Tumor News and Research

RSS

Deciphering the Tumor Microenvironment with Spatial Transcriptomics

Spatial transcriptomics (ST) has emerged as a crucial technique for mapping gene expression across tissue sections while preserving vital locational data, setting it apart from traditional methods like bulk or single-cell RNA sequencing.

30 Nov 2023

Unraveling Stem Cell Destiny in Intestinal Organoids

Stem cells possess the remarkable ability to differentiate and replace deceased or impaired cells within the body.

27 Nov 2023

Nutrient Derived From Meat and Dairy Enhances Cancer Killing Ability of Immune Cells

Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to a new study by researchers from the University of Chicago.

27 Nov 2023

Engineering Stem Cells to Evade Immune Rejection

Cell and organ transplants have the potential to save lives; however, patients frequently face prolonged waiting periods as a result of the insufficient availability of suitable donors.

23 Nov 2023

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

17 Nov 2023

A Surprising Control Mechanism of Chlamydomonas Cell Division

Headed by James Umen, PhD, a team of international researchers at the Donald Danforth Plant Science Center has uncovered a surprising revelation about the single-celled green alga Chlamydomonas and its control over cell division.

16 Nov 2023

Circular Extrachromosomal DNA Linked to Medulloblastoma Relapse and Death

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA-;loops of DNA found outside of regular chromosomes-;are twice as likely to relapse and three times as likely to die within five years of diagnosis.

15 Nov 2023

Cancer Stem Cells Induce Macrophage Senescence, Creating Conditions for Tumor Formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

15 Nov 2023

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

10 Nov 2023

SPT5 Identified as a Potential Target Protein for Treatment of MYC-Dependent Cancers

MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins - with clear consequences for the tumor.

8 Nov 2023

Study Identifies Risk Genes and Regulatory Variants for Colorectal Cancer by Integrating Multi-Omics Data

This study was led by Prof. Xiao-Ping Miao' team from the School of Public Health, Wuhan University, in collaboration with Prof. Shaokai Zhang from the Henan Cancer Hospital.

2 Nov 2023

Exploring the Role of Extracellular Vesicles in Cellular Communication

A research project, jointly conducted by scientists affiliated with the Germans Trias i Pujol Research Institute, has uncovered the potential advantages of employing an agarose spot migration assay for assessing the capacity of extracellular vesicles to attract neighboring cells within a controlled setting.

1 Nov 2023

DNA’s Role in Glioblastoma: Insights from Umeå University’s Research

A groundbreaking research conducted at Umeå University in Sweden has revealed that the three-dimensional arrangement of DNA can impact the development of aggressive brain cancer, glioblastoma.

1 Nov 2023

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

Enhancing treatment options for triple-negative breast cancer (TNBC), a highly aggressive tumor with a grim prognosis and limited therapeutic possibilities has proven to be a formidable challenge.

31 Oct 2023

New Modular Nanoparticle Technology Opens the Door to a Variety of Therapeutic Approaches

Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins.

31 Oct 2023

ISB Researchers Discover Genetic Key to T Cell Development

T cells are soldiers on the front lines of the human immune system. They are responsible for many important roles, including attacking viral- or bacterial-infected cells and certain cancer cells, and immunological memory – remembering the specific pathogens or the cancer signatures that originally trigger T cells.

26 Oct 2023

New Insight Into How Cancer Cells Function in Softer Tissue Environments

A collaborative research team from the University of Turku and Turku Bioscience Centre, in conjunction with Misvik Biology Ltd in Finland, has introduced a novel technique for investigating the behavior of cancer cells in both softer and stiffer tissue environments.

19 Oct 2023

New Way to Visualize Tumors During Surgery

Surgeons often face the challenge of achieving precise tumor removal while preserving healthy tissue. Traditionally, they rely on their visual and tactile senses to determine where to make incisions.

17 Oct 2023

New Atlases Reveal Unprecedented Detail of the Human Brain

In two concurrent projects, scientists at the Karolinska Institutet have played a significant role in producing the most extensive atlases of human brain cells to date.

13 Oct 2023

Researchers Develop Drug Targeting lncRNA TUG1 to Control Brain Tumor Growth in Mice

A new study has unraveled a crucial link between how cancer cells cope with replication stress and the role of Taurine Upregulated Gene 1 (TUG1). By targeting TUG1 with a drug, the researchers were able to control brain tumor growth in mice, suggesting a potential strategy to combat aggressive brain tumors such as glioblastomas.