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Unveiling the Epigenetic Landscape of Blood Cancers

In recent years, biomedical laboratory research has undergone tremendous change, to the extent that computers have frequently replaced test tubes.

27 Nov 2024

Single-Cell Analysis Sheds Light on Leukemia Cell Heterogeneity

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM and the European Molecular Biology Laboratory (EMBL) used state-of-the-art single-cell analysis methods to analyze the cellular heterogeneity of a specific form of acute myeloid leukemia.

26 Nov 2024

New Imaging Method Unlocks Secrets of RNA Folding Dynamics

In a groundbreaking development, researchers from the United States and Denmark have successfully captured 3D images of individual RNA nanoparticles in the midst of their folding process.

26 Nov 2024

Dopamine and Serotonin Act as Opposing Forces in Learning and Reward

If you've heard of two of the brain's chemical neurotransmitters, it's probably dopamine and serotonin. Never mind that glutamate and GABA do most of the work -; it's the thrill of dopamine as the "pleasure chemical" and serotonin as tender mood-stabilizer that attract all the headlines.

26 Nov 2024

Locus Coeruleus Identified as Crucial for Maintaining Sleep Cycles

Researchers at the University of Lausanne have identified a novel role for the brain's 'locus coeruleus' in sleep and its disruptions.

26 Nov 2024

New Method for Understanding Brain Function and Dysfunction

An international group of researchers from FutureNeuro, the Research Ireland Centre for Translational Brain Science, and RCSI University of Medicine and Health Sciences have created a novel technique to characterize gene activity in the living human brain.

26 Nov 2024

New Role for the Golgi Apparatus in Cancer Immunotherapy

The Golgi apparatus modifies, sorts, and packages proteins to be sent to their final destinations, whether that is within or outside of the cell.

25 Nov 2024

Simplified Model Predicts Neuronal Activity in Zebrafish Gaze Control

Working with week-old zebrafish larva, researchers at Weill Cornell Medicine and colleagues decoded how the connections formed by a network of neurons in the brainstem guide the fishes' gaze.

25 Nov 2024

Deep Neural Connections Drive Social Thought, Study Says

We've all been there. Moments after leaving a party, your brain is suddenly filled with intrusive thoughts about what others were thinking. "Did they think I talked too much?" "Did my joke offend them?" "Were they having a good time?"

24 Nov 2024

Researchers Decode Complete Genome of Medicinal Plant Forsythia Suspensa

A recent study has decoded the complete genome of Forsythia suspensa, a plant renowned for its medicinal value and decorative appeal.

23 Nov 2024

Scientists Identify Gene Variant Linked to Early Miscarriages in Women

In what could be a major advance in understanding the genetic causes underlying human infertility, scientists led by researchers from Rutgers University-New Brunswick have identified a gene variant directly tied to early miscarriages in women.

23 Nov 2024

Human Cell Atlas Consortium Makes Major Progress in Understanding the Human Body

Researchers with the global Human Cell Atlas (HCA) consortium report significant progress in their quest for a better understanding of the cells of the human body in health and disease, with the publication today (20 November) of a Collection of more than 40 peer-reviewed papers in Nature and other Nature Portfolio journals.

22 Nov 2024

Mapping of Mouse Intestine Sheds Light on Immune Control and Adaptability

The intestine maintains a delicate balance in the body, absorbing nutrients and water while maintaining a healthy relationship with the gut microbiome, but this equilibrium is disrupted in parts of the intestine in conditions such as celiac disease, ulcerative colitis, and Crohn's disease.

22 Nov 2024

Discovery of Large Tandem Duplications Opens New Avenues for Cancer Treatment

Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic change known as large tandem duplications (TDs) that can arise from the collision of two critical cellular processes: transcription and DNA replication.

21 Nov 2024

Molecule Found to Aid Intestinal Healing and Prevent Tumor Growth in Colorectal Cancer

Researchers at Karolinska Institutet have found a molecule that can both help the intestines to heal after damage and suppress tumor growth in colorectal cancer.

21 Nov 2024

Brain Connectivity Surges at Birth, Study Reveals

Brain-imaging data collected from fetuses and infants has revealed a rapid surge in functional connectivity between brain regions on a global scale at birth, possibly reflecting neural processes that support the brain's ability to adapt to the external world, according to a study published November 19th, in the open-access journal PLOS Biology led by Lanxin Ji and Moriah Thomason from the New York University School of Medicine, USA.

20 Nov 2024