuta as a parasite

Working together with researchers from the University of Tübingen, the University of Tromsø, the UC Davis and the Sainsbury Laboratory in Norwich, biologists from Friedrich-Alexander Universität Erlangen-Nürnberg (FAU) have discovered how tomato plants identify Cuscuta as a parasite.

5 Nov 2020

Teratomas could provide a new glance at human development

Finding just the right model to study human development--from the early embryonic stage onward--has been a challenge for scientists over the last decade.

From UC San Diego 5 Nov 2020

Researchers identify a new solution for treating ligament injuries

Ligament injuries that affect scores of regular citizens and athletes are sidelined every year. Added to this, recovery is painful and takes a long time and, at times, a return to normal function is never achieved because of the formation of scars—an aspect that makes ligament injuries inclined to more damage.

4 Nov 2020

New report covers challenges and opportunities in gene therapies

Gene therapies are being approved for use in Canada but could strain healthcare budgets and exacerbate existing treatment inequities across the country.

4 Nov 2020